|
Prev: Carbohydrates, Time for A Critical Appraisal
Next: There really is no controversy, Adrienne Samuels PhD, letter re evident toxicity of aspartame EJCN 2008.06.11: Murray 2008.06.30
From: Rich Murray on 1 Jul 2008 00:49 There really is no controversy, Adrienne Samuels PhD, letter re evident toxicity of aspartame EJCN 2008.06.11: Murray 2008.06.30 http://rmforall.blogspot.com/2008_06_01_archive.htm Monday, June 30, 2008 http://groups.yahoo.com/group/aspartameNM/message/1546 ___________________________________________________ "Of course, everyone chooses, as a natural priority, to enjoy peace, joy, and love by helping to find, quickly share, and positively act upon evidence about healthy and safe food, drink, and environment." Rich Murray, MA Room For All rmfor...(a)comcast.net 505-501-2298 1943 Otowi Road, Santa Fe, New Mexico 87505 http://RMForAll.blogspot.com new primary archive http://groups.yahoo.com/group/aspartameNM/messages group with 126 members, 1,546 posts in a public archive http://groups.yahoo.com/group/aspartame/messages group with 1,120 members, 22,777 posts in public archive ___________________________________________________ Letter to the Editor European Journal of Clinical Nutrition advance online publication 11 June 2008; doi: 10.1038/ejcn.2008.38 There really is no controversy A Samuels, Solana Beach, CA, USA Correspondence: A Samuels, E-mail: adieo...(a)aol.com; It is noted in the excellent review by Humphries et al. (2008) that debate [over safety] still continues 20 years after the FDA had approved the use of aspartame. Regarding that debate, the following comments are in order. "Aspartame has never been shown to be safe for human consumption." "Aspartame was discovered in 1965. Required safety testing began in 1967. To date, no research outside of the aspartame industry has found aspartame to be safe for human consumption." "In June 1979, the US Food and Drug Administration (FDA) established a Public Board of Inquiry (PBOI) to rule on aspartame safety issues. The PBOI concluded that NutraSweet/aspartame should not be approved pending further investigations of brain tumors in animals." "In 1981, Ronald Reagan became President of the United States; Arthur Hull Hayes Jr was named FDA Commissioner; a Commissioner's panel was established to review issues raised by the PBOI; the panel advised against approval of aspartame; Hayes overruled the PBOI, ignored the recommendations of his own internal FDA team and approved aspartame for use in dry products." "The so-called aspartame-industry 'science' is flawed to the point of being worthless." "Controversy about the safety of aspartame is a device used by those who profit from production and sale of the product. Industry sponsored studies referring to brain damage draw conclusions without basis. Illustrating this practice is a 1980 study which reads, in part, "On the basis of blood absorption curves...[ it] is concluded that (aspartame)...does not result in hypothalamic damage in the newborn monkey (Reynolds et al., 1980)"." "Using techniques similar to those of the glutamate industry (Samuels, 1999), the aspartame industry, in studies of adverse reactions, has manipulated subjects, procedures and statistics to enable researchers to draw the conclusion that there is no significant difference in reactions following ingestion of aspartame as opposed to ingestion of placebo. The study of Geha et al., 1993 illustrates the point." "The FDA gives every appearance of cooperating with the aspartame industry in promoting the 'safety' of aspartame." "Badly flawed industry sponsored studies have gone unchallenged." "Following the unwarranted approval of aspartame, the FDA Adverse Reactions Monitoring System began receiving, and accepting, unsolicited reports of reactions to aspartame. A 26 June 1997 Memorandum from Technical Information Specialist (HFS-728) to Health Hazard Evaluation Board reported that the FDA has received 7259 complaints of adverse reactions attributed to the use of aspartame." "The FDA has a history of minimizing the extent and severity of adverse reactions to food. Reports of debilitating or life-threatening reactions are not routinely investigated, and reports of 'death,' for example, are listed as 'other.' " "In the late 1990s, the FDA stopped accepting reports of adverse reactions to aspartame." In conclusion, Humphries et al., 2008 suggested that 'serious further testing and research be undertaken to eliminate any and all controversies surrounding this product'. It is suggested, rather, that with thoughtful analysis of the industry sponsored studies, it will become abundantly clear that no legitimate controversy about aspartame's toxic potential exists. References 1. Geha R, Buckley CE, Greenberger P, Patterson R, Polmar S, Saxon A et al. (1993). Aspartame is no more likely than placebo to cause urticaria/angioedema: results of a multicenter, randomized, double-blind, placebo-controlled, crossover study. J Allergy Clin Immunol 92, 513-520. Article PubMed ChemPort 2. Humphries P, Pretorius E, Naude H (2008). Direct and indirect cellular effects