Phlebotomy Prevents Thrombosis
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From: Pope Pie (Sy Lehrman) on 7 Jul 2008 15:35 ironjustice wrote: > On Jul 7, 11:23 am, ironjustice <ironjust...(a)aol.com> wrote: > thrombosis101 << > >> What is deep vein thrombosis? >> >> In deep vein thrombosis a blood clot forms in one of the veins deep >> inside the leg. It can occur at any age but is much more common in >> older people. It can be caused by a wide variety of factors other than >> air travel. The clot may break away from its position and travel >> through the heart to the lung where it may cause severe symptoms which >> can result in death. >> Speaking as someone who has experienced both DVT and pulmonary embolism resulting there from I would like to point out that if somebody came to me in the ER proposing that blood letting was the cure for what ailed me I would get out of there quite quickly and find a way to get to a real doctor. It is entirely reasonable that if you bleed someone enough the DVT will trouble them no longer, but the same could be said of taking large quantities of barbiturates and it would probably be more pleasant, take enough and the DVT will no longer be a problem. Bur, please, feel free to rave on about this nonsense. Could be someone will read it. Now, if you will excuse me I have a new mailer, thunderbired, and haven't quite figured out where the bozo file is. Bye......
From: ironjustice on 7 Jul 2008 22:02 On Jul 7, 11:47 am, "Paul T. Holland" <pholl...(a)bellatlantic.net> wrote:long winded whack << "The venesection group resulted in much better recovery" Zhonghua Shen Jing Jing Shen Ke Za Zhi. 1990 Apr;23(2):84-6, 126.Links [Hemodilution in the treatment of acute cerebral thrombosis][Article in Chinese] Luo H. P.L.A 202th Hospital, ShenYang. 11 cases of acute cerebral thrombosis were treated with a combination of venesection (400-800 ml of blood being let out at a time) and administration of an equal volume of low-molecular weight dextran solution Thereafter 500 ml of the dextran solution was given to each patient every day for 15 days. A comparison was made between this group and another group of patients who received just dextran. In the venesection group the mean value of hemoglobin was reduced from 15 g% to 13 g%, that of hematocrit from 44.6% to 40%, and that of the whole blood viscosity from 5.15 to 4.40. The neurological scores showed marked changes after three days of venesection. On the 21st day the scores in the venesection group increased by 31.6% (20.1 points) and that in the control group increased by 12.6% (7.7 points). Evidently the venesection group resulted in much better recovery (P less than 0.001). PMID: 1697233 Who loves ya. Tom Jesus Was A Vegetarian! http://tinyurl.com/2r2nkh Man Is A Herbivore! http://tinyurl.com/4rq595 DEAD PEOPLE WALKING http://tinyurl.com/zk9fk
From: ironjustice on 8 Jul 2008 00:09 On Jul 7, 12:27 pm, ironjustice <teamtan...(a)hotmail.com> wrote: thrombosis101 << "Iron deposits in atherosclerotic lesions" Circulation. 1999 Mar 9;99(9):1222-9. Links Iron-deficient diet reduces atherosclerotic lesions in apoE-deficient mice. Lee TS, Shiao MS, Pan CC, Chau LY. Division of Cardiovascular Research, Institute of Biomedical Sciences, Academia Sinica Laboratory, Taipei, Taiwan. BACKGROUND: Iron deposition is evident in human atherosclerotic lesions, suggesting that iron may play a role in the development of atherosclerosis. To test this idea, the correlation between the extent of iron deposition and the severity of atherosclerosis in apolipoprotein E (apoE)-deficient mice was investigated. Furthermore, the effect of a low-iron diet on the progression of atherosclerotic lesions in these animals was evaluated. METHODS AND RESULTS: Iron deposition in tissues of apoE-deficient mice was examined by Perls' staining method. The results clearly demonstrated that iron deposits are present in atherosclerotic lesions and tissue sections of heart and liver in an age-dependent manner. When the young mice received a low-iron diet for 3 months, the hematocrit, serum iron, hemoglobin, and cholesterol concentrations were not significantly altered compared with those of littermates placed