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From: ironjustice on 3 Oct 2007 10:14
J Chin Med Assoc. 2007 Sep;70(9):357-60.
Novel aspects of vitamin C in epoetin response.
Tarng DC.
Department of Physiology and Institute of Clinical Medicine, National
Yang-Ming University School of Medicine, and Division of Nephrology,
Department of Medicine, Taipei Veterans General Hospital, Taipei,
Taiwan, R.O.C.

Provision of sufficient available iron is a prerequisite to ensure the
bodys optimal response to recombinant human erythropoietin (epoetin).
Functional iron deficiency (a state when iron supply is reduced to
meet the demands for increased erythropoiesis) is a common cause of
poor response to epoetin in dialysis patients who have normal iron
status, even when they are iron-overloaded. Iron supplementation is
not justified for this hyporesponsiveness in patients with iron
overload due to the potential hazards of iron overload aggravated by
intravenous iron therapy. Furthermore, in vivo studies have indicated
that the promising effect of intravenous iron medication to overcome
iron-deficient erythropoiesis is not observed in iron-overloaded
hemodialysis (HD) patients. Vitamin C, a water-soluble antioxidant as
well as a reducing agent, has a number of associations with iron
metabolism. Recent research highlights that vitamin C can potentiate
the mobilization of iron from inert tissue stores and facilitates the
incorporation of iron into protoporphyrin in HD patients being treated
with epoetin. Interest has turned towards the use of vitamin C as an
adjuvant therapy in this field. This review focuses on the improvement
of epoetin response by administration of vitamin C and discusses its
clinical implications and potential issues for internal medicine
doctors.

PMID: 17908648 [PubMed - in process]


Who loves ya.
Tom


Jesus Was A Vegetarian!
http://jesuswasavegetarian.7h.com


Man Is A Herbivore!
http://tinyurl.com/a3cc3


DEAD PEOPLE WALKING
http://tinyurl.com/zk9fk

From: trigonometry1972 on 5 Oct 2007 04:39
So are we to assume, you feel taking vitamin C
is a good thing, Tom?

That is what I get from the abstract.

Be nice Tom. Remember the comment you
make "who loves ya" is a comment of
the pimp to his prostitute meaning no one
loves you. Is that how you feel Tom/Ironinjustice?

From: ironjustice on 5 Oct 2007 08:54
On Oct 5, 1:39 am, trigonometry1...(a)gmail.com wrote:
So are we to assume, you feel taking vitamin C
is a good thing, Tom?
That is what I get from the abstract.
<<

"Furthermore, in vivo studies have indicated
that the promising effect of intravenous iron medication to overcome
iron-deficient erythropoiesis is not observed in iron-overloaded
hemodialysis (HD) patients."

They admit giving iron to someone with KNOWN iron overload .. and only
DON'T give it .. because it doesn't work and it causes .. damage.

Sooo .. take vitamin C .. ?

Is that what you feel the 'take home message' .. is .. ?

Then you must be .. right ..


Who loves ya.
Tom


Jesus Was A Vegetarian!
http://jesuswasavegetarian.7h.com


Man Is A Herbivore!
http://tinyurl.com/a3cc3


DEAD PEOPLE WALKING
http://tinyurl.com/zk9fk







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