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From: PeterB on 7 Feb 2007 16:13
HISTORICAL REVIEW OF CLINICAL TRIALS AT THE OASIS OF HOPE HOSPITAL

Since 1963, one hundred thousand patients have been treated at the
Oasis of Hope Hospital founded by Dr. Ernesto Contreras, Sr.. Patients
have come here from every part of the world seeking cancer therapies
and treatment approaches pioneered by the Contreras doctors,
specifically the Metabolic Therapy . Dr. Contreras called his cancer
therapy "metabolic" because it enhances normal function of organs
while provoking an adverse environment for malignant cells. This is
accomplished through a treatment program that provides detoxification,
natural anti-tumor agents such as laetrile, whole foods and juices,
emotional and spiritual support, and immune stimulation from vitamins,
minerals, phytochemicals and enzymes.

In 1981, we conducted a retrospective study to document the five-year
survival rates of our cancer patients. It is important to note that 95
percent of these patients came to us with stage IV cancers after
conventional therapy had failed to help them. They had been sent home
to die. We treated them with our metabolic therapy and the results
were encouraging. Our overall five-year survival rate for all types of
cancer was 30 percent. We also noted that 86 percent of our patients
outlived their prognosis and reported an improvement in their quality
of life.

Malignancies in the lung, breast, colon and prostate are the most
prevalent in our experience. For this reason, we designed a
prospective study on the efficacy of metabolic therapy focused on
these advanced stage IV cancers. In the table below, we compare our
results against those from clinical trials with conventional
therapies.


Type of cancer / Distant1 Number of patients / 5 yr. survival rate
(%)
Lung Cancer 200 .....................................Oasis:
30% / Conventional: 2%
Breast Cancer 130 .....................................Oasis:
39% / Conventional: 21%
Colon Cancer 150 .....................................Oasis:
30% / Conventional: 8%
Prostate Cancer 600 .....................................Oasis:
86% / Conventional: 33%

1. Distant: A malignant cancer that has spread to parts of the body
remote from the primary tumor either by direct extension or by
discontinuous metastasis to distant organs, tissues, or via the
lymphatic system to distant lymph nodes.

2. Source: American Cancer Society Cancer Facts & Figures 2001

The Oasis statistics when compared to the Conventional statistics are
dramatically better. What makes these results astounding to me is the
difference between the Oasis group and the Conventional group. The
Oasis patients had already undergone surgery, radiation or
chemotherapy. They had endured the hair loss, nausea, burns and
devastation of their energy levels and immune systems. Those in the
Conventional group had no previous treatment to damage their general
condition. They had a fresh start. We can only speculate on the better
results we could achieve with patients that would avoid conventional
therapy before they arrive to the Oasis of Hope.

In spite of the impressive results, our studies were rejected by all
peer reviewed medical journals. The only studies that these groups
recognize are single drug double blind clinical trials. Our study just
didn't meet those criteria. In fact, our results depend on a
combination of therapies. This makes it difficult to single out one
active agent, and this is the objective of cancer research. Scientists
want to identify the means and we have focused completely on the end
result.

Our results in lung cancer were so dramatic however that one group of
oncological authorities did invite us to make a presentation at the
World Congress on Cancer in Buenos Aires. Unfortunately, the Congress
coordinators canceled our participation at the last minute due to
opposition from some outspoken doctors. Once again, those who insisted
that the results were secondary and that our study did not adhere to
their guidelines were able to silence us.

In the past, financial restraints and negativity from the oncological
community have hindered us from conducting standard double blind
clinical trials. But the legal and medical environment is changing as
more and more people demand access to alternative medicine. The
governments in the USA and Mexico have already established offices of
alternative medicine in their health departments. The Ministry of
Health in Mexico has approved our application for a clinical research
organization (CRO) and we are now positioning ourselves for research
grants. We intend to conduct the necessary trials to publish the
results in an effort to make valid therapies available to people in
any part of the world.

We have never been on a crusade to prove the value of alternative
therapies. In fact, we have often been criticized for our use of
conventional medicine. We keep focused on our ultimate goal, the total
well being of our patients. We try not to limit our patients to either
alternative or orthodox therapies. We offer them what are the most
effective and least harmful options. Our approach compliments
conventional medicine with natural elements and mind/spirit support.
To our critics who wage that we do not utilize pure science, we would
like to remind them. Medicine is much more than science, it is a
healing art.

