You can not win.
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From: guys on 12 Aug 2008 10:36 For a long time I had my diabetes under good control. Recent med's and system changes has started a new game. If I take enough Lantus to maintain basal, that amount will lower my blood glucose down excessively while I sleep. Before you offer an answer, remember I have zilch release of glucose on low blood sugars. I post this as an informational post. No use complaining about docs, it will upset some biased soul. ----== Posted via Pronews.Com - Unlimited-Unrestricted-Secure Usenet News==---- http://www.pronews.com The #1 Newsgroup Service in the World! >100,000 Newsgroups ---= - Total Privacy via Encryption =---
From: M�ck�� on 12 Aug 2008 13:25 On Tue, 12 Aug 2008 09:36:17 -0500, guys(a)consolidated.net wrote: > >For a long time I had my diabetes under good control. > >Recent med's and system changes has started a new game. > >If I take enough Lantus to maintain basal, that amount >will lower my blood glucose down excessively while I sleep. > >Before you offer an answer, remember I have zilch release >of glucose on low blood sugars. I post this as an >informational post. The only way someone has zero glucose release on low blood sugars as you put it, is if they are having many hypos, depleting the liver's glycogen stores and or having too much insulin onboard (in the system) overcoming any glycogen release that does take place. Normally caused by taking too much insulin. Go to your doctor and discuss getting (borrowing) a CGMS (Continous Glucose Monitoring System) and using it to track your BG profile for a week, then do a second profile a short time later. You live in Houston Texas, please don't claim that there are no diabetic specialists who use loaner CGMS units to profile their patients BGs. -- M�ck�� Deltec CoZmore Pumper Type 1 since 1975 http://www.alt-support-diabetes.org http://www.diabetic-talk.org http://www.insulin-pumpers.org http://diabetes.niddk.nih.gov/dm/pubs/type1and2/ http://www.pandora.com enter "Jason & Demarco" http://www.ratbags.com/dechunging/ "To announce that there must be no criticism of the President, or that we are to stand by the President right or wrong, is not only unpatriotic and servile, but is morally treasonable to the American public." ....Theodore Roosevelt (o �) --ooO-(_)-Ooo-------------------- "I don't know half of you half as well as I should like; and I like less than half of you half as well as you deserve." ....Bilbo Baggins DISCLAIMER If you find a posting or message from me offensive, inappropriate, or disruptive, please ignore it. If you don't know how to ignore a posting, complain to me and I will be only too happy to demonstrate... ..
From: Charly Coughran on 12 Aug 2008 13:54 guys(a)consolidated.net wrote in news:ps63a41c83ludr9ftsqu5itqrv74aogiit(a)4ax.com: > > For a long time I had my diabetes under good control. > > Recent med's and system changes has started a new game. > > If I take enough Lantus to maintain basal, that amount > will lower my blood glucose down excessively while I sleep. > > Before you offer an answer, remember I have zilch release > of glucose on low blood sugars. I post this as an > informational post. > > No use complaining about docs, it will upset some biased > soul. > > > ----== Posted via Pronews.Com - Unlimited-Unrestricted-Secure Usenet > News==---- http://www.pronews.com The #1 Newsgroup Service in the > World! >100,000 Newsgroups ---= - Total Privacy via Encryption =--- Without more detail about your current regimen, the regimen that used to work, and what you think the system changes are that seem to be causing problems, only general comments can be made. I assume that by "maintain basal" you mean that you can skip any meal and your glucose level will remain level enough to not require insulin or food for correction until the next regularly scheduled meal time. Although the quoted numbers vary greatly, it is clear that many need to split their Lantus dose in two for best results. A small percentage need to split their dose into three. Dose timing can also be critical to move insulin peaks to match peaks in glucose load. Lantus is not as flat for everyone as the averaged curves would lead you to believe. In general, the longer the curve of action of an insulin, the greater the inter patient variability. It is important to get a good profile of your overnight glucose level. If you can't get access to a continuous profiler, give up a nights good sleep and set an alarm to test every hour from bedtime to breakfast. I was in an experimental trial in which we wore a continuous glucose tester for 3 days. When the experiment was over, the nurse in charge broke protocol and showed 2 of us our three day plots. We both had a dramatic, sharp decline in blood glucose around 5am even though we were both pumpers with constant infusion overnight. Sort of a negative dawn phenomena. 2 out of 17 or 12%. The standard doctor's response to that is, "that doesn't happen in type 1 diabetics". -- ------- Charly Coughran ccoughran(a)DELETE-TO-RESPOND-UCSD.EDU