on a chow diet. However, the serum ferritin level of animals in the iron-restricted group was 27% to 30% lower than that of the control group in either sex. Furthermore, the lipoproteins isolated from the iron-restricted group exhibited greater resistance to copper-induced oxidation. Histological examination revealed that atherosclerotic lesions developed in mice fed a low-iron diet were significantly smaller than those found in control littermates. Likewise, the iron deposition as well as tissue iron content was much less in aortic tissues of the iron-restricted animals. Circulating autoantibodies to oxidized LDL and immunostains for epitopes of malondialdehyde-modified LDL detected on lesions were also significantly lower in mice fed a low-iron diet. CONCLUSIONS: Iron deposition is closely associated with the progression of atherosclerosis in apoE-deficient mice. Restriction in dietary iron intake leads to significant inhibition of lesion formation in these animals. These results suggest that the beneficial effect of a low-iron diet may be mediated, at least in part, by the reduction of iron deposition as well as LDL oxidation in vascular lesions. PMID: 10069791 ----------------------------- J Biomed Sci. 2003 Sep-Oct;10(5):510-7.Links Dietary iron restriction increases plaque stability in apolipoprotein- e-deficient mice. Lee HT, Chiu LL, Lee TS, Tsai HL, Chau LY. Institute of Biomedical Sciences, Academia Sinica, Taipei, Taiwan, ROC. Accumulative evidence has supported the role of iron in the development of atherosclerosis. To test whether iron-mediated oxidative stress influences plaque stability, apoliporotein-E (ApoE)-deficient mice (3 months old) were placed on a chow diet or a low-iron diet for 3 months, and the abundance of interstitial collagen and the expression of the matrix degradation-associated enzyme, matrix metalloproteinase-9 (MMP-9), in vascular lesions were assessed. A low-iron diet appeared to reduce iron deposition while substantially increasing collagen content of lesions in mice. Immunostaining demonstrated lower expression of MMP-9 in lesions of iron-restricted animals. Likewise, SDS-PAGE zymography revealed lower gelatinolytic activities in aortic tissues and sera of the same group of animals. When older ApoE-deficient mice (5 months old) received a low-iron diet for 2 months, development of the lesion area was not significantly affected. However, the lesional collagen content was much higher in the iron- restricted group of animals, and MMP-9 expression in aortic tissues from the same group of mice was significantly lower. Treatment of murine J774 macrophages with increasing concentrations of ferric ammonium citrate significantly enhanced the amount of MMP-9 secreted. Together, these data indicate that decreased vascular iron content following dietary iron restriction in ApoE-deficient mice leads to lower matrix degradation capacity and increased plaque stability. Copyright 2003 National Science Council, ROC and S. Karger AG, Basel PMID: 12928591 Who loves ya. Tom Jesus Was A Vegetarian! http://tinyurl.com/2r2nkh Man Is A Herbivore! http://tinyurl.com/4rq595 DEAD PEOPLE WALKING http://tinyurl.com/zk9fk > On Jul 7, 11:23 am, ironjustice <ironjust...(a)aol.com> wrote: > thrombosis101 << > > "Evidently the venesection group resulted in much better recovery" > > [Hemodilution in the treatment of acute cerebral thrombosis] > Zhonghua Shen Jing Jing Shen Ke Za Zhi. > 1990 Apr;23(2):84-6, 126.Links > > Luo H. > P.L.A 202th Hospital, ShenYang. > > 11 cases of acute cerebral thrombosis were treated with a combination > of venesection (400-800 ml of blood being let out at a time) and > administration of an equal volume of low-molecular weight dextran > solution > Thereafter 500 ml of the dextran solution was given to each patient > every day for 15 days. > A comparison was made between this group and another group of patients > who received just dextran. > In the venesection group the mean value of hemoglobin was reduced from > 15 g% to 13 g%, that of hematocrit from 44.6% to 40%, and that of the > whole blood viscosity from 5.15 to 4.40. > The neurological scores showed marked changes after three days of > venesection. On the 21st day the scores in the venesection group > increased by 31.6% (20.1 points) and that in the control group > increased by 12.6% (7.7 points). > Evidently the venesection group resulted in much better recovery (P > less than 0.001). > > PMID: 1697233 > > Who loves ya. > Tom > > Jesus Was A Vegetarian!http://tinyurl.com/2r2nkh > > Man Is A Herbivore!http://tinyurl.com/4rq595 > > DEAD PEOPLE WALKINGhttp://tinyurl.com/zk9fk > > > > > On Jul 7, 11:13 am, ironjustice <ironjust...