From: ironjustice on
"Porphyria cutanea tarda should be considered for scleroderma"

Nippon Rinsho. 1995 Jun;53(6):1463-7.Links
[Scleroderma and porphyria cutanea tarda][Article in Japanese]


Tsukazaki N, Okada S, Yoshida H.
Department of Dermatology, Nagasaki University School of Medicine.

Examination was made of sclerodermoid changes in porphyria cutanea
tarda (PCT) and PCT in association with true scleroderma. Although
sclerodermoid change in PCT is rare in Japan, it is important in the
diagnosis of PCT when there are few other clinical signs
characteristic of PCT. In the present case, slight improvement in
cutaneous sclerosis was noted following treatment for PCT, but
pulmonary changes somewhat intensified. The reason for the association
of PCT with progressive systemic sclerosis (PSS) remains obscure.
Elevated uroporphyrin due to PCT may possibly increase cutaneous
sclerosis in PSS. A diagnosis of PCT should be considered for patients
presenting scleroderma, since it is difficult to distinguish
sclerodermoid changes from true scleroderma.

PMID: 7616663 [PubMed - indexed for MEDLINE]
Who loves ya.
Tom


Jesus Was A Vegetarian!
http://tinyurl.com/2r2nkh


Man Is A Herbivore!
http://tinyurl.com/a3cc3


DEAD PEOPLE WALKING
http://tinyurl.com/zk9fk
From: ironjustice on
On Jun 17, 11:00 pm, ironjustice <teamtan...(a)hotmail.com>
wrote:Porphyria cutanea tarda <<

Just in case anyone is unaware .. porphyria cutanea tarda is iron
overload.

On Jun 17, 11:00 pm, ironjustice <teamtan...(a)hotmail.com> wrote:
Elevated uroporphyrin due to PCT <<

We also just learned throught the mistaken feeding of fish to mice
that meat causes elevated uroporphyrin.
We also just learned that when the iron is too high the vitamin C in
the body cannot stop the body from having elevated uroporphyrin.

Sooo .. is it the iron overload / porphyria cutanea tarda which is
causing the increased scleroderma in lupus .. ?

Does porphyria cutanea tarda .. share .. many .. ? ..common
symptoms .. ?

We know there is a VERY high rate of anemia .. in lupus.

Which we pretty much have established seems to be kinda .. strange ..
due to the fact .. EVERYONE with 'similar' diseases are in FACT ..
all .. iron OVERLOADED.

Sooo ..if one were to disregard this hyperferritinemia in lupus AS..
not to be recognized .. but just the OPPOSITE and USE this iron
overload marker AS an iron overload marker .. and what are you left
with .. ?

EVERY marker now points to iron overload as a LARGE problem in lupus
as opposed to .. "they are all iron deficient" ..

Just the OPPOSITE of what .. 'they'.. TELL you ..

Scary .. but seems to be true .. by using .. logic.

Hyperferritinemia used as a marker shows iron overload in almost all
SLE patients.

The rest .. ?

Seeing the marker they DO use for hyperferritinemia is SOOOOOO ..
high .. then we can pretty much be sure all the rest are over the low
marker ..

Logical .. ?