From: guys on 12 Aug 2008 15:42 On Tue, 12 Aug 2008 17:54:24 +0000 (UTC), Charly Coughran <ccoughran(a)REMOVE-TO-DELETE-UCSD.EDU> wrote: >guys(a)consolidated.net wrote in >news:ps63a41c83ludr9ftsqu5itqrv74aogiit(a)4ax.com: > >> >> For a long time I had my diabetes under good control. >> >> Recent med's and system changes has started a new game. >> >> If I take enough Lantus to maintain basal, that amount >> will lower my blood glucose down excessively while I sleep. >> >> Before you offer an answer, remember I have zilch release >> of glucose on low blood sugars. I post this as an >> informational post. >> >> No use complaining about docs, it will upset some biased >> soul. >> >> >> ----== Posted via Pronews.Com - Unlimited-Unrestricted-Secure Usenet >> News==---- http://www.pronews.com The #1 Newsgroup Service in the >> World! >100,000 Newsgroups ---= - Total Privacy via Encryption =--- > >Without more detail about your current regimen, the regimen that used >to work, and what you think the system changes are that seem to be >causing problems, only general comments can be made. I assume that by >"maintain basal" you mean that you can skip any meal and your glucose >level will remain level enough to not require insulin or food for >correction until the next regularly scheduled meal time. > >Although the quoted numbers vary greatly, it is clear that many need >to split their Lantus dose in two for best results. A small >percentage need to split their dose into three. Dose timing can also >be critical to move insulin peaks to match peaks in glucose load. >Lantus is not as flat for everyone as the averaged curves would lead >you to believe. In general, the longer the curve of action of an >insulin, the greater the inter patient variability. > >It is important to get a good profile of your overnight glucose level. >If you can't get access to a continuous profiler, give up a nights >good sleep and set an alarm to test every hour from bedtime to >breakfast. I was in an experimental trial in which we wore a >continuous glucose tester for 3 days. When the experiment was over, >the nurse in charge broke protocol and showed 2 of us our three day >plots. We both had a dramatic, sharp decline in blood glucose around >5am even though we were both pumpers with constant infusion overnight. >Sort of a negative dawn phenomena. 2 out of 17 or 12%. The standard >doctor's response to that is, "that doesn't happen in type 1 >diabetics". Thanks Charly. For several years I had good control with a single dose of Lantus per day. I do use use Humalog for bolus and i know what I eat and can cover it well and verify that with tests. I had a a problem with skin eruptions for quite a while. I had no idea I had a parasite infection. I we totally unaware of them. It went very gross and I had to force the issue. I realize someting was wrong and started some research. From the symptoms I found my problem fitted parasites When the proper drugs were used it abated but it is evident I may have to deal with the rest of my life. From what happened during treatment and what improved it had done a lot of damage. Still the docs want to under treat it because the drugs are toxic. . It was so gross, I do not care. But it has had bad effet on internal organs and my diabetic control has been difficult. The intestinal tract is damaged and evidently my required use of Flomax is related to the infection. I have dropped my use of Epogen whch was damn expensive. I am losing a lot less blood. The loss is suttle and easily attributed to diabetic issues.. I was in the hospital in January and was isolated due to arm lesions. At the worst I was not sleeping for two or three nights or until complete exhaustion set in. I am on a drug called Vermox and have used potsassium Iodide and Albenza. The data on this infection is scattered and contradictory. I am slowly working on my control and slowly gaining on it. Charly, you have helped so much in the past and post the along with the best.and I thank you for that. If a few here had to go through ten docs and had to yell at one that had collected money for years. "WE need to not go there, I have a systemic parasite infection and something has to be done about it Unfortunately that is true. I set at this terminal with no severe "stings" and set hoping It is under control. But I still take some drugs that some tell me could fail my kidneys and\or liver. Both are probably damaged by the Helminth type of parasites. They are a growing probem in the US. I prefer to be a bit vague on this public forum but I think it time for me be more candid. I do not want to provoke false probems in others but to raise ideas and let the collective knowledge work. I apologize to the posters that have helped me so much. I tried and evidently it did not work. My fault. Thank you again. Guy ----== Posted via Pronews.Com - Unlimited-Unrestricted-Secure Usenet News==---- http://www.pronews.com The #1 Newsgroup Service in the World! >100,000 Newsgroups ---= - Total Privacy via Encryption =---