(a)aol.com> wrote: > > > wrote: thrombosis101 << > > > "Up to one third of the population have some degree of thrombophelia" > > > Deep Vein Thrombosis in Air Travellers > > by Maurice McKeown, BDS, PhD > > > The problem of deep vein thrombosis (DVT) after airline travel rises > > to public consciousness from time to time as the popular press report > > stories about healthy young travellers succumbing to the condition, or > > provide details of high profile cases going to court. > > > What is deep vein thrombosis? > > > In deep vein thrombosis a blood clot forms in one of the veins deep > > inside the leg. It can occur at any age but is much more common in > > older people. It can be caused by a wide variety of factors other than > > air travel. The clot may break away from its position and travel > > through the heart to the lung where it may cause severe symptoms which > > can result in death. > > > Who loves ya. > > Tom > > > Jesus Was A Vegetarian!http://tinyurl.com/2r2nkh > > > Man Is A Herbivore!http://tinyurl.com/4rq595 > > > DEAD PEOPLE WALKINGhttp://tinyurl.com/zk9fk > > > > Stay OFF my threads. > > > >http://www.bioscience.org/1999/v4/e/hillbom/fulltext.htm > > > > 1. ABSTRACT > > > > Free radicals are involved in the formation of both atherosclerosis > > > and thrombosis. Therefore, considerable interest has recently been > > > aroused by their role in the development of ischemic cerebral injury. > > > Experimental observations suggest that antioxidants could reduce > > > cerebral arterial vasospasm, reduce infarct size and prevent the > > > development of both atherosclerosis and thrombosis. > > > > Who loves ya. > > > Tom > > > > Jesus Was A Vegetarian!http://tinyurl.com/2r2nkh > > > > Man Is A Herbivore!http://tinyurl.com/4rq595 > > > > DEAD PEOPLE WALKINGhttp://tinyurl.com/zk9fk-Hide quoted text - > > > - Show quoted text -- Hide quoted text - > > - Show quoted text -
From: ironjustice on 8 Jul 2008 08:36 On Jul 7, 12:35 pm, "Pope Pie (Sy Lehrman)" <lao...(a)spam.cox.net> wrote: if somebody came to me in the ER proposing that blood letting was the cure for what ailed me I would get out of there quite quickly and find a way to get to a real doctor. << Radiactive phosphorus .. ? Who loves ya. Tom Jesus Was A Vegetarian! http://tinyurl.com/2r2nkh Man Is A Herbivore! http://tinyurl.com/4rq595 DEAD PEOPLE WALKING http://tinyurl.com/zk9fk > ironjustice wrote: > > On Jul 7, 11:23 am, ironjustice <ironjust...(a)aol.com> wrote: > > thrombosis101 << > > >> What is deep vein thrombosis? > > >> In deep vein thrombosis a blood clot forms in one of the veins deep > >> inside the leg. It can occur at any age but is much more common in > >> older people. It can be caused by a wide variety of factors other than > >> air travel. The clot may break away from its position and travel > >> through the heart to the lung where it may cause severe symptoms which > >> can result in death. > > Speaking as someone who has experienced both DVT and pulmonary embolism > resulting there from I would like to point out that if somebody came to > me in the ER proposing that blood letting was the cure for what ailed me > I would get out of there quite quickly and find a way to get to a real > doctor. > > It is entirely reasonable that if you bleed someone enough the DVT will > trouble them no longer, but the same could be said of taking large > quantities of barbiturates and it would probably be more pleasant, take > enough and the DVT will no longer be a problem. > > Bur, please, feel free to rave on about this nonsense. Could be someone > will read it. Now, if you will excuse me I have a new mailer, > thunderbired, and haven't quite figured out where the bozo file is. > Bye......
