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From: jesselev on 25 Aug 2007 12:08
On Jul 7, 4:42 am, "JOHN" <j...(a)btinternet.com> wrote:
> you would also be sleeping over a heating coil, not a good idea, like a
> sleeping blanket
>
> "jay" <jaym1...(a)hotmail.com> wrote in message
>
> news:1182382092.205894.217930(a)q69g2000hsb.googlegroups.com...
>
>
>
> > Has anyone suspected a link between long-termwaterbeduse and
> > autoimmune diseases or foodallergies? I have slept on awaterbedfor
> > approx 15 years (not continously :) and have had foodallergiesfor
> > the past 7.
>
> >Waterbedmattresses tend to contain high amounts of Phthalates (esp
> > DEHP). It is an additive that makes plastics (mostly PVC) softer and
> > more flexible. It is also found at home (vinyl flooring, wall
> > covering, shower curtains, plastic containers, paints, glues, carpet
> > backing, cabling), apparel (boots, gloves), cosmetics, musk scents,
> > car interiors, hospitals (tubing, blood bags), household/workplace
> > air/dust, etc.
>
> > DEHP falls under the category of Endocrine Disruptors or xeno-
> > estrogens. DEHP causes Lupus in genetically suseptible mice. Endocrine
> > Disruptors can cause autoimmunity. See related article below:
>
> > Spotlight on the role of hormonal factors in the emergence of
> > autoreactive B-lymphocytes.
>
> > Pathogenic autoimmunity requires a combination of inherited and
> > acquired factors. In as much as hormones influence the sexual
> > dimorphism of the immune system, it is possible that they can initiate
> > or accelerate an autoimmune process, and contribute to gender-biased
> > autoimmune disorders. Not only natural hormones, but also endocrine
> > disruptors, such as environmental estrogens, may act in conjunction
> > with other factors to override immune tolerance to self-antigens. In
> > lupus, murine and human studies demonstrate that female sex hormones
> > are implicated in disease pathogenesis. In the B cell compartment,
> > both prolactin and estrogen are immunomodulators that affect
> > maturation, selection and antibody secretion. Their impact may be
> > based on their capacity to allow autoreactive B cells to escape the
> > normal mechanisms of tolerance and to accumulate in sufficient numbers
> > to cause clinically apparent disease. Both hormones lead to the
> > survival and activation of autoreactive B cells, but they skew B cell
> > maturation towards different directions, with prolactin inducing T
> > cell-dependent autoreactive follicular B cells and estrogen eliciting
> > T cell-independent autoreactive marginal zone B cells. Differential
> > modulation of the cytokine milieu by hormones may also affect the
> > development and activation of specific mature B cell subsets. This
> > novel insight suggests that targeted manipulation of these pathways
> > may represent a promising avenue in the treatment of lupus and other
> > gender-biased autoimmune diseases.
> > PMID: 16061292
>
> > Autoreactive responses to environmental factors: 3. Mouse strain-
> > specific differences in induction and regulation of anti-DNA antibody
> > responses due to phthalate-isomers.Lim SY, Ghosh SK.
> > Department of Life sciences, Indiana State University, 403-25 N, 6th
> > St, Terre Haute, IN 47809, USA.
>
> > Little is known of the role of specific environmental factors in
> > promoting autoimmune disorders such as systemic lupus erythematosus
> > (SLE). This study addresses how exposure to phthalates, common
> > environmental factors in foods, and biomedical devices could affect
> > the immune functions of resistant and autoimmune-prone mice. We have
> > previously shown that immunization with ortho-phthalate evokes anti-
> > DNA antibody in BALB/c and NZB/W F1 mice, but only the latter suffer
> > from nephritis and high mortality. BALB/c mice, in contrast, develop
> > idiotype-specific CD8+ suppressor T cells downregulating autoreactive
> > B cells. Here we report that all phthalate-isomers (ortho-, meta- and
> > para-) are capable of inducing anti-DNA antibody responses and SLE-
> > like syndromes. Kidney pathology worsens in NZB/W F1 and to a degree,
> > in C57BL/6 mice after repeated exposure to phthalates. Only BALB/c and
> > DBA/2 overcome adverse autoreactivity by induction of Ts cells; but in
> > vivo depletion of these T cells renders these strains susceptible to
> > autoreactivity. Anti-DNA antibodies in affected NZB/W F1 are largely
> > IgG2a-type, while in BALB/c, DBA/2, and C57BL/6 mice IgG1-type. This
> > is further corroborated by cytokine analyses that imply corresponding
> > Th1/Th2 involvement. In summary, the commonly used phthalates appear
> > harmful to susceptible strains, while BALB/c and DBA/2 are spared due
> > to induction of Ts cells.
> > PMID: 15993037
>
> > Endocrine disruption in adolescence: immunologic, hematologic, and
> > bone effects in monkeys.
>
> > Environmental contaminants with estrogenic properties have the
> > potential to alter pubertal development. In addition to the
> > reproductive system, other systems that mature under the influence of
> > estrogen could be affected. This study examined the effect on immune,
> > hematologic, and bone mass parameters of treatment with estrogenic
> > agents (methoxychlor, MXC, 25 and 50 mg/kg/day; diethylstilbestrol,
> > DES, 0.5 mg/kg/day) given in the peripubertal period to female rhesus
> > monkeys. DES had striking effects on several parameters assessed
> > measures CBC and clinical chemistry including hematocrit, hemoglobin,
> > serum albumin, liver transaminases, and lipids. Circulating
> > lymphocytes, particularly B cells, were depressed by DES, and a
> > maturational shift in a memory T-cell population was altered. Bone
> > mass and length, as measured after a 9-month recovery period, were
> > significantly lower in the DES group and bone mass tended to be
> > reduced in the femur of the MXC50 group relative to controls. In
> > conclusion, the data indicate that DES had a clear effect on
> > immunohematology and bone growth, while MXC influenced fewer
> > parameters. Disruption in these systems during puberty could alter
> > adolescent risk for anemia and infectious disease and subsequent adult
> > risk for diseases such as osteoporosis, heart disease, and autoimmune
> > disease.
> > PMID: 15456917
>
> > Article about Phthalates:
> >http://www.ourstolenfuture.org/NEWSCIENCE/oncompounds/phthalates/phth...- Hide quoted text -
>
> - Show quoted text -