From: Charly Coughran on 13 Aug 2008 15:32 guys(a)consolidated.net wrote in news:iem3a499acudlrc7d23m5a5i2n59rk49ov(a)4ax.com: > On Tue, 12 Aug 2008 17:54:24 +0000 (UTC), Charly Coughran > <ccoughran(a)REMOVE-TO-DELETE-UCSD.EDU> wrote: > >>guys(a)consolidated.net wrote in >>news:ps63a41c83ludr9ftsqu5itqrv74aogiit(a)4ax.com: >> >>> >>> For a long time I had my diabetes under good control. >>> >>> Recent med's and system changes has started a new game. >>> >>> If I take enough Lantus to maintain basal, that amount >>> will lower my blood glucose down excessively while I sleep. >>> >>> Before you offer an answer, remember I have zilch release >>> of glucose on low blood sugars. I post this as an >>> informational post. >>> >>> No use complaining about docs, it will upset some biased >>> soul. >>> >>> >>> ----== Posted via Pronews.Com - Unlimited-Unrestricted-Secure >>> Usenet News==---- http://www.pronews.com The #1 Newsgroup Service >>> in the World! >100,000 Newsgroups ---= - Total Privacy via >>> Encryption =--- >> >>Without more detail about your current regimen, the regimen that >>used to work, and what you think the system changes are that seem to >>be causing problems, only general comments can be made. I assume >>that by "maintain basal" you mean that you can skip any meal and >>your glucose level will remain level enough to not require insulin >>or food for correction until the next regularly scheduled meal time. >> >>Although the quoted numbers vary greatly, it is clear that many need >>to split their Lantus dose in two for best results. A small >>percentage need to split their dose into three. Dose timing can >>also be critical to move insulin peaks to match peaks in glucose >>load. Lantus is not as flat for everyone as the averaged curves >>would lead you to believe. In general, the longer the curve of >>action of an insulin, the greater the inter patient variability. >> >>It is important to get a good profile of your overnight glucose >>level. If you can't get access to a continuous profiler, give up a >>nights good sleep and set an alarm to test every hour from bedtime >>to breakfast. I was in an experimental trial in which we wore a >>continuous glucose tester for 3 days. When the experiment was over, >>the nurse in charge broke protocol and showed 2 of us our three day >>plots. We both had a dramatic, sharp decline in blood glucose >>around 5am even though we were both pumpers with constant infusion >>overnight. Sort of a negative dawn phenomena. 2 out of 17 or 12%. >>The standard doctor's response to that is, "that doesn't happen in >>type 1 diabetics". > > Thanks Charly. For several years I had good control with a single > dose of Lantus per day. I do use use Humalog for bolus and i know > what I eat and can cover it well and verify that with tests. > > I had a a problem with skin eruptions for quite a while. I > had no idea I had a parasite infection. I we totally unaware of > them. It went very gross and I had to force the issue. I realize > someting was wrong and started some research. From the symptoms I > found my problem fitted parasites When the proper drugs were used > it abated but it is evident I may have to deal with the rest of my > life. > > From what happened during treatment and what improved it > had done a lot of damage. Still the docs want to under treat it > because the drugs are toxic. . It was so gross, I do not care. > > But it has had bad effet on internal organs and my diabetic > control has been difficult. The intestinal tract is damaged > and evidently my required use of Flomax is related to the > infection. I have dropped my use of Epogen whch was > damn expensive. I am losing a lot less blood. The loss is > suttle and easily attributed to diabetic issues.. > > I was in the hospital in January and was isolated due > to arm lesions. At the worst I was not sleeping for two > or three nights or until complete exhaustion set in. > > I am on a drug called Vermox and have used potsassium Iodide > and Albenza. The data on this infection is scattered and > contradictory. > > I am slowly working on my control and slowly gaining on it. > > Charly, you have helped so much in the past and post the along > with the best.and I thank you for that. > > If a few here had to go through ten docs and had to yell at one > that had collected money for years. "WE need to not go there, I > have a systemic parasite infection and something has to be > done about it Unfortunately that is true. > > I set at this terminal with no severe "stings" and set hoping It > is > under control. But I still take some drugs that some tell me could > fail my kidneys and\or liver. Both are probably damaged by the > Helminth type of parasites. They are a growing probem in the US. > > I prefer to be a bit vague on this public forum but I think it time > for me be more candid. I do not want to provoke false > probems in others but to raise ideas and let the collective > knowledge work. > > I apologize to the posters that have helped me so much. > I tried and evidently it did not work. My fault. > > Thank you again. > > Guy > > > ----== Posted via Pronews.Com - Unlimited-Unrestricted-Secure Usenet > News==---- http://www.pronews.com The #1 Newsgroup Service in the > World! >100,000 Newsgroups ---= - Total Privacy via Encryption =--- > Additional underlying medical problems can make everything much more difficult both from the disease and the treatment. A friend of mine just went through a bout of shingles and gout. The treatment of each aggravates the other so they were constantly adjusting the treatment to try to get both to improve rather than one improving and the other getting worse. Knowing absolutely nothing about Helminth parasites, I did some poking around. An interesting, and depressing, review can be found at http://iai.asm.org/cgi/content/full/70/2/427 I hope you can continue improving your control. You have no cause to apologize to anyone. -- ------- Charly Coughran ccoughran(a)DELETE-TO-RESPOND-UCSD.EDU
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