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From: dr2354 on 6 Aug 2008 22:02
I've been on and off this group for the past 6 years.
RRP in May 2003 - SV involvement and positive margins
CALGB study - Mitoxantore, Zoladex, Predisone, Casodex
That brought my PSA down to < 0.003 and gave me all the well published side
effects.
About 18 months ago my PSA began to rise again.
My PSADT had hovered around 3 months.
As my PSA approached "biochemical recurrance" I looked for solutions.
I came across this trial at RPCI.
My PSA was:
..52 on Apr 25 began 10,000 IU per day
..60 on May 19
..73 on Jun 13
..60 on Jul 31

This is a phase II trial and they are looking for more participants.

Hey - it is worth a try

DanR



From: Steve Kramer on 7 Aug 2008 16:11
"dr2354" <danielreynolds(a)comcast.net> wrote in message
news:eNWdnWHV8JsmygfVnZ2dnUVZ_hadnZ2d(a)comcast.com...
> I've been on and off this group for the past 6 years.
> RRP in May 2003 - SV involvement and positive margins
> CALGB study - Mitoxantore, Zoladex, Predisone, Casodex
> That brought my PSA down to < 0.003 and gave me all the well published
> side effects.
> About 18 months ago my PSA began to rise again.
> My PSADT had hovered around 3 months.
> As my PSA approached "biochemical recurrance" I looked for solutions.
> I came across this trial at RPCI.
> My PSA was:
> .52 on Apr 25 began 10,000 IU per day
> .60 on May 19
> .73 on Jun 13
> .60 on Jul 31

I'm only taking 2000 a day. Are they checking anything else for levels that
might elevate or lessen due to the Vit D?




--
PSA 16 10/17/2000 @ 46
Biopsy 11/01/2000 G7 (3+4), T2c
RRP 12/15/2000 G7 (3+4), T3cN0M0 Neg margins
PSA <.1 <.1 <.1 .27 .37 .75 PSAD 0.19 years
EBRT 05-07/2002 @ 47
PSA .34 .22 .15 .21 .32 PSAD .056 years
Lupron 07/03 (1 mo) 8/03 and every 4 months there after
PSA .07 .05 .06 .09 .08 .132 .145 PSAD 1.4 years
Casodex added daily 07/06
PSA <0.04, <0.05, <0.04, <0.04, <0.1 2/12/08
Illegitimati non carborundum


From: Alan Meyer on 9 Aug 2008 22:36
dr2354 wrote:
> I've been on and off this group for the past 6 years.
> RRP in May 2003 - SV involvement and positive margins
> CALGB study - Mitoxantore, Zoladex, Predisone, Casodex
> That brought my PSA down to < 0.003 and gave me all the well published side
> effects.
> About 18 months ago my PSA began to rise again.
> My PSADT had hovered around 3 months.
> As my PSA approached "biochemical recurrance" I looked for solutions.
> I came across this trial at RPCI.
> My PSA was:
> .52 on Apr 25 began 10,000 IU per day
> .60 on May 19
> .73 on Jun 13
> .60 on Jul 31

Dan,

Do you have any stats for a comparable period before April 25?

It would be instructive to look at the difference. However, over
such a short period it's hard to draw any conclusions. There is
said to be a normal variation in PSA from day to day which can
be "as much as 30%", though I don't really know what that means.

> This is a phase II trial and they are looking for more participants.
>
> Hey - it is worth a try
>
> DanR

Sure does look like it's worth a try.

Whether it works or not, please keep us posted.

Thanks.

Alan
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