Yep ..
Who loves ya.
Tom


Jesus Was A Vegetarian!
http://tinyurl.com/2r2nkh


Man Is A Herbivore!
http://tinyurl.com/a3cc3


DEAD PEOPLE WALKING
http://tinyurl.com/zk9fk



> "Porphyria cutanea tarda should be considered for scleroderma"
>
> Nippon Rinsho. 1995 Jun;53(6):1463-7.Links
> [Scleroderma and porphyria cutanea tarda][Article in Japanese]
>
> Tsukazaki N, Okada S, Yoshida H.
> Department of Dermatology, Nagasaki University School of Medicine.
>
> Examination was made of sclerodermoid changes in porphyria cutanea
> tarda (PCT) and PCT in association with true scleroderma. Although
> sclerodermoid change in PCT is rare in Japan, it is important in the
> diagnosis of PCT when there are few other clinical signs
> characteristic of PCT. In the present case, slight improvement in
> cutaneous sclerosis was noted following treatment for PCT, but
> pulmonary changes somewhat intensified. The reason for the association
> of PCT with progressive systemic sclerosis (PSS) remains obscure.
> Elevated uroporphyrin due to PCT may possibly increase cutaneous
> sclerosis in PSS. A diagnosis of PCT should be considered for patients
> presenting scleroderma, since it is difficult to distinguish
> sclerodermoid changes from true scleroderma.
>
> PMID: 7616663 [PubMed - indexed for MEDLINE]
> Who loves ya.
> Tom
>
> Jesus Was A Vegetarian!http://tinyurl.com/2r2nkh
>
> Man Is A Herbivore!http://tinyurl.com/a3cc3
>
> DEAD PEOPLE WALKINGhttp://tinyurl.com/zk9fk

From: ironjustice on
On Jun 19, 8:48 pm, "ironjust...(a)aol.com" <ironjust...(a)aol.com> wrote:
The reason for the association of PCT with progressive systemic
sclerosis (PSS) remains obscure. <<

Hmmmm .. another case of iron overload and systemic sclerosis ..
This time with siderosis / another iron overload the deafening
disease.

Systemic sclerosis and superficial siderosis of the central nervous
system: casuality or causality?
Rheumatol Int. 2008 Jun;28(8):815-8. Epub 2008 Jan 12
Simeoni S, Puccetti A, Tinazzi E, Tomelleri G, Corrocher R, Lunardi C.
Department of Clinical and Experimental Medicine, Section of Internal
Medicine, University of Verona, Policlinico GB Rossi, Piazzale LA
Scuro, 37134, Verona, Italy.

We describe the case of a 59 year old man with systemic sclerosis and
superficial siderosis of the central nervous system characterized by
progressive worsening of walking with signs of pyramidal liberation
associated with cerebellar ataxia and bilateral hypoacusia.
Ferritin and oligoclonal bands were found on lumbar puncture and
Magnetic Resonance Imaging of the brain and spinal cord revealed a rim
of hypointensity in T2-weighted images enveloping the surface of brain
and spinal cord, typical of hemosiderosis.
Neurological complications, both central and peripheral, are thought
to be rare and coincidental in systemic sclerosis; however over the
past decade, some authors have reported a high incidence (up to 40%)
of neurological involvement in the disease.
In this report we consider the hypothesis that superficial siderosis
may be a direct complication of systemic sclerosis.
To our knowledge, this case represents the first description of
superficial siderosis in a patient with systemic sclerosis.

PMID: 18193230 [PubMed - in process]

