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From: Alex on 7 Aug 2005 21:54 My dad has a history of very high PSA, though he has not been diagnosed with the cancer, with 3 negative biopcies - see his PSA history below. He is 68, and looks like he's started losing weight recently. Is weight loss typical for a prostate cancer (I mean, weight loss is probably typical for any very advanced cancer, but he should not have it very advanced based on his PSA) ? 09/94 PSA = 4.9 10/97 PSA = 8.0 11/97 PSA = 12.0 11/97 Negative biopsy 08/99 PSA = 12.6, free PSA = 7.1% (low!) 10/99 Negative biopsy 05/00 PSA = 15.9 01/01 PSA = 13.0 06/01 PSA = 12.4 03/02 PSA = 14.0 10/02 PSA = 20.0, free PSA = 15% 10/02 Negative biopsy 11/02 PSA = 17.8 08/03 PSA = 21.9 10/03 PSA = 23.3 03/04 PSA = 15.6 03/05 PSA = 15.1
From: Ed on 7 Aug 2005 22:23 On 7 Aug 2005 18:54:47 -0700, "Alex" <arazumo(a)hotmail.com> wrote: >My dad has a history of very high PSA, though he has not been diagnosed >with the cancer, with 3 negative biopcies - see his PSA history below. >He is 68, and looks like he's started losing weight recently. Is weight >loss typical for a prostate cancer (I mean, weight loss is probably >typical for any very advanced cancer, but he should not have it very >advanced based on his PSA) ? > >09/94 PSA = 4.9 >10/97 PSA = 8.0 >11/97 PSA = 12.0 >11/97 Negative biopsy >08/99 PSA = 12.6, free PSA = 7.1% (low!) >10/99 Negative biopsy >05/00 PSA = 15.9 >01/01 PSA = 13.0 >06/01 PSA = 12.4 >03/02 PSA = 14.0 >10/02 PSA = 20.0, free PSA = 15% >10/02 Negative biopsy >11/02 PSA = 17.8 >08/03 PSA = 21.9 >10/03 PSA = 23.3 >03/04 PSA = 15.6 >03/05 PSA = 15.1 Pretty tough for us armchair doctors to say. Hasn't he asked his uro? My PSA is 26 and I don't think I have cancer (4 negative biopsies and several negative DREs). Ask someone who is qualified and knows the history. Ed
From: RVer Don on 8 Aug 2005 02:25 "Alex" <arazumo(a)hotmail.com> wrote in message news:1123466087.399671.151600(a)g47g2000cwa.googlegroups.com... > My dad has a history of very high PSA, though he has not been diagnosed > with the cancer, with 3 negative biopcies - see his PSA history below. > He is 68, and looks like he's started losing weight recently. Is weight > loss typical for a prostate cancer (I mean, weight loss is probably > typical for any very advanced cancer, but he should not have it very > advanced based on his PSA) ? > Don't know about the weight loss but does your father suffer from bph? If so, that may be causing the high psa numbers. Prior to having a TURP in 1998 my psa, over a period of several years, went from 4 to 17. I also had two negative biopsies during this time. Following the TURP it dropped back to 4 and has stayed there since. I have never had a reading much less than 4. At the time my uro said that bph could cause higher psa readings. Don
From: Douwe on 8 Aug 2005 03:34 "Alex" <arazumo(a)hotmail.com> wrote... > My dad has a history of very high PSA, though he has not been diagnosed > with the cancer, with 3 negative biopcies - see his PSA history below. > He is 68, and looks like he's started losing weight recently. Is weight > loss typical for a prostate cancer (I mean, weight loss is probably > typical for any very advanced cancer, but he should not have it very > advanced based on his PSA) ? Hi Alex, a PSA of 4 should be 'normal' for a 68 yrs man. 10 isn't very high. (I'm 62 and no history yet, when measured it was 416, I read resently) Yes I do have cancer and I'm gaining weight, because of keeping fluid in, or lymph oedeem or such. A little blood test will give some indication. The thyroid gland is suspect, I think. Douwe
From: Leonard Evens on 8 Aug 2005 09:53
Alex wrote: > My dad has a history of very high PSA, though he has not been diagnosed > with the cancer, with 3 negative biopcies - see his PSA history below. > He is 68, and looks like he's started losing weight recently. Is weight > loss typical for a prostate cancer (I mean, weight loss is probably > typical for any very advanced cancer, but he should not have it very > advanced based on his PSA) ? > > 09/94 PSA = 4.9 > 10/97 PSA = 8.0 > 11/97 PSA = 12.0 > 11/97 Negative biopsy > 08/99 PSA = 12.6, free PSA = 7.1% (low!) > 10/99 Negative biopsy > 05/00 PSA = 15.9 > 01/01 PSA = 13.0 > 06/01 PSA = 12.4 > 03/02 PSA = 14.0 > 10/02 PSA = 20.0, free PSA = 15% > 10/02 Negative biopsy > 11/02 PSA = 17.8 > 08/03 PSA = 21.9 > 10/03 PSA = 23.3 > 03/04 PSA = 15.6 > 03/05 PSA = 15.1 Generally, one would expect a prostate cancer advanced enough to produce weight loss to be detectable on biopsy. But all sorts of strange things happen. For example, it could be that a very small cancer, which is missed on biopsy still managed to metastasize. All this, however, is just conjecture. The weight loss probably doesn't have anything to do with prostate cancer, but since it could indicate something which needs to be treated, he ought to have a thorough medical workup. > |