From: Sanjay on
http://www.washingtonpost.com/wp-dyn/content/article/2008/08/12/AR200808120
0962.html

Weight Loss After Diabetes Diagnosis Offers Big Benefits: Study

By Amanda Gardner
HealthDay Reporter
Tuesday, August 12, 2008; 12:00 AM

TUESDAY, Aug. 12 (HealthDay News) -- Newly diagnosed type 2 diabetics who
lose weight soon after their diagnosis gain better control of their blood
pressure and blood sugar, a benefit that lasts even if they regain that
weight.

"If you lose weight after diagnosis, you can achieve some long-term
benefits in terms of blood pressure and glycemic control that extend even
beyond the point at which you regain weight," said Gregory A. Nichols,
co-author of new research published online Aug. 12 in the journalDiabetes
Care.

Added Dr. Spyros Mezitis, an endocrinologist with Lenox Hill Hospital in
New York City: "We haven't had results like this before. This is telling us
that with a significant mean weight loss of 10.7 kilograms [23.5 pounds] in
18 months, there's an improvement despite weight regain after 36 months."

More than 20 million Americans now have type 2 diabetes, and the majority
are either overweight or obese.

Studies have shown that weight loss is important to maintain blood-sugar
and blood-pressure control, as well as to keep cholesterol levels in check.
These parameters, in turn, are critical for avoiding the long-term
complications of diabetes, such as heart disease, blindness, kidney damage,
amputations and even death.

Nichols, an investigator with the Kaiser Permanente Center for Health
Research in Portland, Ore., and his team looked at electronic medical
records, spanning 1997 to 2002, for 2,574 patients aged 21 through 75 who
had been recently diagnosed with type 2 diabetes. The participants were
grouped into weight loss categories and followed for four years.

Just over 12 percent of the participants were in the "weight loss" group,
with a mean weight loss of more than 25 pounds. Almost all of those pounds
were regained by 36 months. The other groups were labeled as "higher stable
weight," "lower stable weight" or "weight gain."

Patients who lost weight were more likely to reach blood pressure and blood
sugar targets during the fourth year, although, by then, they had regained
the weight.

The researchers acknowledged, however, that they don't know what happens
after the four-year mark, and they don't know why the benefit was
sustained. "It's entirely possible that one of the explanations here is
that if we looked at 15 years, we wouldn't find that benefit continuing,"
Nichols said.

Nichols and his colleagues hope to explore a number of other questions,
including whether there was a difference in benefit between people who
regained weight and those who kept it off.

Whatever the final answers, "losing weight is a good idea, even if you
regain it," Nichols said.

Said Mezitis: "We do ask that those diabetics who are overweight lose
weight, and that, in general, improves all the factors that affect vascular
disease, and that's blood pressure, blood sugar and cholesterol."



From: Robert Miles on

"Sanjay" <sanjay(a)yourhealth.com> wrote in message
news:20080813110552.340094E5F4(a)outpost.zedz.net...
> http://www.washingtonpost.com/wp-dyn/content/article/2008/08/12/AR200808120
> 0962.html
>
> Weight Loss After Diabetes Diagnosis Offers Big Benefits: Study
>
> By Amanda Gardner
> HealthDay Reporter
> Tuesday, August 12, 2008; 12:00 AM
>
[snip]

True for those who also need to lose weight, which doesn't include all
type 2 diabetics. Type 1 diabetics are likely to have lost too much
weight before diagnosis.

Your URL was split, so I put it back together:

<http://www.washingtonpost.com/wp-dyn/content/article/2008/08/12/AR2008081200962.html>

A web page for the alt.support.diabetes newsgroup, where a number
of type 2 diabetics have found that a low carb diet has the side
effect of helping them lose weight:

http://www.alt-support-diabetes.org/NewlyDiagnosed.htm


From: Mxsmanic on
Sanjay writes:

> Weight Loss After Diabetes Diagnosis Offers Big Benefits: Study

For people who are significantly obese, you can shorten that to "Weight Loss
Offers Big Benefifts."