Who loves ya.
Tom


Jesus Was A Vegetarian!
http://tinyurl.com/2r2nkh


Man Is A Herbivore!
http://tinyurl.com/a3cc3


DEAD PEOPLE WALKING
http://tinyurl.com/zk9fk


> On Jun 17, 11:00 pm, ironjustice <teamtan...(a)hotmail.com>
> wrote:Porphyria cutanea tarda <<
>
> Just in case anyone is unaware .. porphyria cutanea tarda is iron
> overload.
>
> On Jun 17, 11:00 pm, ironjustice <teamtan...(a)hotmail.com> wrote:
> Elevated uroporphyrin due to PCT <<
>
> We also just learned throught the mistaken feeding of fish to mice
> that meat causes elevated uroporphyrin.
> We also just learned that when the iron is too high the vitamin C in
> the body cannot stop the body from having elevated uroporphyrin.
>
> Sooo .. is it the iron overload / porphyria cutanea tarda which is
> causing the increased scleroderma in lupus .. ?
>
> Does porphyria cutanea tarda .. share .. many .. ? ..common
> symptoms .. ?
>
> We know there is a VERY high rate of anemia .. in lupus.
>
> Which we pretty much have established seems to be kinda .. strange ..
> due to the fact .. EVERYONE with 'similar' diseases are in FACT ..
> all .. iron OVERLOADED.
>
> Sooo ..if one were to disregard this hyperferritinemia in lupus AS..
> not to be recognized .. but just the OPPOSITE and USE this iron
> overload marker AS an iron overload marker .. and what are you left
> with .. ?
>
> EVERY marker now points to iron overload as a LARGE problem in lupus
> as opposed to .. "they are all iron deficient" ..
>
> Just the OPPOSITE of what .. 'they'.. TELL you ..
>
> Scary .. but seems to be true .. by using .. logic.
>
> Hyperferritinemia used as a marker shows iron overload in almost all
> SLE patients.
>
> The rest .. ?
>
> Seeing the marker they DO use for hyperferritinemia is SOOOOOO ..
> high .. then we can pretty much be sure all the rest are over the low
> marker ..
>
> Logical .. ?
>
> Yep ..
> Who loves ya.
> Tom
>
> Jesus Was A Vegetarian!http://tinyurl.com/2r2nkh
>
> Man Is A Herbivore!http://tinyurl.com/a3cc3
>
> DEAD PEOPLE WALKINGhttp://tinyurl.com/zk9fk
>
>
>
> > "Porphyria cutanea tarda should be considered for scleroderma"
>
> > Nippon Rinsho. 1995 Jun;53(6):1463-7.Links
> > [Scleroderma and porphyria cutanea tarda][Article in Japanese]
>
> > Tsukazaki N, Okada S, Yoshida H.
> > Department of Dermatology, Nagasaki University School of Medicine.
>
> > Examination was made of sclerodermoid changes in porphyria cutanea
> > tarda (PCT) and PCT in association with true scleroderma. Although
> > sclerodermoid change in PCT is rare in Japan, it is important in the
> > diagnosis of PCT when there are few other clinical signs
> > characteristic of PCT. In the present case, slight improvement in
> > cutaneoussclerosiswas noted following treatment for PCT, but
> > pulmonary changes somewhat intensified. The reason for the association
> > of PCT with progressivesystemicsclerosis(PSS) remains obscure.
> > Elevated uroporphyrin due to PCT may possibly increase cutaneous
> >sclerosisin PSS. A diagnosis of PCT should be considered for patients
> > presenting scleroderma, since it is difficult to distinguish
> > sclerodermoid changes from true scleroderma.
>
> > PMID: 7616663 [PubMed - indexed for MEDLINE]
> > Who loves ya.
> > Tom
>
> > Jesus Was A Vegetarian!http://tinyurl.com/2r2nkh
>
> > Man Is A Herbivore!http://tinyurl.com/a3cc3
>
> > DEAD PEOPLE WALKINGhttp://tinyurl.com/zk9fk- Hide quoted text -
>
> - Show quoted text -

From: ironjustice on
On Jun 19, 8:48 pm, "ironjust...(a)aol.com" <ironjust...(a)aol.com>
wrote:porphyria cutanea tarda <<

I suppose it is mere coincidence the drug used to treat porphyria
cutanea tarda is very useful in lupus?
No iron overload in lupus like in porphyria cutanea tarda?

"Cutaneous symptoms disappeared"

Arch Dermatol. 1980 Oct;116(10):1147-50.Links
Hydroxychloroquine treatment of porphyria cutanea tarda.
Malkinson FD, Levitt L.
Six patients with skin changes and urinary porphyrin excretion
patterns characteristic for porphyria cutanea tarda were treated with
hydroxychloroquine sulfate therapy.
During treatment periods ranging from five to 13 months, cutaneous
symptoms disappeared and urinary porphyrin excretion abnormalities
were completely or almost completely reversed.
In three subjects, hydroxychloroquine therapy was accompanied by
changes in the urinary excretion of iron.
The first four patients, followed up for nine to 24 months after
treatment, all had relapse, and substantial porphyrinuria developed
once more; cutaneous symptoms recurred in two of these.
Three of the four patients were re-treated, and their conditions again
improved or went into remission with hydroxychloroquine therapy.
In two patients, treatment responses were slower than those initially
seen, despite the use of higher drug doses; in the third patient, the
response to re-treatment was more rapid than that seen during the
first treatment course.