(c) 2005 Oasis of Hope Hospital, All Right Reserved

http://www.oasisofhope.com/clinical_results.html

From: spamfree on 7 Feb 2007 22:52
On 7 Feb 2007 13:13:19 -0800, "PeterB" <pkm(a)mytrashmail.com> wrote:

>HISTORICAL REVIEW OF CLINICAL TRIALS AT THE OASIS OF HOPE HOSPITAL
>
>Since 1963, one hundred thousand patients have been treated at the
>Oasis of Hope Hospital founded by Dr. Ernesto Contreras, Sr.. Patients
>have come here from every part of the world seeking cancer therapies
>and treatment approaches pioneered by the Contreras doctors,
>specifically the Metabolic Therapy . Dr. Contreras called his cancer
>therapy "metabolic" because it enhances normal function of organs
>while provoking an adverse environment for malignant cells. This is
>accomplished through a treatment program that provides detoxification,
>natural anti-tumor agents such as laetrile, whole foods and juices,
>emotional and spiritual support, and immune stimulation from vitamins,
>minerals, phytochemicals and enzymes.
>
>In 1981, we conducted a retrospective study to document the five-year
>survival rates of our cancer patients. It is important to note that 95
>percent of these patients came to us with stage IV cancers after
>conventional therapy had failed to help them. They had been sent home
>to die. We treated them with our metabolic therapy and the results
>were encouraging. Our overall five-year survival rate for all types of
>cancer was 30 percent. We also noted that 86 percent of our patients
>outlived their prognosis and reported an improvement in their quality
>of life.
>
>Malignancies in the lung, breast, colon and prostate are the most
>prevalent in our experience. For this reason, we designed a
>prospective study on the efficacy of metabolic therapy focused on
>these advanced stage IV cancers. In the table below, we compare our
>results against those from clinical trials with conventional
>therapies.
>
>
>Type of cancer / Distant1 Number of patients / 5 yr. survival rate
>(%)
>Lung Cancer 200 .....................................Oasis:
>30% / Conventional: 2%
>Breast Cancer 130 .....................................Oasis:
>39% / Conventional: 21%
>Colon Cancer 150 .....................................Oasis:
>30% / Conventional: 8%
>Prostate Cancer 600 .....................................Oasis:
>86% / Conventional: 33%
>
>1. Distant: A malignant cancer that has spread to parts of the body
>remote from the primary tumor either by direct extension or by
>discontinuous metastasis to distant organs, tissues, or via the
>lymphatic system to distant lymph nodes.
>
>2. Source: American Cancer Society Cancer Facts & Figures 2001
>
>The Oasis statistics when compared to the Conventional statistics are
>dramatically better. What makes these results astounding to me is the
>difference between the Oasis group and the Conventional group. The
>Oasis patients had already undergone surgery, radiation or
>chemotherapy. They had endured the hair loss, nausea, burns and
>devastation of their energy levels and immune systems. Those in the
>Conventional group had no previous treatment to damage their general
>condition. They had a fresh start. We can only speculate on the better
>results we could achieve with patients that would avoid conventional
>therapy before they arrive to the Oasis of Hope.
>
>In spite of the impressive results, our studies were rejected by all
>peer reviewed medical journals. The only studies that these groups
>recognize are single drug double blind clinical trials. Our study just
>didn't meet those criteria. In fact, our results depend on a
>combination of therapies. This makes it difficult to single out one
>active agent, and this is the objective of cancer research. Scientists
>want to identify the means and we have focused completely on the end
>result.
>
>Our results in lung cancer were so dramatic however that one group of
>oncological authorities did invite us to make a presentation at the
>World Congress on Cancer in Buenos Aires. Unfortunately, the Congress
>coordinators canceled our participation at the last minute due to
>opposition from some outspoken doctors. Once again, those who insisted
>that the results were secondary and that our study did not adhere to
>their guidelines were able to silence us.
>
>In the past, financial restraints and negativity from the oncological
>community have hindered us from conducting standard double blind
>clinical trials. But the legal and medical environment is changing as
>more and more people demand access to alternative medicine. The
>governments in the USA and Mexico have already established offices of
>alternative medicine in their health departments. The Ministry of
>Health in Mexico has approved our application for a clinical research
>organization (CRO) and we are now positioning ourselves for research
>grants. We intend to conduct the necessary trials to publish the
>results in an effort to make valid therapies available to people in
>any part of the world.
>
>We have never been on a crusade to prove the value of alternative
>therapies. In fact, we have often been criticized for our use of
>conventional medicine. We keep focused on our ultimate goal, the total
>well being of our patients. We try not to limit our patients to either
>alternative or orthodox therapies. We offer them what are the most
>effective and least harmful options. Our approach compliments
>conventional medicine with natural elements and mind/spirit support.
>To our critics who wage that we do not utilize pure science, we would
>like to remind them. Medicine is much more than science, it is a
>healing art.
>
>(c) 2005 Oasis of Hope Hospital, All Right Reserved
>
>http://www.oasisofhope.com/clinical_results.html

