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From: Larry on 11 Aug 2008 18:33
On Aug 10, 2:43 pm, Tiger_Lily <m...(a)privacy.net> wrote:
> Larry wrote:
> > On Aug 10, 9:36 am, Tiger_Lily <m...(a)privacy.net> wrote:
> >> Larry wrote:
> >>> On Aug 9, 3:02 pm, Tiger_Lily <m...(a)privacy.net> wrote:
> >>>> Larry wrote:
> >>>>> On Aug 8, 3:21 pm, Alan S <loralgtweightandca...(a)gmail.com> wrote:
> >>>>>> On Thu, 7 Aug 2008 21:34:51 -0700 (PDT), Larry
> >>>>>> <boelk...(a)aol.com> wrote:
> >>>>>>> On Aug 6, 2:19 pm, Susan <neverm...(a)nomail.com> wrote:
> >>>>>>>> x-no-archive: yes
> >>>>>>>> Larry wrote:
> >>>>>>>>> Thank you Susan for your input. Yes I do remember your comments about
> >>>>>>>>> Statins. Right now I am wondering about electroyte imbalance which
> >>>>>>>>> metformin may cause. Particulary high potassium levels that it may
> >>>>>>>>> cause. As you may know electrolyte imbalance can cause heart block in
> >>>>>>>>> some patients of which I am coping with at the moment.
> >>>>>>>> I think you need to have endocrine evaluation, and a standing renin and
> >>>>>>>> aldosterone test (stand upright for 30 minutes prior to and during blood
> >>>>>>>> draw) and other adrenal hormones.
> >>>>>>>> In addition, if you're having problems with electrolyte balance, perhaps
> >>>>>>>> you need to stop the metformin for a while and see if things improve.
> >>>>>>>> Also, don't ever pump your fist or allow a tight tournequet to be used
> >>>>>>>> for your serum testing; it raises the potassium results and renders them
> >>>>>>>> completely inaccurate, as will shaking of the test tube, or sitting out
> >>>>>>>> too long after draw.
> >>>>>>>> Susan
> >>>>>>> Hello Susan: Just saw my Endo. today here in San Diego. Pretty
> >>>>>>> competent young Doc I'd say. Anyway at my request GAD test was done
> >>>>>>> and results today show 14+... high and indicates LADA. I've been
> >>>>>>> diagnosed by at least 2 doc before as T2. I do believe the recent
> >>>>>>> findings particularly supported by todays GAD results. So now
> >>>>>>> metformin, actos are dc'd, amaryl tapered and more insulin ( bolus
> >>>>>>> PP ) added. Where is dear "old Al?"
> >>>>>>> Larry/T2 changed to T 1 1/2 after 6 years of IR drugs which did very
> >>>>>>> little. Misdiagnosis from the beginning.
> >>>>>> Remind me. Haven't you suspected this for a while?
> >>>>>> Good to know you can stop wondering and get on with the
> >>>>>> right treatment.
> >>>>>> Cheers, Alan, T2, Australia.
> >>>>>> --
> >>>>>> Everything in Moderation - Except Laughter.
> >>>>>> Bloghttp://loraldiabetes.blogspot.com
> >>>>>> DLife columnhttp://tinyurl.com/5v74xrhttp://loraltravel.blogspot.com(TheTajMahal)-Hide quoted text -
> >>>>>> - Show quoted text -
> >>>>> Alan: I have never been overweight, metformin never seemed to improve
> >>>>> things. C-peptide seemed to show mid range endogenous insulin so doc
> >>>>> continued to assume I was T2 and treated as such adding on Actos and
> >>>>> then Amaryl. I managed to keep my A1c in low 7s with lots of exercise
> >>>>> and pretty good dieting. Actos didn't do anything and Amaryl worked to
> >>>>> improve fbg levels for a little while. I insisted to see an Endo and
> >>>>> also insisted that a GAD be done. So you know once again how patients
> >>>>> need to take charge as best they can. Consequently I've been over
> >>>>> medicated and have a heart block which could be related. This may
> >>>>> resolve itself since most orals are being tapered or dcd at this time.
> >>>>> Thanks for asking.
> >>>>> Larry
> >>>> what was your GAD result?
> >>>> are you on insulin now that pills have been discontinued?
> >>>> --
> >>>> kate
> >>>> type 1 since 1987www.diabetic-chat.orgwww.diabetic-talk.orghttp://www.diabetes-support...quoted text -
> >>>> - Show quoted text -
> >>> Kate: I am still on Amaryl at 4mg/day but expect to drop that drug
> >>> very soon. Metformin and Actos are now dcd. ( I was just reading that
> >>> some docs think Actos/Avandia can be beneficial in preserving the
> >>> remaining little function of b-cells. I'm not sure about that). Lantus
> >>> 9 IU at bedtime has been working wonders to improve fbg levels down to
> >>> normal range for first time since diagnosed some years ago. Now I am
> >>> starting Novalog short acting before breakfast and lunch. Maybe dinner
> >>> as well but usually don't have high bg levels post dinner for some
> >>> reason. I think of insulin therapy as a needed habit ... no more
> >>> difficult than carrying a pack of cigarettes around for smokers I
> >>> guess. .if you know what I mean.
> >>> Larry
> >> interesting that you have been left on the Amaryl
>
> >> does the Dr have a reason for this, when you are on insulin?
>
> >> --
> >> kate
> >> type 1 since 1987www.diabetic-chat.orgwww.diabetic-talk.orghttp://www.diabetes-support...Hide quoted text -
>
> >> - Show quoted text -
>
> > Kate: GAD Ab was 13.5... I am just starting at low dose Novalog 1-2 IU
> > prior to meals. I am sure Amaryl will be weaned off very soon as
> > Insulin dose is increased. I guess I am getting some benefit from
> > Amaryl in the meantime even though it might be a stressor on the
> > pancreas. I agree sooner the better to get off Amaryl. Plan to check
> > with Endo in a week or so.
>
> > Larry
>
> ahhhhhhhh you have things under control
>
> excellent! (question answered)
>
> --
> kate
> type 1 since 1987www.diabetic-chat.orgwww.diabetic-talk.orghttp://www.diabetes-support.org.uk/newly%20diagnosed.html- Hide quoted text -
> 13.
> - Show quoted text -