PMID: 7425660 [PubMed - indexed for MEDLINE]
---------------------------------------

http://www.aafp.org/afp/980600ap/petri.html

Treatment of Polyarthritis in Patients with Systemic Lupus
Erythematosus

Drug Comment
NSAIDs Avoid gastrotoxic NSAIDs; counter with cytoprotective therapy
Antimalarials Hydroxychloroquine (Plaquenil) is the antimalarial drug
used most often in the United States; ophthalmologic monitoring is
recommended every six to 12 months
Glucocorticoids Individual joints may benefit from intra-articular
injection of triamcinolone (Aristospan); severe polyarthritis flare-
ups may be treated with intravenous "pulse therapy" consisting of
1,000 mg of methylprednisolone (Solumedrol) daily for three days; use
of prednisone for maintenance therapy should be limited to 10 mg or
less daily
Immunosuppressive
drugs Methotrexate (Rheumatrex) or azathioprine (Imuran) can be used
as steroid-sparing drugs; methotrexate cannot be used during
pregnancy

--------------------------------------------------------------------------------
NSAIDs=nonsteroidal anti-inflammatory drugs.


Antimalarial agents, especially hydroxychloroquine (Plaquenil), are
frequently used in the treatment of polyarthritis. Hydroxychloroquine
is very safe; only 1 percent of patients using it develop retinopathy.
Retinopathy as a result of hydroxychloroquine use is usually
reversible when the drug is discontinued.


Who loves ya.
Tom


Jesus Was A Vegetarian!
http://tinyurl.com/2r2nkh


Man Is A Herbivore!
http://tinyurl.com/4rq595


DEAD PEOPLE WALKING
http://tinyurl.com/zk9fk



> On Jun 17, 11:00 pm, ironjustice <teamtan...(a)hotmail.com>
> wrote:Porphyria cutanea tarda <<
>
> Just in case anyone is unaware .. porphyria cutanea tarda is iron
> overload.
>
> On Jun 17, 11:00 pm, ironjustice <teamtan...(a)hotmail.com> wrote:
> Elevated uroporphyrin due to PCT <<
>
> We also just learned throught the mistaken feeding of fish to mice
> that meat causes elevated uroporphyrin.
> We also just learned that when the iron is too high the vitamin C in
> the body cannot stop the body from having elevated uroporphyrin.
>
> Sooo .. is it the iron overload / porphyria cutanea tarda which is
> causing the increased scleroderma in lupus .. ?
>
> Does porphyria cutanea tarda .. share .. many .. ? ..common
> symptoms .. ?
>
> We know there is a VERY high rate of anemia .. in lupus.
>
> Which we pretty much have established seems to be kinda .. strange ..
> due to the fact .. EVERYONE with 'similar' diseases are in FACT ..
> all .. iron OVERLOADED.
>
> Sooo ..if one were to disregard this hyperferritinemia in lupus AS..
> not to be recognized .. but just the OPPOSITE and USE this iron
> overload marker AS an iron overload marker .. and what are you left
> with .. ?
>
> EVERY marker now points to iron overload as a LARGE problem in lupus
> as opposed to .. "they are all iron deficient" ..
>
> Just the OPPOSITE of what .. 'they'.. TELL you ..
>
> Scary .. but seems to be true .. by using .. logic.
>
> Hyperferritinemia used as a marker shows iron overload in almost all
> SLE patients.
>
> The rest .. ?
>
> Seeing the marker they DO use for hyperferritinemia is SOOOOOO ..
> high .. then we can pretty much be sure all the rest are over the low
> marker ..
>
> Logical .. ?
>
> Yep ..
> Who loves ya.
> Tom
>
> Jesus Was A Vegetarian!http://tinyurl.com/2r2nkh
>
> Man Is A Herbivore!http://tinyurl.com/a3cc3
>
> DEAD PEOPLE WALKINGhttp://tinyurl.com/zk9fk
>
>
>
> > "Porphyria cutanea tarda should be considered for scleroderma"
>
> > Nippon Rinsho. 1995 Jun;53(6):1463-7.Links
> > [Scleroderma and porphyria cutanea tarda][Article in Japanese]
>
> > Tsukazaki N, Okada S, Yoshida H.
> > Department of Dermatology, Nagasaki University School of Medicine.
>
> > Examination was made of sclerodermoid changes in porphyria cutanea
> > tarda (PCT) and PCT in association with true scleroderma. Although
> > sclerodermoid change in PCT is rare in Japan, it is important in the
> > diagnosis of PCT when there are few other clinical signs
> > characteristic of PCT. In the present case, slight improvement in
> > cutaneous sclerosis was noted following treatment for PCT, but
> > pulmonary changes somewhat intensified. The reason for the association
> > of PCT with progressive systemic sclerosis (PSS) remains obscure.
> > Elevated uroporphyrin due to PCT may possibly increase cutaneous
> > sclerosis in PSS. A diagnosis of PCT should be considered for patients
> > presenting scleroderma, since it is difficult to distinguish
> > sclerodermoid changes from true scleroderma.
>
> > PMID: 7616663 [PubMed - indexed for MEDLINE]
> > Who loves ya.
> > Tom
>
> > Jesus Was A Vegetarian!http://tinyurl.com/2r2nkh
>
> > Man Is A Herbivore!http://tinyurl.com/a3cc3
>
> > DEAD PEOPLE WALKINGhttp://tinyurl.com/zk9fk- Hide quoted text -
>
> - Show quoted text -