And was this nifty litle piece of self promotion actually published
anywhere other than in-house?

jack
From: Peter Moran on 8 Feb 2007 15:14

http://members.bordernet.com.au/~pmoran/cancer/Showing_it_works_1.htm

What's so hard About showing That a cancer cure works?

A manual for those who Think they've got one! (Part 1)

Let's assume that there are "alternative" cancer cures out there that work
as claimed, and you've got one of them. How to get it recognized?

One matter needs clearing up from the start. It is quite true that those
providing "alternative" cancer treatments don't usually have the resources
to test them out in randomized controlled trials (RCTs - studies where
patients are randomly allotted to differently managed groups and the results
compared. The control group acts rather like the "blank" in a test tube
experiment). It is also true that such trials are the only reliable way
showing activity for many kinds of medical treatment, for example pain
relievers or antidepressants.

Is this why so many cancer cures are being ignored by the medical
profession? Their discoverers simply cannot produce "the kind of evidence
the doctors want?"

Well, despite this fairly standard complaint from many promoters of dubious
cancer treatments, RCTs are definitely NOT the only possible next step up
from usually third-rate testimonial!!.

The truth is that RCTs are not even used in conventional oncology when
initially assessing cancer treatments. This comes as a surprise even to
some skeptics! New cancer treatments are always initially tested for their
ability to produce regression of cancer in patients with measurable cancer
in very simple uncontrolled studies ( Phase 1 and :Phase 11 studies), just
as similar patients might walk into an "alternative" cancer practice
An example of a simple Phase 1/11 study, one that strongly suggests a useful
treatment effect for a dendritic cell vaccine in advanced melanoma,
follows. There are other examples among the references below [7-11]. Are
similar studies too much to ask of the promoters of "alternative" methods?

"Dr Joseph Fay, from the Baylor Institute for Immunology Research in Dallas,
outlined the results of a dendritic cell vaccine in patients with
elanoma. ----------- Five of the 18 patients in this study had a complete
response (CR) to vaccine treatment alone. Two additional patients achieved a
CR after additional vaccinations and surgery. Seven patients are alive at a
median of 39 months from the start of the study. Interestingly, responses
were seen in patients with liver and brain metastasis." (Fay J, Palucka K,
and Banchereau J, Dendritic Cells and Induction of Immunity Against Cancer.
Conference on the Development of Therapeutic Cancer Vaccines, Los Angeles CA
April 27-29, 2008.)

RCTs are of vital importance to oncology but they come into play at a later
stage, when treatments with known activity against cancer are compared to
find out which works best.

Simple forms of evidence such as the above can carry considerable weight in
cancer treatment for one simple reason: cancer is, in general, very
predictable. In the absence of effective treatment it is nearly always a
progressive condition. Thus, so long as the initial state of cancer is
accurately known and the treatment effect is obvious, each patient can act
as their own "control" (comparison case). This does NOT apply with
subjective symptoms such as pain or depression or even with the symptoms
that cancers can cause. They can fluctuate markedly in severity over a
matter of hours. They can also appear to be responsive to sham treatment
(placebo), for complex reasons related to non-specific patient reactions to
medical care and biases in the reporting and observing of complaints.


