From: Just on
On Sun, 27 Jul 2008 15:55:02 -0400, "Steve Kramer"

>> I thought I should mention my PSA level though, to indirectly
>> emphasize the importance (I believe) of going into SRT with a pretty
>> low PSA.
>
>I concur. I firmly believe aggressive therapy is the key to sustaining
>life.


Well... I agree if / when it is +/- clear that aggressive therapy is
more effective than less aggressive alternatives...

In the case of SRT there seems to be a case for aggressive therapy.

Just
From: I.P. Freely on
Steve Kramer wrote:
> <rosbif> wrote in message news:m8mk849vm9tjrtaeo5v1caak595ga8p904(a)4ax.com...
>> On Fri, 25 Jul 2008 13:49:52 -0700, "I.P. Freely"
>> <fuhgheddaboutit(a)noway.nohow> wrote:
>>
>>> I still hope that if/when my PC does return, the
>>> supersensitive tests will give me some extra time for research and
>>> introspection before action is clearly required.
>>
>> But at what value would action be clearly required?
>>
>
> Again, assuming post-surgery and pre-radiation, my doctor was aggressive
> when he signed me up for radiation when I hit 0.37. I don't think anyone on
> the NG had RT with less than 0.37.... Maybe those without negative margins.
> Most people, especially those who had this before me, started radiation
> about 1.0. Of course, doctors vary.

My onc told me to start worrying @ 0.10 and the classic action point is
@ 0.20, at least with my G-8 and SVI. But he also says SRT would help my
odds, which I gather is mighty optimistic in my case, so I'm guessing
he's playing it very conservative.

I.P.
From: I.P. Freely on
Larry Sabo wrote:
> I did not have negative margins, unfortunately.

Your positive margins raise the odds that your recurrence is local and
thus subject to SRT. Could be a good thing.

I.P.
From: I.P. Freely on
Just wrote:
>
> In the case of SRT there seems to be a case for aggressive therapy.

In my case -- G8, SVI, neg margins -- SRT is of dubious value, thus may
warrant yet another tough decision regarding whether and when.

I.P.
From: rosbif on
On Sat, 26 Jul 2008 15:14:28 +0100, Just <here(a)anon.com> wrote:

>On Fri, 25 Jul 2008 20:20:49 -0400, "Steve Kramer"
><skramer(a)cinci.rr.com> wrote:
>
>>Again, assuming post-surgery and pre-radiation, my doctor was aggressive
>>when he signed me up for radiation when I hit 0.37. I don't think anyone on
>>the NG had RT with less than 0.37.... Maybe those without negative margins.
>>Most people, especially those who had this before me, started radiation
>>about 1.0. Of course, doctors vary.
>
>
>"I don't think anyone on the NG had RT with less than 0.37": not
>really... please see my data below.
>
>
>Pre RRP PSA: 18.5
>
>RRP: March 1999
>Extra-capsular extension: negative
>Lymph node involvement: negative
>Seminal vesicle involvement: negative
>Perineural invasion: negative
>Surgical margins: negative
>
>
>PSA:
>Until March 2001: <0.04
>March 2001: 0.04
>October 2001: 0.07
>January 2002: 0.10
>January 2002: 0.06 (one week later)
>April 2002: 0.05 (different Lab; different assay).
>October 2002: 0.08
>April 2003: 0.10
>November 2003: 0.12.
>February 2004: 0.13.
>June 2004: 0.14
>November 2004: 0.18
>March 2005: 0.21
>
>SRT: March - May 2005
>65 gy (45 gy to the pelvic area + 20 gy to the prostatic fossa)
>
>PSA until now: <0.02
>
>
>best wishes.
>
>Just


Thanks for posting this - it looks like SRT did the trick - excellent!
May your low PSAs continue indefinitely.
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