There's a lot of individuality in body reactions to obesity. Some people can
weigh 400 pounds and not suffer any significant health problems; others may
start moving towards diabetes and hypertension and joint problems and other
things just from being 30-40 pounds overweight--their bodies don't like
obesity and can't handle it safely.
From: Chris Malcolm on
In alt.support.diabetes Sanjay <sanjay(a)yourhealth.com> wrote:
> http://www.washingtonpost.com/wp-dyn/content/article/2008/08/12/AR200808120
> 0962.html

> Weight Loss After Diabetes Diagnosis Offers Big Benefits: Study

> By Amanda Gardner
> HealthDay Reporter
> Tuesday, August 12, 2008; 12:00 AM

> TUESDAY, Aug. 12 (HealthDay News) -- Newly diagnosed type 2 diabetics who
> lose weight soon after their diagnosis gain better control of their blood
> pressure and blood sugar, a benefit that lasts even if they regain that
> weight.

> "If you lose weight after diagnosis, you can achieve some long-term
> benefits in terms of blood pressure and glycemic control that extend even
> beyond the point at which you regain weight," said Gregory A. Nichols,
> co-author of new research published online Aug. 12 in the journalDiabetes
> Care.

[snip]

> Patients who lost weight were more likely to reach blood pressure and blood
> sugar targets during the fourth year, although, by then, they had regained
> the weight.

> The researchers acknowledged, however, that they don't know what happens
> after the four-year mark, and they don't know why the benefit was
> sustained. "It's entirely possible that one of the explanations here is
> that if we looked at 15 years, we wouldn't find that benefit continuing,"
> Nichols said.

They seem puzzled by this effect. Yet it is well known that when you
lose weight you don't just lose fat, you also lose some muscle tissue,
some liver, and in general a little of everything inessential because
the triggers for apoptosis (cell death) become more sensitive during
weight loss. The effect of that is that in all those places where cell
death occurs, there will be a preferential bias towards loss of those
cells which weren't feeling too well, i.e., were no longer working in
an entirely efficient and healthy fashion.

That's why when you lose weight you not only lose fat but also improve
general health more than just as a simple consequence of not being so
heavy.

Then later when you put the weight back on you put it on in terms of
partly extra fat and also regeneration of some of the other losses,
such as liver and muscle tissue. So after you have lost weight and
then regained it you will also have replaced some of your old slightly
diseased cells with some new fresh ones. So although you're now back
at the same old weight, the body is nevertheless a bit fresher and
tuned up.

One of the reasons why regular episodes of fasting and weight loss,
such as the annual fasts advised by some religions, are good for your
health.

--
Chris Malcolm cam(a)infirmatics.ed.ac.uk DoD #205
IPAB, Informatics, JCMB, King's Buildings, Edinburgh, EH9 3JZ, UK
[http://www.dai.ed.ac.uk/homes/cam/]

From: Alan S on
On Wed, 13 Aug 2008 21:24:39 +0200, Mxsmanic
<mxsmanic(a)gmail.com> wrote:

>Sanjay writes:
>
>> Weight Loss After Diabetes Diagnosis Offers Big Benefits: Study
>
>For people who are significantly obese, you can shorten that to "Weight Loss
>Offers Big Benefifts."
>
>There's a lot of individuality in body reactions to obesity. Some people can
>weigh 400 pounds and not suffer any significant health problems; others may
>start moving towards diabetes and hypertension and joint problems and other
>things just from being 30-40 pounds overweight--their bodies don't like
>obesity and can't handle it safely.

What are you doing here mixi? Are you a diabetic? I've only
seen you in the travel groups before.

Cheers, Alan, T2, Australia.
--
Everything in Moderation - Except Laughter.
Blog http://loraldiabetes.blogspot.com
DLife column http://tinyurl.com/5v74xr
http://loraltravel.blogspot.com (Food, Glorious Food in India)