From: ironjustice on 8 Jul 2008 08:51
On Jul 7, 12:27 pm, ironjustice <teamtan...(a)hotmail.com> wrote: thrombosis101 << "The treatment is aimed at reducing the blood counts" "The usual initial treatment for most patients is phlebotomy." http://www.accessmedicine.com/content.aspx?aID=2144261 Excerpt: "The treatment of patients in the plethoric phase of the disease is aimed at ameliorating symptoms and decreasing the risk of thrombosis or bleeding by reducing the blood counts. The red count and hematocrit can be controlled in some patients by periodic phlebotomy, but administration of drugs that suppress marrow activity also is required to control the platelet and white counts. Both treatment modalities are used in most patients. Table 56-4 summarizes the advantages and disadvantages of various forms of therapy. The usual initial treatment for most patients is phlebotomy.50,238 The rationale for phlebotomy therapy of polycythemia vera is based on a widely quoted paper that suggested that the risk of thrombosis in polycythemia vera was proportional to the elevation in hematocrit.239 The underlying mechanisms causing thrombosis in polycythemia vera are not fully known, but the hematocrit likely is not the only, and may not even be the principal, risk factor. Who loves ya. Tom Jesus Was A Vegetarian! http://tinyurl.com/2r2nkh Man Is A Herbivore! http://tinyurl.com/4rq595 DEAD PEOPLE WALKING http://tinyurl.com/zk9fk > On Jul 7, 11:23 am, ironjustice <ironjust...(a)aol.com> wrote: > thrombosis101 << > > "Evidently the venesection group resulted in much better recovery" > > [Hemodilution in the treatment of acute cerebral thrombosis] > Zhonghua Shen Jing Jing Shen Ke Za Zhi. > 1990 Apr;23(2):84-6, 126.Links > > Luo H. > P.L.A 202th Hospital, ShenYang. > > 11 cases of acute cerebral thrombosis were treated with a combination > of venesection (400-800 ml of blood being let out at a time) and > administration of an equal volume of low-molecular weight dextran > solution > Thereafter 500 ml of the dextran solution was given to each patient > every day for 15 days. > A comparison was made between this group and another group of patients > who received just dextran. > In the venesection group the mean value of hemoglobin was reduced from > 15 g% to 13 g%, that of hematocrit from 44.6% to 40%, and that of the > whole blood viscosity from 5.15 to 4.40. > The neurological scores showed marked changes after three days of > venesection. On the 21st day the scores in the venesection group > increased by 31.6% (20.1 points) and that in the control group > increased by 12.6% (7.7 points). > Evidently the venesection group resulted in much better recovery (P > less than 0.001). > > PMID: 1697233 > > Who loves ya. > Tom > > Jesus Was A Vegetarian!http://tinyurl.com/2r2nkh > > Man Is A Herbivore!http://tinyurl.com/4rq595 > > DEAD PEOPLE WALKINGhttp://tinyurl.com/zk9fk > > > > > On Jul 7, 11:13 am, ironjustice <ironjust...(a)aol.com> wrote: > > > wrote: thrombosis101 << > > > "Up to one third of the population have some degree of thrombophelia" > > > Deep Vein Thrombosis in Air Travellers > > by Maurice McKeown, BDS, PhD > > > The problem of deep vein thrombosis (DVT) after airline travel rises > > to public consciousness from time to time as the popular press report > > stories about healthy young travellers succumbing to the condition, or > > provide details of high profile cases going to court. > > > What is deep vein thrombosis? > > > In deep vein thrombosis a blood clot forms in one of the veins deep > > inside the leg. It can occur at any age but is much more common in > > older people. It can be caused by a wide variety of factors other than > > air travel. The clot may break away from its position and travel > > through the heart to the lung where it may cause severe symptoms which > > can result in death. > > > Who loves ya. > > Tom > > > Jesus Was A Vegetarian!http://tinyurl.com/2r2nkh > > > Man Is A Herbivore!http://tinyurl.com/4rq595 > > > DEAD PEOPLE WALKINGhttp://tinyurl.com/zk9fk > > > > Stay OFF my threads. > > > >http://www.bioscience.org/1999/v4/e/hillbom/fulltext.htm > > > > 1. ABSTRACT > > > > Free radicals are involved in the formation of both atherosclerosis > > > and thrombosis. Therefore, considerable interest has recently been > > > aroused by their role in the development of ischemic cerebral injury. > > > Experimental observations suggest that antioxidants could reduce > > > cerebral arterial vasospasm, reduce infarct size and prevent the > > > development of both atherosclerosis and thrombosis. > > > > Who loves ya. > > > Tom > > > > Jesus Was A Vegetarian!http://tinyurl.com/2r2nkh > > > > Man Is A Herbivore!http://tinyurl.com/4rq595 > > > > DEAD PEOPLE WALKINGhttp://tinyurl.com/zk9fk-Hide quoted text - > > > - Show quoted text -- Hide quoted text - > > - Show quoted text - |