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From: Jeff on 27 Dec 2005 22:28 Greetings. Very concerned as I am already very,very overweight ("obese" to be precise) and all of the meds seem to slow down metabolism...have been on Cymbalta and cannot ascertain its weight gaininig potential yet but suspect it maybe, excuse me here, very constipating and therefore contributing to weight gain. Any weight loss and/or gain experiences with Cymbalta?
From: Cassandra on 28 Dec 2005 00:08 At first, I lost weight on Cymbalta, but I think I ended up gaining weight later on in treatment with it. It didn't constipate me, though. Sorry I can't help you with accuracy, I've gained over 50 pounds in the past year with various causes, so don't know how much Cymbalta affected that. For what it's worth, though, pretty much all the SRIs will have some initial weight LOSS, but weight gain after about four months. Good luck.
From: Jean Barto on 28 Dec 2005 00:09 On 12/27/05 10:28 PM, in article 1135740531.866873.10740(a)g14g2000cwa.googlegroups.com, "Jeff" <reedgw(a)adelphia.net> wrote: > Greetings. Very concerned as I am already very,very overweight ("obese" > to be precise) and all of the meds seem to slow down metabolism...have > been on Cymbalta and cannot ascertain its weight gaininig potential yet > but suspect it maybe, excuse me here, very constipating and therefore > contributing to weight gain. Any weight loss and/or gain experiences > with Cymbalta? > I have been on Cymbalta since mid-August, and for me it works as an appetite suppressant. When I first started on it, I nearly had to remind myself to eat for the first week. This passed shortly thereafter, however, there is still a moderate appetite suppressant effect even now. I take either 60 or 90 mg/day of Cymbalta, depending how I feel. The initial *target dose* for Cymbalta is 60 mg., but people can eventually move to a higher dose, up to 120 mg. I don't know about folks having a higher dose than that. It is supposed to have a stronger reuptake inhibition effect on serotonin and norepinepherine than Effexor XR--this is from my personal reading of the prescribing notes, and from my recent Psych course knowledge this fall. I'm sure someone else who may know more about the pharmco issues will chime in as necessary. Like anything else, YMMV--for me, I've lost 8 lbs since mid-August on Cymbalta, with actually a *decrease* in exercise level. I agree, the med is very constipating, I eat lots of prunes, and also have a prescription concoction called Lactolose I also use on occasion. Still, I gained over 20 lbs on Effexor XR, so this is an improvement in my mind. Hope this helps-- Jean in VA
From: culprit on 28 Dec 2005 13:36 "Jeff" <reedgw(a)adelphia.net> wrote in message news:1135740531.866873.10740(a)g14g2000cwa.googlegroups.com... > Greetings. Very concerned as I am already very,very overweight ("obese" > to be precise) and all of the meds seem to slow down metabolism...have > been on Cymbalta and cannot ascertain its weight gaininig potential yet > but suspect it maybe, excuse me here, very constipating and therefore > contributing to weight gain. Any weight loss and/or gain experiences > with Cymbalta? > yup. i gained a bunch of weight on cymbalta, which is weird, because it's not supposed to be a big weight gain med. i found i did much better on Effexor, which is somewhat similar, without gaining any weight.. -kelly
From: Dave on 30 Dec 2005 15:15
Jeff wrote: > Greetings. Very concerned as I am already very,very overweight ("obese" > to be precise) and all of the meds seem to slow down metabolism...have > been on Cymbalta and cannot ascertain its weight gaininig potential yet > but suspect it maybe, excuse me here, very constipating and therefore > contributing to weight gain. Any weight loss and/or gain experiences > with Cymbalta? > Consider selegiline and/or modafinil instead. Neither one of those suffer from that drawback. They are, however, predisposed to causing enhanced cognition and mental clarity, a side-effect seldom seen with serotonin uptake inhibitors. |