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From: Tom Anderson on 15 Sep 2008 14:29
On Sun, 14 Sep 2008, WannabeSomeoneCares(a)gmail.com wrote:

> "RichD" <r_delaney2001(a)yahoo.com> wrote in message news:
> 6b0962cc-3d96-4b48-aa62-6e587a4dcfaa(a)a1g2000hsb.googlegroups.com...
>
>> Anybody know anything about creatine?
>
> I have used creatine on and off for quite many years. It provides you
> with the energy for endurance in anaerobic respiration. It is legal and
> harmless. The side-effort is water retention inside the muscle cells
> (inside each individual cell instead of outside between cells).

Indeed, some scientists believe that this is not just a side-effect, it's
the main mechanism by which creatine drives hypertrophy - increased water
retention swells the cells, which stimulates them to synthesise more
protein.

Okay, so it's only me that believes this, but i have a kind of plausible
mechanism for it, with tons of experimental evidence for the various
steps. Mostly in hepatocytes, but liver, muscle, same difference, you
know.

Anyway, er, yes, creatine causes a modest but reproducable increase in
muscle mass and muscular endurance. There are no definitively established
serious side effects - people report all sorts of things, but nothing's
stood up to controlled trials.

tom

--
Operate all mechanisms!
From: SPORTfighter on 15 Sep 2008 14:58
On Sep 14, 8:41 pm, RichD <r_delaney2...(a)yahoo.com> wrote:
> Anybody know anything about creatine?
>
> I saw a can, it says one scoop before
> a workout, one scoop after, builds lean
> muscles, etc.
>
> I will never take steroids, but is this stuff
> worth anything?
>
> --
> Rich

yeah, gives me atomic diarrhea, i mean moreso.
From: YumYumPandaburger on 18 Sep 2008 07:20
On 15 sep, 03:24, WannabeSomeoneCa...(a)gmail.com wrote:
> "RichD" <r_delaney2...(a)yahoo.com> wrote in message news:
>
> 6b0962cc-3d96-4b48-aa62-6e587a4dc...(a)a1g2000hsb.googlegroups.com...
>
> > Anybody know anything about creatine?
>
> > I saw a can, it says one scoop before
> > a workout, one scoop after, builds lean
> > muscles, etc.
>
> > I will never take steroids, but is this stuff
> > worth anything?
>
> > --
> > Rich
>
> I have used creatine on and off for quite many years. It provides you
> with the energy for endurance in anaerobic respiration. It is legal
> and harmless. The side-effort is water retention inside the muscle
> cells (inside each individual cell instead of outside between cells).
> This may be a desirable side-effect because it bulks up you muscle and
> you look good in muscle-man competitions.
>
> This website which sells body building products has very good articles
> on creatine:http://www.bodybuilding.com/fun/bbinfo.php?page=Creatine
>
> This is what Wikipedia says about creatine:http://en.wikipedia.org/wiki/Creatine#Function
> Creatine, by way of conversion to and from phosphocreatine, functions
> in all vertebrates and some invertebrates, in conjunction with the
> enzyme creatine kinase. A similar system based on arginine/
> phosphoarginine operates in many invertebrates via the action of
> Arginine Kinase. The presence of this energy buffer system keeps the
> ATP/ADP ratio high at subcellular places where ATP is needed, which
> ensures that the free energy of ATP remains high and minimizes the
> loss of adenosine nucleotides, which would cause cellular dysfunction.
> Such high-energy phosphate buffers in the form of phosphocreatine or
> phosphoarginine are known as phosphagens. In addition, due to the
> presence of subcompartmentalized Creatine Kinase Isoforms at specific
> sites of the cell, the phosphocreatine/creatine kinase system also
> acts as an intracellular energy transport system from those places
> where ATP is generated (mitochondria and glycolysis) to those places
> where energy is needed and used, e.g., at the myofibrils for muscle
> contraction, at the sarcoplasmic reticulum (SR) for calcium pumping,
> and at the sites of many more biological processes that depend on
> ATP..........................................
>
> ......................
>
> Wannabe
>
> =======

You speaketh the truth.
From: YumYumPandaburger on 18 Sep 2008 07:21
On 15 sep, 02:41, RichD <r_delaney2...(a)yahoo.com> wrote:
> Anybody know anything about creatine?
>
> I saw a can, it says one scoop before
> a workout, one scoop after, builds lean
> muscles, etc.
>
> I will never take steroids, but is this stuff
> worth anything?
>
> --
> Rich

It is one of the only supplements that has been proven to have any
impact at all.

It makes me cramp much faster, even if I drink a lot of water to
counter that. Taking magnesium makes the cramping syndrme go away
though
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