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From: Marshall Price on 6 Nov 2008 21:16
news.chi.sbcglobal.net wrote:
> You beat me to it. That has been on my mind for last several days.
> Aspirin works, but it is not known how. Which brings me to my theory that
> everything is not known "how" but just is. I am referring to my ever
> conscious effect of medical stimulants transferring harm to innocent people
> known to the user of anti-depressants, marijuana, etc. in the form of
> crohns. and the harm goes wherever the victim goes, as the stimulant
> follows the mind. How? another unknown process, but just as certain as
> aspirin works, so do the anti-depressants work also, albeit not in the "good
> for aspirin does" A mystery of long standing for both medications. Any
> ideas, besides that the mode of transporting the stimulants is not akin to
> how aspirin works. But there are mysteries in both meds.
> Gail Michael
> "Marshall Price" <d021317c(a)yahoo.com> wrote in message
> news:su6dnV8F05LBgqTVnZ2dnUVZ_t_inZ2d(a)earthlink.com...
>> ironjustice wrote:
>>
>>> Med Hypotheses 1998 Mar;50(3):239-51
>>>
>>> A chelate theory for the mechanism of action of aspirin-like drugs.
>>> Wang X
>>> Department of Pathology, Cornell University Medical College, New York,
>>> NY 10021, USA. xw...(a)mail.med.cornell.edu
>>>
>>> Two hundred years after the discovery of the pharmaceutical usefulness
>>> of aspirin, it and aspirin-like drugs, a family with an
>>> ever-increasing number of members, are an indispensable part of modern
>>> life. However, the question as to how these drugs work in the body
>>> has remained unsettled. It is postulated here that this group of
>>> drugs may exert their therapeutic (and adverse) effects by chelating
>>> various physiologically important metallic cations in the body.
>>> The chelate theory is supported by the vast majority, if not all, of
>>> the observations on these drugs made in the past.
>>>
>>> PMID: 9578329, UI: 98237440
>> I'd like to read more about this hypothesis. Evidently, it's been
>> around for over a decade. Whatever became of it?
>>
>> --
>> Marshall Price of Miami
>> Known to Yahoo as d021317c
>
>
I'm as puzzled by Crohn's as everybody else is, but your "theory," that
"everything is not known 'how' but just is," seems to be an attack on
the very foundation of science. If the reasons for things were
undiscoverable, all would be lost! Progress in science would be impossible.

Someday, I'm sure, a breakthrough will occur in understanding the
pathological basis of Crohn's (and ulcerative colitis), and it will
suggest new therapeutic approaches. Meanwhile, the discovery that
certain drugs and procedures can help is of encouraging significance to
medicine. I have no doubt that more will be discovered, and we're all
eager for answers. We must look for "the hows" as well as treatments.

--
Marshall Price of Miami
Known to Yahoo as d021317c
From: ironjustice on 6 Nov 2008 21:58
On Nov 6, 6:16 pm, Marshall Price <d0213...(a)yahoo.com> wrote:
Someday, I'm sure, a breakthrough will occur in understanding the
pathological basis of Crohn's (and ulcerative colitis), and it will
suggest new therapeutic approaches.  Meanwhile, the discovery that
certain drugs and procedures can help is of encouraging significance
to
medicine.  I have no doubt that more will be discovered, and we're all
eager for answers.  We must look for "the hows" as well as treatments.
<<

This will only happen with a publicly funded system ..

Orrr .. the private citizen who keeps his eyes open ..

Drug companies are just that .

They are funded to produce profitable .. drugs.

They look and see what .. works ..

They are not interested in .. why.

They may KNOW why but that is not funded and the hypothesis needs to
be worked on and that is not what they are paid to .. do.

You can see in MANY working scientists their abilities are curtailed
by the fact they have had to work in OTHER fields of research CONTRARY
to the time they could spend ON their hypothesis ..

I showed this SPECIFICALLY in a study in which the researcher / drug
company was looking for a role of iron in multiple sclerosis and WHILE
doing this discovered .. something.

He quit his work it seemed INTO the 'iron end' and the drug was
developed.

Whether he continued in trying to find 'why' .. and had the MONEY to
wonder 'why' ..

Nobody is paying him to wonder .. why.

The only way he can further the hypothesis is by the open SHARING of
information as we seem to be doing now.

Then if HE personally doesn't have the time or money to continue in
this work then the public sharing of the information just may well ..
getter done.

HE personally may not become the 'gotoguy' but I doubt if in the big
scheme of things that wasn't what was pushing him in the first place.

Imho ..

A little detective work now can go a long way because they are ..
writing stuff down.


Who loves ya.
Tom


Jesus Was A Vegetarian!
http://tinyurl.com/2r2nkh


Man Is A Herbivore!
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http://tinyurl.com/zk9fk



>
> --
> Marshall Price of Miami
> Known to Yahoo as d021317c- Hide quoted text -
>
> - Show quoted text -

From: news.chi.sbcglobal.net on 8 Nov 2008 01:46
It is allright not always to know why a drug works as it does. Or we would
miss out many good drugs. But when a drug has deadly side effects that can
be noted by the astute, it is time to ban that drug. My theory on the
cause of crohns cannot ever be proven how it works (at least I don't think
it could). Words fail me for the moment. Crohns is a forever plague
affecting thousands. And an ordinary person cannot convince barely
anyone that it is harmful. Science simply does not apply here. Does
that mean we should let it continue what the eye cannot see.
Gail


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