From: PeterB on 8 Feb 2007 16:19
On Feb 8, 3:14 pm, "Peter Moran" <pmo...(a)bordernet.com.au> wrote:
> http://members.bordernet.com.au/~pmoran/cancer/Showing_it_works_1.htm
>
> What's so hard About showing That a cancer cure works?

Apparently everything, judging by the studies you provided on
chemotherapy earlier. If your defense of the drug makers was
meaningful, these studies would have asked the hard questions,
performed meaningful RCTs, made patient outcomes, rather than tumor
reduction, the premise for its claims, and reported the numbers.
That, Dr. Doolittle, has never happened.

> A manual for those who Think they've got one! (Part 1)
>
> Let's assume that there are "alternative" cancer cures out there that work
> as claimed, and you've got one of them. How to get it recognized?
>
> One matter needs clearing up from the start. It is quite true that those
> providing "alternative" cancer treatments don't usually have the resources
> to test them out in randomized controlled trials (RCTs - studies where
> patients are randomly allotted to differently managed groups and the results
> compared. The control group acts rather like the "blank" in a test tube
> experiment). It is also true that such trials are the only reliable way
> showing activity for many kinds of medical treatment, for example pain
> relievers or antidepressants.
>
> Is this why so many cancer cures are being ignored by the medical
> profession? Their discoverers simply cannot produce "the kind of evidence
> the doctors want?"
>
> Well, despite this fairly standard complaint from many promoters of dubious
> cancer treatments, RCTs are definitely NOT the only possible next step up
> from usually third-rate testimonial!!.
>
> The truth is that RCTs are not even used in conventional oncology when
> initially assessing cancer treatments. This comes as a surprise even to
> some skeptics! New cancer treatments are always initially tested for their
> ability to produce regression of cancer in patients with measurable cancer
> in very simple uncontrolled studies ( Phase 1 and :Phase 11 studies), just
> as similar patients might walk into an "alternative" cancer practice
> An example of a simple Phase 1/11 study, one that strongly suggests a useful
> treatment effect for a dendritic cell vaccine in advanced melanoma,
> follows. There are other examples among the references below [7-11]. Are
> similar studies too much to ask of the promoters of "alternative" methods?
>
> "Dr Joseph Fay, from the Baylor Institute for Immunology Research in Dallas,
> outlined the results of a dendritic cell vaccine in patients with
> elanoma. ----------- Five of the 18 patients in this study had a complete
> response (CR) to vaccine treatment alone. Two additional patients achieved a
> CR after additional vaccinations and surgery. Seven patients are alive at a
> median of 39 months from the start of the study. Interestingly, responses
> were seen in patients with liver and brain metastasis." (Fay J, Palucka K,
> and Banchereau J, Dendritic Cells and Induction of Immunity Against Cancer.
> Conference on the Development of Therapeutic Cancer Vaccines, Los Angeles CA
> April 27-29, 2008.)
>
> RCTs are of vital importance to oncology but they come into play at a later
> stage, when treatments with known activity against cancer are compared to
> find out which works best.
>
> Simple forms of evidence such as the above can carry considerable weight in
> cancer treatment for one simple reason: cancer is, in general, very
> predictable. In the absence of effective treatment it is nearly always a
> progressive condition. Thus, so long as the initial state of cancer is
> accurately known and the treatment effect is obvious, each patient can act
> as their own "control" (comparison case). This does NOT apply with
> subjective symptoms such as pain or depression or even with the symptoms
> that cancers can cause. They can fluctuate markedly in severity over a
> matter of hours. They can also appear to be responsive to sham treatment
> (placebo), for complex reasons related to non-specific patient reactions to
> medical care and biases in the reporting and observing of complaints.


From: Peter Moran on 8 Feb 2007 20:27

"PeterB" <pkm(a)mytrashmail.com> wrote in message
news:1170969596.175619.223080(a)h3g2000cwc.googlegroups.com...
> On Feb 8, 3:14 pm, "Peter Moran" <pmo...(a)bordernet.com.au> wrote:
>> http://members.bordernet.com.au/~pmoran/cancer/Showing_it_works_1.htm
>>
>> What's so hard About showing That a cancer cure works?
>
> Apparently everything, judging by the studies you provided on
> chemotherapy earlier. If your defense of the drug makers was
> meaningful, these studies would have asked the hard questions,
> performed meaningful RCTs, made patient outcomes, rather than tumor
> reduction, the premise for its claims, and reported the numbers.
> That, Dr. Doolittle, has never happened.

