From: Dick Smith on
What I really do not understand is why the odds seems to increase
substantially that PCa returns after 10 or 15 years.

If a man was monitoring his PSA and PCa was found in the early stages
and subsequently had a RRP performed what are his odds of having PCa
return after 15 years? and Why?

What I don't understand is from some general reading I've done. They
say that (roughly) 1 in 10 men who get PCa will die from it. Yet that
seems counter to the notion that roughly 1/3 of men with PCa after 15
years will die from it.

Are there cancer cells that were missed? If so, why not do EBR after
surgery?

From: I.P. Freely on
Alan Meyer wrote:
> A rad onc told me that surgeons _think_ they got all the prostate
> tissue out, but they can't know for sure. A surgeon once told me
> that rad oncs _think_ their radiation kills all the cancer, but they
> can't know that for sure either.

Neither promised me anything; the best reassurance I got was one simple
"fact": negative margins. Whoopie; even if true and even at a cellular
level, there are still cancer cells in my blood stream and no doubt
others lodged in distant spots, all looking hard for a spot with
favorable conditions to flourish. The higher our Gleason score, the
greater their odds of success. Given that and my G8, all my negative
margins do for me is shift my cancer's return odds towards distant ---
i.e., incurable -- mets.

With any luck I'll die of a heart attack instead. That would be a HUGE
victory, given that my heart is apparently very healthy.

I.P.
From: I.P. Freely on
Clarence Crow wrote:
> this is apparently minimised by keeping your Immune System healthy.

Which ALSO requires walking a tightrope . . . between sufficient
exercise and too much exercise.

I.P.
From: I.P. Freely on
John Loomis wrote:
> I am not sure where you come up with re- accurance...After 10 to 15 years,
> and please give me your details..
> If you have a Dr. and do a biopsy, and decide your route,
> You will either be having RP, and or having Rp, and Radiation.
> You may have hormone, and such. Ablaition...
> I am confused with your statement and 15 year return...if not 10.
> Where are you getting this info from?

It's commonly known, and studies support, that PC often takes a turn for
the worse around the 15-year point.

I.P.
From: dave perry on
Is this with treatment or without treatment? When I was diagnosed I
read that if left untreated, a typical G6 patient had a 20% chance of
being dead from PCa at 15 years with a sharp increase after that. With
treatment, there is a steady decline in recurrence rates. I also read
that any recurrence after 10 years is likely to be a new cancer in some
left over prostate tissue, not a recurrence. I'm pretty sure that is
some doctor's guess, not data from a study.
Dave Perry
I.P. Freely wrote:
> John Loomis wrote:
> > I am not sure where you come up with re- accurance...After 10 to 15 years,
> > and please give me your details..
> > If you have a Dr. and do a biopsy, and decide your route,
> > You will either be having RP, and or having Rp, and Radiation.
> > You may have hormone, and such. Ablaition...
> > I am confused with your statement and 15 year return...if not 10.
> > Where are you getting this info from?
>
> It's commonly known, and studies support, that PC often takes a turn for
> the worse around the 15-year point.
>
> I.P.

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