From: ironjustice on
On Jun 24, 7:43 pm, ironjustice <teamtan...(a)hotmail.com>
wrote:Plaquenil <<

Anyone care to venture a guess why phlebotomy / bloodletting isn't
used in lupus or arthritis when a drug that is an "alternative to
bloodletting" .. IS .. readily prescribed .. ?

Plaquenil - Plaquenil Side Effects - Plaquenil
Information ...Hydroxychloroquine has been beneficial for a high
percentage of patients with rheumatoid arthritis and lupus
erythematosus, especially chronic discoid lupus ...


---------------------------------------------------------------------------­------
<<snip>>
hydroxychloroquine should be the preferred alternative to phlebotomy
<<snip>>

A comparative trial of desferrioxamine and hydroxychloroquine for
treatment of porphyria cutanea tarda in alcoholic patients.
Photodermatol. 1984 Dec;1(6):286-92. Links
Marchesi L, Di Padova C, Cainelli T, Reseghetti A, Di Padova F,
Rovagnati P, Cantoni L.
Forty male alcoholic patients with porphyria cutanea tarda (PCT) were
randomly assigned to 2 groups of 20.
The 1st group received desferrioxamine (30 mg/kg body weight/day
for 1 week every 3 months) whereas the latter was given
hydroxychloroquine (200 mg twice/wk orally).
Alcohol abstinence was advised for all patients.
Improvement of cutaneous signs was evident after 6 months in
hydroxychloroquine- treated subjects and after 12 months in
desferrioxamine-treated subjects.
At the end of the 1-year clinical trial, significant decreases of
serum iron
and ferritin were found in all patients, irrespective of the therapy.
Urinary total porphyrins were reduced significantly in both groups,
but the drop was significantly more evident in hydroxychloroquine-
than
in desferrioxamine-treated subjects.
After 1 year of therapy, 4 desferrioxamine-treated patients
vs 16 hydroxychloroquine-treated subjects acquired a normal urinary
porphyrin pattern.
These results indicate that hydroxychloroquine is
more effective than desferrioxamine in inducing clinical and
biochemical remission of PCT.
Accordingly, hydroxychloroquine should be the preferred alternative
to phlebotomy, if the latter is contraindicated.