Tumour reduction is an essential feature of any active cancer treatment.
Even boosting the immune system should results in tumour reduction.
Inducing apoptosis should result in tumour reduction.

When it comes to patient outcomes, are you talking about chemotherapy with
curative intent or palliative intent or as an adjuvant ot other measures?
The patient outcomes sought will be different in each case. And regarding
the use of which chemotherapy for which cancers do you say there is no
meaningful evidence? I have previously supplied what evidence is
available in relation to some, supplying ":numbers" as to the various
paramenters measured, and when compared with "best supportive care". Did
you not understand those abstracts? I agree they are difficult for the
average person.

P M . .
>
>> A manual for those who Think they've got one! (Part 1)
>>
>> Let's assume that there are "alternative" cancer cures out there that
>> work
>> as claimed, and you've got one of them. How to get it recognized?
>>
>> One matter needs clearing up from the start. It is quite true that those
>> providing "alternative" cancer treatments don't usually have the
>> resources
>> to test them out in randomized controlled trials (RCTs - studies where
>> patients are randomly allotted to differently managed groups and the
>> results
>> compared. The control group acts rather like the "blank" in a test
>> tube
>> experiment). It is also true that such trials are the only reliable
>> way
>> showing activity for many kinds of medical treatment, for example pain
>> relievers or antidepressants.
>>
>> Is this why so many cancer cures are being ignored by the medical
>> profession? Their discoverers simply cannot produce "the kind of
>> evidence
>> the doctors want?"
>>
>> Well, despite this fairly standard complaint from many promoters of
>> dubious
>> cancer treatments, RCTs are definitely NOT the only possible next step
>> up
>> from usually third-rate testimonial!!.
>>
>> The truth is that RCTs are not even used in conventional oncology when
>> initially assessing cancer treatments. This comes as a surprise even
>> to
>> some skeptics! New cancer treatments are always initially tested for
>> their
>> ability to produce regression of cancer in patients with measurable
>> cancer
>> in very simple uncontrolled studies ( Phase 1 and :Phase 11 studies),
>> just
>> as similar patients might walk into an "alternative" cancer practice
>> An example of a simple Phase 1/11 study, one that strongly suggests a
>> useful
>> treatment effect for a dendritic cell vaccine in advanced melanoma,
>> follows. There are other examples among the references below [7-11].
>> Are
>> similar studies too much to ask of the promoters of "alternative"
>> methods?
>>
>> "Dr Joseph Fay, from the Baylor Institute for Immunology Research in
>> Dallas,
>> outlined the results of a dendritic cell vaccine in patients with
>> elanoma. ----------- Five of the 18 patients in this study had a
>> complete
>> response (CR) to vaccine treatment alone. Two additional patients
>> achieved a
>> CR after additional vaccinations and surgery. Seven patients are alive at
>> a
>> median of 39 months from the start of the study. Interestingly, responses
>> were seen in patients with liver and brain metastasis." (Fay J, Palucka
>> K,
>> and Banchereau J, Dendritic Cells and Induction of Immunity Against
>> Cancer.
>> Conference on the Development of Therapeutic Cancer Vaccines, Los Angeles
>> CA
>> April 27-29, 2008.)
>>
>> RCTs are of vital importance to oncology but they come into play at a
>> later
>> stage, when treatments with known activity against cancer are compared
>> to
>> find out which works best.
>>
>> Simple forms of evidence such as the above can carry considerable weight
>> in
>> cancer treatment for one simple reason: cancer is, in general, very
>> predictable. In the absence of effective treatment it is nearly always
>> a
>> progressive condition. Thus, so long as the initial state of cancer is
>> accurately known and the treatment effect is obvious, each patient can
>> act
>> as their own "control" (comparison case). This does NOT apply with
>> subjective symptoms such as pain or depression or even with the symptoms
>> that cancers can cause. They can fluctuate markedly in severity over a
>> matter of hours. They can also appear to be responsive to sham treatment
>> (placebo), for complex reasons related to non-specific patient reactions
>> to
>> medical care and biases in the reporting and observing of complaints.
>
>


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