From: Ken on
I have been recently been diagnosed and I have a couple of questions.

The girl that I believe gave me HSV2 has been tested at least twice and
the tests were negative both times. There is extremely good reason to
think it was her. Second partner at 21 years of marriage, Ex claims no
sex outside marriage and I believe her one of the reasons I left. I have
no doubt but I don't understand. Is she lying about getting clear tests?

Second I feel like a loaded gun. I have a new partner and I am really
concerned about how I should act and protect her. For example sleeping
in the same bed naked.

Thanks
From: M2slo2cht on
I wouldn't know if she's lying or not and it seems at this point it's
a moot question.
As far as sleeping naked with your partner, as long as you're actually
asleep, no problem. In other words, the virus won't transfer from you
to the sheets and then her. It's skin to skin contact that does it. If
you're having an outbreak you could wear underwear as a precaution.
But otherwise the risk of transfer would be pretty low. And as time
goes by, the risk will be even lower.

M2

Ken writes:
>I have been recently been diagnosed and I have a couple of questions.
>
>The girl that I believe gave me HSV2 has been tested at least twice and
>the tests were negative both times. There is extremely good reason to
>think it was her. Second partner at 21 years of marriage, Ex claims no
>sex outside marriage and I believe her one of the reasons I left. I have
>no doubt but I don't understand. Is she lying about getting clear tests?
>
>Second I feel like a loaded gun. I have a new partner and I am really
>concerned about how I should act and protect her. For example sleeping
>in the same bed naked.
>
>Thanks
From: Ken on
On Sun, 29 Jun 2008 18:30:33 -0500, M2slo2cht wrote:

> I wouldn't know if she's lying or not and it seems at this point it's a
> moot question.

I am trying to understand the testing process, reliability etc. I am
also concerned if she goes into denial and then infects someone else. I
think that it is certain she is actually positive since we had sex during
the initial outbreak because I did not know what it was.

I am not sure how I will tackle it with her or even if I will I am just
trying to understand.

> As far as sleeping naked with your partner, as long as you're actually
> asleep, no problem. In other words, the virus won't transfer from you to
> the sheets and then her. It's skin to skin contact that does it. If
> you're having an outbreak you could wear underwear as a precaution. But
> otherwise the risk of transfer would be pretty low. And as time goes by,
> the risk will be even lower.

This is what I don't really understand. In my reading I remember
something about an outbreak occurring before symptoms, ie virus being
present on the skin. So can I be active and not know it yet.

Second thing is where does the virus appear, only on the site of the
first outbreak. I don't really understand why other body parts are not
active.

Ta
From: M2slo2cht on
Ken writes:
>I am trying to understand the testing process, reliability etc.

Depends on which test you're lookin' at.. First, the Swab (culture)
type test has a 50% false negative rate which isn't very good but it
has a good accuracy rate for a positive result. A swab must be done on
an outbreak that is present and visible.
Second, the newest blood tests are very accurate as long as the sample
is taken at least 12-16 weeks after infection. A test done earlier
than that has a much higher false negative rate. But an outbreak isn't
necessary for a blood test to be done. A blood test looks for
antibodies in the blood so it can give you a fairly definite yes or no
to infection, and tell you which type virus it is (Type 1 vs Type 2)
but it can't tell you where the infection is located (genital vs oral)
like a swab type test can do. Even if suspected symptoms are present,
a positive blood test result can't tell you for sure that the symptoms
you're seeing aren't caused by something else.

>This is what I don't really understand. In my reading I remember
>something about an outbreak occurring before symptoms, ie virus being
>present on the skin. So can I be active and not know it yet.

Yes, virus can be shed from the skin even when there is no visible
outbreak. I'll explain further below.

>Second thing is where does the virus appear, only on the site of the
>first outbreak. I don't really understand why other body parts are not
>active.

After infection, the virus sets up housekeeping in the Sacral Ganglia
where it lies dormant most of the time doing no harm. The Sacral
Ganglia is at the base of the spine and is the root of the sensory
nerves serving the skin in the boxer shorts area. Occasionally, the
dormant virus reactivates and starts replicating (pumping out new
viruses) at which point the new viruses travels up a nerve (staying
within the nerve) to the surface of the skin. The location where it
surfaces is dependant upon which nerve it travels. Sometimes it goes
up the same nerve it came in on when infection took place. But it can
also travel up a different nerve to surface in a different location.
The mechanism that causes the dormant virus to reactivate isn't fully
understood but a number of possible triggers are identified. Certain
foods, stress, friction, that sort of thing. Everybody has different
triggers. The choice of which nerve to take to the skin's service
seems to be the path of least resistance but that path is impossible
to predict.
As I mentioned, viral shedding can occur without symptoms but at some
point the volume of virus becomes so great that an outbreak is the
result. So that's why you get virus accumulating on the skin surface
before the symptoms appear.

I hope that helps clear things up a little.

M2