From: psommerfeld on
For anyone following the use of BMP7 protein for kidney diease:

Curis, after being "disappointed" with J&J lack of progress on BMP7
(read: they did absolutely nothing over the 4.5 years). Curis is now
looking for a new licensee (see
http://seekingalpha.com/article/47830-curis-the-wall-street-analyst-forum-presentation-transcript).

Let's hope and pray that Curis or a new licensee actually develops
this drug into something useful sooner rather than later.

Remember: J&J loves chronically sick patients who depend on their
drug. (Epogen, at $2 bln, from J&J is Medicare's single most expensive
drug cost: http://seekingalpha.com/article/47830-curis-the-wall-street-analyst-forum-presentation-transcript).
Once again greed trumps compassion :(

Info on BMP7:
- http://65.57.249.23/ubb/Forum9/HTML/000152.html
- http://phx.corporate-ir.net/phoenix.zhtml?c=123198&p=irol-newsArticle&ID=505499&highlight=
- http://ndt.oxfordjournals.org/cgi/content/full/19/4/759
- http://ndt.oxfordjournals.org/cgi/content/full/21/3/568
- http://www.pathway2curis.com/bmp-7-ortho-biotech-products-a-subsidiary-of-johnson-johnson-vf11.html

-- Pete

From: psommerfeld on
The second link should be:

http://ageorgialawyer.blogspot.com/2007/04/epogen-study-drug-was-profit-center.html

-- Pete

On Sep 30, 12:27 am, psommerf...(a)gmail.com wrote:
> For anyone following the use of BMP7 protein for kidney diease:
>
> Curis, after being "disappointed" with J&J lack of progress on BMP7
> (read: they did absolutely nothing over the 4.5 years). Curis is now
> looking for a new licensee (seehttp://seekingalpha.com/article/47830-curis-the-wall-street-analyst-f...).
>
> Let's hope and pray that Curis or a new licensee actually develops
> this drug into something useful sooner rather than later.
>
> Remember: J&J loves chronically sick patients who depend on their
> drug. (Epogen, at $2 bln, from J&J is Medicare's single most expensive
> drug cost:http://seekingalpha.com/article/47830-curis-the-wall-street-analyst-f...).
> Once again greed trumps compassion :(
>
> Info on BMP7:
> -http://65.57.249.23/ubb/Forum9/HTML/000152.html
> -http://phx.corporate-ir.net/phoenix.zhtml?c=123198&p=irol-newsArticle...
> -http://ndt.oxfordjournals.org/cgi/content/full/19/4/759
> -http://ndt.oxfordjournals.org/cgi/content/full/21/3/568
> -http://www.pathway2curis.com/bmp-7-ortho-biotech-products-a-subsidiar...
>
> -- Pete


From: mainframetech on
On Sep 30, 12:27 am, psommerf...(a)gmail.com wrote:
> For anyone following the use of BMP7 protein for kidney diease:
>
> Curis, after being "disappointed" with J&J lack of progress on BMP7
> (read: they did absolutely nothing over the 4.5 years). Curis is now
> looking for a new licensee (seehttp://seekingalpha.com/article/47830-curis-the-wall-street-analyst-f...).
>
> Let's hope and pray that Curis or a new licensee actually develops
> this drug into something useful sooner rather than later.
>
> Remember: J&J loves chronically sick patients who depend on their
> drug. (Epogen, at $2 bln, from J&J is Medicare's single most expensive
> drug cost:http://seekingalpha.com/article/47830-curis-the-wall-street-analyst-f...).
> Once again greed trumps compassion :(
>
> Info on BMP7:
> -http://65.57.249.23/ubb/Forum9/HTML/000152.html
> -http://phx.corporate-ir.net/phoenix.zhtml?c=123198&p=irol-newsArticle...
> -http://ndt.oxfordjournals.org/cgi/content/full/19/4/759
> -http://ndt.oxfordjournals.org/cgi/content/full/21/3/568
> -http://www.pathway2curis.com/bmp-7-ortho-biotech-products-a-subsidiar...
>
> -- Pete

Pete,
Thanks for the heads-up. I have followed BMP7 and been very
frustrated by the complete lack of effort to turn it into a going
concern. I wrote and called them and got nowhere. The people they
put on the phone couldn't even figure out inhouse who had any info on
whether they were working on it (probably because there wasn't any).

Yes, I agree that J&J did nothing because there would be
competition with their other moneymaking products, but you have to
also do the addition for a product that works and cures a disease, and
a product that only helps someone keep going without cure. Notice how
many drugs today cause the doctor to say to you "you will have to take
this the rest of your life". What a powerful lot of money that
represents with all the people that take things like kidney
treatments, blood pressure treatments, heart treatments (statins,
etc.) for many years before they go. If they had been cured they
would take a medicine for perhaps a few months instead of years, and
the drug companies would suffer for income.

I was speaking with a pharmacist near me and he brought up the
fact that if drug companies cured people they would have no customers
and would soon go out of business. What a surprise to hear that from
a pharmacist whose income depends on folks needing more drugs. Must
have had a rare altruistic nature.

I'm off to see what the next excuse will be for not moving BMP7
along.

Chris

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