of aspartame on the brain. Eur J Clin Nutr 62, 451-462. Article PubMed ChemPort 3. Reynolds WA, Stegink LD, Filer Jr LJ, Renn E (1980). Aspartame administration to the infant monkey: hypothalamic morphology and plasma amino acid levels. Nat Rec 198, 73-85. ChemPort| 4. Samuels A (1999). The toxicity/safety of processed free glutamic acid (MSG): a study in suppression of information. Account Res 6, 259-310. PubMed ___________________________________________________ two aspartame toxicity research studies by Resia Pretorius, U. Pretoria, South Africa, debate with JD Fernstrom: Murray 2008.04.04 http://rmforall.blogspot.com/2008_04_01_archive.htm Friday, April 4, 2008 http://groups.yahoo.com/group/aspartameNM/message/1536 two detailed critiques of industry affiliations and biased science in 99 page review with 415 references by BA Magnuson, GA Burdock and 8 more, Critical Reviews in Toxicology, 2007 Sept.: Mark D Gold 13 page: also Rich Murray 2007.09.15: 2008.03.24 http://rmforall.blogspot.com/2008_03_01_archive.htm Monday, March 24, 2008 http://groups.yahoo.com/group/aspartameNM/message/1531 http://www.truthinlabeling.org/ Truth in Labeling Campaign [MSG] Adrienne Samuels, PhD The toxicity/safety of processed free glutamic acid (MSG): a study in suppression of information. Accountability in Research 1999; 6: 259-310. 52-page review adandj...(a)aol.com; adieo...(a)aol.com; http://groups.yahoo.com/group/aspartameNM/message/857 www.dorway.com: original documents and long reviews of flaws in aspartame toxicity research: Murray 2002.07.31 http://groups.yahoo.com/group/aspartameNM/message/858 Samuels: Strong: Roberts: Gold: flaws in double-blind studies re aspartame and MSG toxicity: Murray 2002.08.01 http://www.dorway.com/upipart1.txt http://groups.yahoo.com/group/aspartameNM/message/262 aspartame expose 96K Oct 1987 Part 1/3: Gregory Gordon, UPI reporter: Murray 2000.07.10 http://www.dorway.com/enclosur.html http://groups.yahoo.com/group/aspartameNM/message/53 aspartame history Part 1/4 1964-1976: Gold: Murray 1999.11.06 http://groups.yahoo.com/group/aspartameNM/message/928 revolving door, Monsanto, FDA, EPA: NGIN: Murray 2002.12.23 methanol impurity in alcohol drinks [ and aspartame ] is turned into neurotoxic formic acid, prevented by folic acid, re Fetal Alcohol Syndrome, BM Kapur, DC Lehotay, PL Carlen at U. Toronto, Alc Clin Exp Res 2007 Dec. plain text: detailed biochemistry, CL Nie et al. 2007.07.18: Murray 2008.02.24 http://rmforall.blogspot.com/2008_02_01_archive.htm Sunday, February 24, 2008 http://groups.yahoo.com/group/aspartameNM/message/1524 re "A Few too Many", Joan Acocella, The New Yorker, long review of hangover research 2008.05.26 -- same levels of formaldehyde and formic acid in FEMA trailers and other sources (aspartame, dark wines and liquors, tobacco smoke): Murray 2008.06.05 http://rmforall.blogspot.com/2008_06_01_archive.htm Thursday, June 5, 2008 http://groups.yahoo.com/group/aspartameNM/message/1541 [ formaldehyde and formic acid in FEMA trailers and other sources (aspartame, dark wines and liquors, tobacco smoke): Murray 2008.01.30 http://rmforall.blogspot.com/2008_01_01_archive.htm Wednesday, January 30, 2008 http://groups.yahoo.com/group/aspartameNM/message/1508 The FEMA trailers give about the same amount of formaldehyde and formic acid daily as from a quart of dark wine or liquor, or two quarts (6 12-oz cans) of aspartame diet soda, from their over 1 tenth gram methanol impurity (one part in 10,000), which the body quickly makes into formaldehyde and then formic acid -- enough to be the major cause of "morning after" alcohol hangovers. Methanol and formaldehyde and formic acid also result from many fruits and vegetables, tobacco and wood smoke, heater and vehicle exhaust, household chemicals and cleaners, cosmetics, and new cars, drapes, carpets, furniture, particleboard, mobile homes, buildings, leather... so all these sources add up and interact with many other toxic chemicals. ] http://www.newyorker.com/reporting/2008/05/26/080526fa_fact_acocella?... Annals Of Drinking A Few Too Many Is there any hope for the hung over? by Joan Acocella May 26, 2008 them...(a)newyorker.com "Wayne Jones, of the Swedish National Laboratory of Forensic Medicine" [ http://groups.yahoo.com/group/aspartameNM/message/1469 highly toxic formaldehyde, the cause of alcohol hangovers, is made by the body from 100 mg doses of methanol from dark wines and liquors, dimethyl dicarbonate, and aspartame: Murray 2007.08.31 ] http://groups.yahoo.com/group/aspartameNM/message/1286 methanol products (formaldehyde and formic acid) are main cause of alcohol hangover symptoms [same as from similar amounts of methanol, the 11% part of aspartame]: YS Woo et al, 2005 Dec: Murray 2006.01.20 Addict Biol. 2005 Dec;10(4): 351-5. Concentration changes of methanol in blood samples during an experimentally induced alcohol hangover state. Woo YS, Yoon SJ, Lee HK, Lee CU, Chae JH, Lee CT, Kim DJ. Chuncheon National Hospital, Department of Psychiatry, The Catholic University of Korea, Seoul, Korea. ___________________________________________________ |