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From: starwarsmum on 23 Aug 2007 10:26
Hi,

I tried reducing my medication last week and, in addition to having
heartburn and pain, I regurgitated both liquids and solids which I
don't do when on the medication. I have read the Nexium info and can't
find any reason for this, it talks only about stopping acid
production. I know that the PPIs don't affect the LES, they just
change the refluxate, but I would notice if I was regurgitating solid
food whether it was acidic or not. Needless to say I went back on the
meds after a few days and I feel way better now, no more pain or
regurgitation.

Amy

From: Mel Smith on 26 Aug 2007 12:18
Amy said:

> I tried reducing my medication last week and, in addition to having
> heartburn and pain, I regurgitated both liquids and solids which I
> don't do when on the medication. I have read the Nexium info and can't
> find any reason for this, it talks only about stopping acid
> production. I know that the PPIs don't affect the LES, they just
> change the refluxate, but I would notice if I was regurgitating solid
> food whether it was acidic or not. Needless to say I went back on the
> meds after a few days and I feel way better now, no more pain or
> regurgitation.

Amy:

I sympathize !

I had a serious shoulder injury last Sunday while golfing. Within one
day, I began having stinging in my lower esophagus, and then throwing up.
(Would the injury stress have caused this stomach flare-up ?)

So, I stopped my daily Losec dose (its called Prilosec in the U.S.A) and
went out to WalMart and bought the 'Equate' brand of Zantac 75 (Ranitidine),
and also some Equate-style PepcidAC (Famotidine). (Months ago, I tried
Nexium and was immediately and badly constipated)

Over the last several days I've been rotating my meds thru Ranitidine,
Famotidine, and Tums, trying to stay away from Losec for awhile.

The reason I'm trying to stay away from Losec:
- Losec cuts Acid
- Acid fights bacteria in the gut.
- No Acid, more bacteria.
- Most ulcers are caused by bacteria.

(I hope Dr. Howard McC. will comment on the above -- even rip my
so-called logic apart. If he does, I'll got back on Losec again. I just
seem to be having a lesser and lesser effect using Losec. Puzzle, puzzle
....)

I am really perplexed trying to stave off what seem like a burst of
sudden ulcers, esophagal pains (stinging, aches, etc).

Any further advice is greatly appreciated.

-Mel Smith


From: Vanny on 26 Aug 2007 12:49
My guess would be that you stop your PPIs and end up with the acid reflux,
which causes inflammation in the oesophagus and perhaps in your stomach,
which causes constriction of the food pipe and hence regurgitation.

Check that you have implemented all the lifestyle changes, which help
alleviate GERD symptoms together with the meds. in most patients
http://www.gicare.com/pated/ecdgs39.htm Try stopping drinking milk for a
few days and see if that helps you too.

The lifestyle changes are allowing me to stop taking my meds altogether
successfully for the best part of a week now with no adverse effects. I just
have to keep on the straight and narrow.

I am a bit of the exception as a lot of my GERD is caused by Crohn's
inflammation and the disease seems to have subsided over the last week
leading to less intestinal inflammation and a lower differential pressure
between the stomach and the oesophagus. I am still sleeping raised and
sticking to my GERD diet because the last time I had a PPI holiday and
started to experiment with my food it didn't last for very long. I would
like to manage my illness by lifestyle alone because I am on a heavy
medication load for Crohn's with short bowel syndrome and heart failure
including chemotherapy (cytostatic - Mercaptopurine), steroids and Tincture
of Opium.

Vanny


"starwarsmum" <mum2my2boys(a)shaw.ca> schrieb im Newsbeitrag
news:1187879161.938300.280540(a)x35g2000prf.googlegroups.com...
> Hi,
>
> I tried reducing my medication last week and, in addition to having
> heartburn and pain, I regurgitated both liquids and solids which I
> don't do when on the medication. I have read the Nexium info and can't
> find any reason for this, it talks only about stopping acid
> production. I know that the PPIs don't affect the LES, they just
> change the refluxate, but I would notice if I was regurgitating solid
> food whether it was acidic or not. Needless to say I went back on the
> meds after a few days and I feel way better now, no more pain or
> regurgitation.
>
> Amy
>


From: Howard McCollister on 26 Aug 2007 12:55
In article <5jdnfdF3r647mU1(a)mid.individual.net>,
"Mel Smith" <medsyntel(a)aol.com> wrote:

>
> I had a serious shoulder injury last Sunday while golfing. Within one
> day, I began having stinging in my lower esophagus, and then throwing up.
> (Would the injury stress have caused this stomach flare-up ?)
>
> So, I stopped my daily Losec dose (its called Prilosec in the U.S.A) and
> went out to WalMart and bought the 'Equate' brand of Zantac 75 (Ranitidine),
> and also some Equate-style PepcidAC (Famotidine). (Months ago, I tried
> Nexium and was immediately and badly constipated)
>
> Over the last several days I've been rotating my meds thru Ranitidine,
> Famotidine, and Tums, trying to stay away from Losec for awhile.
>
> The reason I'm trying to stay away from Losec:
> - Losec cuts Acid
> - Acid fights bacteria in the gut.
> - No Acid, more bacteria.
> - Most ulcers are caused by bacteria.
>
> (I hope Dr. Howard McC. will comment on the above -- even rip my
> so-called logic apart. If he does, I'll got back on Losec again. I just
> seem to be having a lesser and lesser effect using Losec. Puzzle, puzzle
> ...)
>
> I am really perplexed trying to stave off what seem like a burst of
> sudden ulcers, esophagal pains (stinging, aches, etc).
>
> Any further advice is greatly appreciated.
>
> -Mel Smith

There is always bacteria in the stomach. The concern about ulcers is
related to the specific bacteria helicobacter pylori. Acid levels won't
have any significant effect on the presence, absence, or extent of that
particular bug.

I don't see any relationship between your shoulder injury and your
abdominal pain unless you began taking some kind of NSAID for the
injury. That particular group of drugs can indeed have a negative and
potentially painful effect on the lining of your stomach. It is usually
difficult to distinguish between the lower esophagus and the stomach as
the source of such abdominal pain.

HMc
From: Mel Smith on 27 Aug 2007 10:40
Dr. H McC said:

> I don't see any relationship between your shoulder injury and your
> abdominal pain unless you began taking some kind of NSAID for the
> injury. That particular group of drugs can indeed have a negative and
> potentially painful effect on the lining of your stomach. It is usually
> difficult to distinguish between the lower esophagus and the stomach as
> the source of such abdominal pain.


Dr. Howard:

I only took about a total of two Tylonol 3 tablets over the last week,
and now the stomach/esophagous stinging symptoms have slowly abated. My
stinging pain and on/off ache is loacted about two inches above my belly
button -- but this morning no aches, stings, etc. (still have some
controllable heartburn though :(( )

I'll see my own GP this afternoon for advice on physio and my stomach.

Thanks for above info.

-Mel Smith


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