Sjogrens
in [Lupus]
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From: Nicole on 18 Dec 2007 13:49 Sj�gren's ("SHOW-grins") syndrome is an autoimmune disease. Autoimmune diseases are characterized by the abnormal production of extra antibodies in the blood that are directed against various tissues of the body. This particular autoimmune illness features inflammation in certain glands of the body. Inflammation of the glands that produce tears (lacrimal glands) leads to decreased water production for tears and eye dryness. Inflammation of the glands that produce the saliva in the mouth (salivary glands, including the parotid glands) leads to mouth dryness. Sj�gren's syndrome with gland inflammation (resulting dry eyes and mouth, etc.) that is not associated with another connective tissue disease is referred to as primary Sj�gren's syndrome. Sj�gren's syndrome that is also associated with a connective tissue disease, such as rheumatoid arthritis, systemic lupus erythematosus, or scleroderma, is referred to as secondary Sj�gren's syndrome. While the exact cause of Sj�gren's syndrome is not known, there is growing scientific support for genetic (inherited) factors. The illness is sometimes found in other family members. It is also found more commonly in families that have members with other autoimmune illnesses, such as systemic lupus erythematosus, autoimmune thyroid disease, juvenile diabetes, etc. 90% of patients with Sj�gren's syndrome are female. www.medicinenet.com Systemic lupus erythematosus (SLE) is also an autoimmune disease. HTH Nicole -- 3 of every 10 Americans Know Someone With Lupus Help find the cure. www.lupus.org
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