PMID: 6398430 [PubMed - indexed for MEDLINE]
--------------------------------------------------------------------------



Who loves ya.
Tom


Jesus Was A Vegetarian!
http://tinyurl.com/2r2nkh


Man Is A Herbivore!
http://tinyurl.com/4rq595


DEAD PEOPLE WALKING
http://tinyurl.com/zk9fk

> On Jun 19, 8:48 pm, "ironjust...(a)aol.com" <ironjust...(a)aol.com>
> wrote:porphyria cutanea tarda <<
>
> I suppose it is mere coincidence the drug used to treat porphyria
> cutanea tarda is very useful in lupus?
> No iron overload in lupus like in porphyria cutanea tarda?
>
> "Cutaneous symptoms disappeared"
>
> Arch Dermatol. 1980 Oct;116(10):1147-50.Links
> Hydroxychloroquine treatment of porphyria cutanea tarda.
> Malkinson FD, Levitt L.
> Six patients with skin changes and urinary porphyrin excretion
> patterns characteristic for porphyria cutanea tarda were treated with
> hydroxychloroquine sulfate therapy.
> During treatment periods ranging from five to 13 months, cutaneous
> symptoms disappeared and urinary porphyrin excretion abnormalities
> were completely or almost completely reversed.
> In three subjects, hydroxychloroquine therapy was accompanied by
> changes in the urinary excretion of iron.
> The first four patients, followed up for nine to 24 months after
> treatment, all had relapse, and substantial porphyrinuria developed
> once more; cutaneous symptoms recurred in two of these.
> Three of the four patients were re-treated, and their conditions again
> improved or went into remission with hydroxychloroquine therapy.
> In two patients, treatment responses were slower than those initially
> seen, despite the use of higher drug doses; in the third patient, the
> response to re-treatment was more rapid than that seen during the
> first treatment course.
>
> PMID: 7425660 [PubMed - indexed for MEDLINE]
> ---------------------------------------
>
> http://www.aafp.org/afp/980600ap/petri.html
>
> Treatment of Polyarthritis in Patients with Systemic Lupus
> Erythematosus
>
> Drug Comment
> NSAIDs Avoid gastrotoxic NSAIDs; counter with cytoprotective therapy
> Antimalarials Hydroxychloroquine (Plaquenil) is the antimalarial drug
> used most often in the United States; ophthalmologic monitoring is
> recommended every six to 12 months
> Glucocorticoids Individual joints may benefit from intra-articular
> injection of triamcinolone (Aristospan); severe polyarthritis flare-
> ups may be treated with intravenous "pulse therapy" consisting of
> 1,000 mg of methylprednisolone (Solumedrol) daily for three days; use
> of prednisone for maintenance therapy should be limited to 10 mg or
> less daily
> Immunosuppressive
> drugs Methotrexate (Rheumatrex) or azathioprine (Imuran) can be used
> as steroid-sparing drugs; methotrexate cannot be used during
> pregnancy
>
> ---------------------------------------------------------------------------­-----
> NSAIDs=nonsteroidal anti-inflammatory drugs.
>
> Antimalarial agents, especially hydroxychloroquine (Plaquenil), are
> frequently used in the treatment of polyarthritis. Hydroxychloroquine
> is very safe; only 1 percent of patients using it develop retinopathy.
> Retinopathy as a result of hydroxychloroquine use is usually
> reversible when the drug is discontinued.
>
> Who loves ya.
> Tom
>
> Jesus Was A Vegetarian!http://tinyurl.com/2r2nkh
>
> Man Is A Herbivore!http://tinyurl.com/4rq595
>
> DEAD PEOPLE WALKINGhttp://tinyurl.com/zk9fk
>
>
>
> > On Jun 17, 11:00 pm, ironjustice <teamtan...(a)hotmail.com>