I just wanted to let people know what happens if you don't use
waterbed conditioner with a waterbed:

There is an excellent chance you'd eventually get sick with severe
sneezing fits, runny nose, itchy eyes, etc.. once any mold starts
developing in the waterbed mattress (and it will, believe me). You
wouldn't necessarily even notice any odor!! I hadn't! I had been
sick with sneezing fits plus... for over a year having bad night's
sleep and going thru boxes of Sudafed and it got so bad this summer, I
finally noticed my allergies were worst shortly after I'd lay down in
my waterbed! I was getting most sick within five minutes!

I called an Off-Track Bedding store and they confirmed this with me
that mold develops and causes health problems. They also said drain
the mattress, refill it and it "might" help resolve the matter. They
also told me to look for black spots inside the mattress with a strong
light while looking thru the fill plug. I certainly saw a crapload of
black spots when I looked inside mine!

I've seen nothing posted on the Internet concerning allergic reactions
(severe sneezing fits, runny nose and itchy eyes, etc..) from waterbed
(mold) as a result of not using waterbed conditioner! I hope this
information may help some people who have suffered allergies and
suspected a relation to their waterbed! I feel like having the mold
tested for $50 (a microbiologist) to see if it's toxic mold which can
be dangerous by what I've heard! I'm just going to buy a new
mattress. I'm not messing around taking chances with this stuff now
that I know it's a mold problem!

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