Why are so many women getting MS? - 30 April 2007
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From: JOHN on 30 Apr 2007 10:38 http://www.whale.to/vaccine/miller345.html
From: James Michael Howard on 3 May 2007 10:19 An Explanation of the Current Increase in Multiple Sclerosis in Women Copyright 2007, James Michael Howard, Fayetteville, Arkansas, U.S.A. I wish to suggest an explanation for the increase in multiple sclerosis currently demonstrated in the population. When treated with testosterone, male and female rats, 5alpha-reductase type 2 mRNA while decreasing type 1 mRNA (Neurochem Int 2006; 49: 626-30). Earlier work has suggested that 5alpha-reductase type 1 isoform is the "most relevant 5alpha-R present in myelin" (Mol Cell Endocrinol 1997; 129: 181-90). It is my hypothesis that the "secular trend," the increase in size and earlier puberty of children, is caused by an increase in the percentage of women of higher testosterone with time within the population. This means that women of higher testosterone may be increasing and myelination may be adversely affected by an increase in the ratio of 5alpha-reductase type 2 to type 1. I suggest the current rise in multiple sclerosis may be occurring as the numbers of women of higher testosterone increase. Multiple sclerosis is lower in males and blacks, compared to whites. I suggest increased testosterone in males, and the findings that blacks produce more testosterone than whites, may result in reduced births of these individuals due to negative pregnancy outcomes. That is, individuals of higher testosterone are negatively affected prior to birth and do not survive to be counted as cases of multiple sclerosis. This may also explain why more females are born compared to males and why blacks exhibit more problems with negative pregnancy outcomes. This may explain why women are increasing in multiple sclerosis at this time.
From: bigvince on 19 May 2007 15:28 On May 3, 10:19 am, James Michael Howard <jmhow...(a)anthropogeny.com> wrote: > An Explanation of the Current Increase in Multiple Sclerosis in Women > > Copyright 2007, James Michael Howard, Fayetteville, Arkansas, U.S.A. > > I wish to suggest an explanation for the increase in multiple sclerosis > currently demonstrated in the population. When treated with testosterone, > male and female rats, 5alpha-reductase type 2 mRNA while decreasing type 1 > mRNA (Neurochem Int 2006; 49: 626-30). Earlier work has suggested that > 5alpha-reductase type 1 isoform is the "most relevant 5alpha-R present in > myelin" (Mol Cell Endocrinol 1997; 129: 181-90). > > It is my hypothesis that the "secular trend," the increase in size and > earlier puberty of children, is caused by an increase in the percentage of > women of higher testosterone with time within the population. This means > that women of higher testosterone may be increasing and myelination may be > adversely affected by an increase in the ratio of 5alpha-reductase type 2 > to type 1. > > I suggest the current rise in multiple sclerosis may be occurring as the > numbers of women of higher testosterone increase. Multiple sclerosis is > lower in males and blacks, compared to whites. I suggest increased > testosterone in males, and the findings that blacks produce more > testosterone than whites, may result in reduced births of these individuals > due to negative pregnancy outcomes. That is, individuals of higher > testosterone are negatively affected prior to birth and do not survive to > be counted as cases of multiple sclerosis. This may also explain why more > females are born compared to males and why blacks exhibit more problems > with negative pregnancy outcomes. This may explain why women are > increasing in multiple sclerosis at this time. There is a pretty good like between vitamin d levels and MS. perhaos our inordinate fear of sunlight that has been cultivated for the past 20 years is a part of this equation. Thanks Vince
From: John H. on 22 May 2007 12:43
Sunlight and vitamin D production are associated with reduced risk of MS, reduced amyloidsis, very slight effect oin schizophrenia incidence, and reduced systemic inflammation. You're right, it's sunophobia. Try< The UV Advantage, Professor Holick. "bigvince" <Vince.Miraglia(a)gmail.com> wrote in message news:1179602892.369361.183950(a)h2g2000hsg.googlegroups.com... > On May 3, 10:19 am, James Michael Howard <jmhow...(a)anthropogeny.com> > wrote: > > An Explanation of the Current Increase in Multiple Sclerosis in Women > > > > Copyright 2007, James Michael Howard, Fayetteville, Arkansas, U.S.A. > > > > I wish to suggest an explanation for the increase in multiple sclerosis > > currently demonstrated in the population. When treated with testosterone, > > male and female rats, 5alpha-reductase type 2 mRNA while decreasing type 1 > > mRNA (Neurochem Int 2006; 49: 626-30). Earlier work has suggested that > > 5alpha-reductase type 1 isoform is the "most relevant 5alpha-R present in > > myelin" (Mol Cell Endocrinol 1997; 129: 181-90). > > > > It is my hypothesis that the "secular trend," the increase in size and > > earlier puberty of children, is caused by an increase in the percentage of > > women of higher testosterone with time within the population. This means > > that women of higher testosterone may be increasing and myelination may be > > adversely affected by an increase in the ratio of 5alpha-reductase type 2 > > to type 1. > > > > I suggest the current rise in multiple sclerosis may be occurring as the > > numbers of women of higher testosterone increase. Multiple sclerosis is > > lower in males and blacks, compared to whites. I suggest increased > > testosterone in males, and the findings that blacks produce more > > testosterone than whites, may result in reduced births of these individuals > > due to negative pregnancy outcomes. That is, individuals of higher > > testosterone are negatively affected prior to birth and do not survive to > > be counted as cases of multiple sclerosis. This may also explain why more > > females are born compared to males and why blacks exhibit more problems > > with negative pregnancy outcomes. This may explain why women are > > increasing in multiple sclerosis at this time. > > There is a pretty good like between vitamin d levels and MS. perhaos > our inordinate fear of sunlight that has been cultivated for the past > 20 years is a part of this equation. Thanks Vince > |