> > wrote:Porphyria cutanea tarda <<
>
> > Just in case anyone is unaware .. porphyria cutanea tarda is iron
> > overload.
>
> > On Jun 17, 11:00 pm, ironjustice <teamtan...(a)hotmail.com> wrote:
> > Elevated uroporphyrin due to PCT <<
>
> > We also just learned throught the mistaken feeding of fish to mice
> > that meat causes elevated uroporphyrin.
> > We also just learned that when the iron is too high the vitamin C in
> > the body cannot stop the body from having elevated uroporphyrin.
>
> > Sooo .. is it the iron overload / porphyria cutanea tarda which is
> > causing the increased scleroderma in lupus .. ?
>
> > Does porphyria cutanea tarda .. share .. many .. ? ..common
> > symptoms .. ?
>
> > We know there is a VERY high rate of anemia .. in lupus.
>
> > Which we pretty much have established seems to be kinda .. strange ..
> > due to the fact .. EVERYONE with 'similar' diseases are in FACT ..
> > all .. iron OVERLOADED.
>
> > Sooo ..if one were to disregard this hyperferritinemia in lupus AS..
> > not to be recognized .. but just the OPPOSITE and USE this iron
> > overload marker AS an iron overload marker .. and what are you left
> > with .. ?
>
> > EVERY marker now points to iron overload as a LARGE problem in lupus
> > as opposed to .. "they are all iron deficient" ..
>
> > Just the OPPOSITE of what .. 'they'.. TELL you ..
>
> > Scary .. but seems to be true .. by using .. logic.
>
> > Hyperferritinemia used as a marker shows iron overload in almost all
> > SLE patients.
>
> > The rest .. ?
>
> > Seeing the marker they DO use for hyperferritinemia is SOOOOOO ..
> > high .. then we can pretty much be sure all the rest are over the low
> > marker ..
>
> > Logical .. ?
>
> > Yep ..
> > Who loves ya.
> > Tom
>
> > Jesus Was A Vegetarian!http://tinyurl.com/2r2nkh
>
> > Man Is A Herbivore!http://tinyurl.com/a3cc3
>
> > DEAD PEOPLE WALKINGhttp://tinyurl.com/zk9fk
>
> > > "Porphyria cutanea tarda should be considered for scleroderma"
>
> > > Nippon Rinsho. 1995 Jun;53(6):1463-7.Links
> > > [Scleroderma and porphyria cutanea tarda][Article in Japanese]
>
> > > Tsukazaki N, Okada S, Yoshida H.
> > > Department of Dermatology, Nagasaki University School of Medicine.
>
> > > Examination was made of sclerodermoid changes in porphyria cutanea
> > > tarda (PCT) and PCT in association with true scleroderma. Although
> > > sclerodermoid change in PCT is rare in Japan, it is important in the
> > > diagnosis of PCT when there are few other clinical signs
> > > characteristic of PCT. In the present case, slight improvement in
> > > cutaneous sclerosis was noted following treatment for PCT, but
> > > pulmonary changes somewhat intensified. The reason for the association
> > > of PCT with progressive systemic sclerosis (PSS) remains obscure.
> > > Elevated uroporphyrin due to PCT may possibly increase cutaneous
> > > sclerosis in PSS. A diagnosis of PCT should be considered for patients
> > > presenting scleroderma, since it is difficult to distinguish
> > > sclerodermoid changes from true scleroderma.
>
> > > PMID: 7616663 [PubMed - indexed for MEDLINE]
> > > Who loves ya.
> > > Tom
>
> > > Jesus Was A Vegetarian!http://tinyurl.com/2r2nkh
>
> > > Man Is A Herbivore!http://tinyurl.com/a3cc3
>
> > > DEAD PEOPLE WALKINGhttp://tinyurl.com/zk9fk-Hide quoted text -
>
> > - Show quoted text -- Hide quoted text -
>
> - Show quoted text -

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