Kate: This maybe should be a new thread... maybe not.. My GAD was
reported at 13.02 U/ml. (URUP Labs). I tried to get there definition
of U/ml since their range is 0.00-1.45 U/mL. I suspect that 13.02 is
approximately 13 dilutions where 1 dilutions is equal to 2.0. If I am
correct I still wonder why 13.02 rather than a multiple 13.0000 is
reported. My understanding is 2 is one dilution 3 is two dilution etc.
ie 1:2. 1:4, 1:8, 1:16 (the later is 4 U/mL).. ????

Larry
From: Tiger_Lily on 11 Aug 2008 18:36
Larry wrote:
> On Aug 10, 2:43 pm, Tiger_Lily <m...(a)privacy.net> wrote:
>> Larry wrote:
>>> On Aug 10, 9:36 am, Tiger_Lily <m...(a)privacy.net> wrote:
>>>> Larry wrote:
>>>>> On Aug 9, 3:02 pm, Tiger_Lily <m...(a)privacy.net> wrote:
>>>>>> Larry wrote:
>>>>>>> On Aug 8, 3:21 pm, Alan S <loralgtweightandca...(a)gmail.com> wrote:
>>>>>>>> On Thu, 7 Aug 2008 21:34:51 -0700 (PDT), Larry
>>>>>>>> <boelk...(a)aol.com> wrote:
>>>>>>>>> On Aug 6, 2:19 pm, Susan <neverm...(a)nomail.com> wrote:
>>>>>>>>>> x-no-archive: yes
>>>>>>>>>> Larry wrote:
>>>>>>>>>>> Thank you Susan for your input. Yes I do remember your comments about
>>>>>>>>>>> Statins. Right now I am wondering about electroyte imbalance which
>>>>>>>>>>> metformin may cause. Particulary high potassium levels that it may
>>>>>>>>>>> cause. As you may know electrolyte imbalance can cause heart block in
>>>>>>>>>>> some patients of which I am coping with at the moment.
>>>>>>>>>> I think you need to have endocrine evaluation, and a standing renin and
>>>>>>>>>> aldosterone test (stand upright for 30 minutes prior to and during blood
>>>>>>>>>> draw) and other adrenal hormones.
>>>>>>>>>> In addition, if you're having problems with electrolyte balance, perhaps
>>>>>>>>>> you need to stop the metformin for a while and see if things improve.
>>>>>>>>>> Also, don't ever pump your fist or allow a tight tournequet to be used
>>>>>>>>>> for your serum testing; it raises the potassium results and renders them
>>>>>>>>>> completely inaccurate, as will shaking of the test tube, or sitting out
>>>>>>>>>> too long after draw.
>>>>>>>>>> Susan
>>>>>>>>> Hello Susan: Just saw my Endo. today here in San Diego. Pretty
>>>>>>>>> competent young Doc I'd say. Anyway at my request GAD test was done
>>>>>>>>> and results today show 14+... high and indicates LADA. I've been
>>>>>>>>> diagnosed by at least 2 doc before as T2. I do believe the recent
>>>>>>>>> findings particularly supported by todays GAD results. So now
>>>>>>>>> metformin, actos are dc'd, amaryl tapered and more insulin ( bolus
>>>>>>>>> PP ) added. Where is dear "old Al?"
>>>>>>>>> Larry/T2 changed to T 1 1/2 after 6 years of IR drugs which did very
>>>>>>>>> little. Misdiagnosis from the beginning.
>>>>>>>> Remind me. Haven't you suspected this for a while?
>>>>>>>> Good to know you can stop wondering and get on with the
>>>>>>>> right treatment.
>>>>>>>> Cheers, Alan, T2, Australia.
>>>>>>>> --
>>>>>>>> Everything in Moderation - Except Laughter.
>>>>>>>> Bloghttp://loraldiabetes.blogspot.com
>>>>>>>> DLife columnhttp://tinyurl.com/5v74xrhttp://loraltravel.blogspot.com(TheTajMahal)-Hide quoted text -
>>>>>>>> - Show quoted text -
>>>>>>> Alan: I have never been overweight, metformin never seemed to improve
>>>>>>> things. C-peptide seemed to show mid range endogenous insulin so doc
>>>>>>> continued to assume I was T2 and treated as such adding on Actos and
>>>>>>> then Amaryl. I managed to keep my A1c in low 7s with lots of exercise
>>>>>>> and pretty good dieting. Actos didn't do anything and Amaryl worked to
>>>>>>> improve fbg levels for a little while. I insisted to see an Endo and
>>>>>>> also insisted that a GAD be done. So you know once again how patients
>>>>>>> need to take charge as best they can. Consequently I've been over
>>>>>>> medicated and have a heart block which could be related. This may
>>>>>>> resolve itself since most orals are being tapered or dcd at this time.
>>>>>>> Thanks for asking.
>>>>>>> Larry
>>>>>> what was your GAD result?
>>>>>> are you on insulin now that pills have been discontinued?
>>>>>> --
>>>>>> kate
>>>>>> type 1 since 1987www.diabetic-chat.orgwww.diabetic-talk.orghttp://www.diabetes-support...quoted text -
>>>>>> - Show quoted text -
>>>>> Kate: I am still on Amaryl at 4mg/day but expect to drop that drug
>>>>> very soon. Metformin and Actos are now dcd. ( I was just reading that
>>>>> some docs think Actos/Avandia can be beneficial in preserving the
>>>>> remaining little function of b-cells. I'm not sure about that). Lantus
>>>>> 9 IU at bedtime has been working wonders to improve fbg levels down to
>>>>> normal range for first time since diagnosed some years ago. Now I am
>>>>> starting Novalog short acting before breakfast and lunch. Maybe dinner
>>>>> as well but usually don't have high bg levels post dinner for some
>>>>> reason. I think of insulin therapy as a needed habit ... no more
>>>>> difficult than carrying a pack of cigarettes around for smokers I
>>>>> guess. .if you know what I mean.
>>>>> Larry
>>>> interesting that you have been left on the Amaryl
>>>> does the Dr have a reason for this, when you are on insulin?
>>>> --
>>>> kate
>>>> type 1 since 1987www.diabetic-chat.orgwww.diabetic-talk.orghttp://www.diabetes-support...Hide quoted text -
>>>> - Show quoted text -
>>> Kate: GAD Ab was 13.5... I am just starting at low dose Novalog 1-2 IU
>>> prior to meals. I am sure Amaryl will be weaned off very soon as
>>> Insulin dose is increased. I guess I am getting some benefit from
>>> Amaryl in the meantime even though it might be a stressor on the
>>> pancreas. I agree sooner the better to get off Amaryl. Plan to check
>>> with Endo in a week or so.
>>> Larry
>> ahhhhhhhh you have things under control
>>
>> excellent! (question answered)
>>
>> --
>> kate
>> type 1 since 1987www.diabetic-chat.orgwww.diabetic-talk.orghttp://www.diabetes-support.org.uk/newly%20diagnosed.html- Hide quoted text -
>> 13.
>> - Show quoted text -
>
> Kate: This maybe should be a new thread... maybe not.. My GAD was
> reported at 13.02 U/ml. (URUP Labs). I tried to get there definition
> of U/ml since their range is 0.00-1.45 U/mL. I suspect that 13.02 is
> approximately 13 dilutions where 1 dilutions is equal to 2.0. If I am
> correct I still wonder why 13.02 rather than a multiple 13.0000 is
> reported. My understanding is 2 is one dilution 3 is two dilution etc.
> ie 1:2. 1:4, 1:8, 1:16 (the later is 4 U/mL).. ????
>
> Larry
tee hee

well, i 'got' the part where your GAD is 13.02 and NORMAL is 0.0 to 1.45 :)

they didn't have GAD or c-peptide when i was diagnosed type 1, they went
on the ketones i had and the extremely quick weight loss (from 135 to 87
lbs in 3 weeks)

--
kate
type 1 since 1987
www.diabetic-chat.org
www.diabetic-talk.org
http://www.diabetes-support.org.uk/newly%20diagnosed.html
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