From: M Dunne on
Hope this isn't too OT; but I have a friend with lupus, and was wondering if
there are any specifically *nutrition-related* insights that people
hereabouts might have.

He seems to have very badly disrupted digestion: would it be a good idea to
get him on a high-dose regimen of vitamin and mineral supplements?

All thoughts and ideas gratefully received!

John Gohd: don't bother to respond.

Thanks to everyone.

M.


From: Susan on
x-no-archive: yes

M Dunne wrote:
> Hope this isn't too OT; but I have a friend with lupus, and was wondering if
> there are any specifically *nutrition-related* insights that people
> hereabouts might have.
>
> He seems to have very badly disrupted digestion: would it be a good idea to
> get him on a high-dose regimen of vitamin and mineral supplements?
>
> All thoughts and ideas gratefully received!
>
> John Gohd: don't bother to respond.
>
> Thanks to everyone.
>
> M.
>
>

If he's having gut problems, pouring pills into him wouldn't be first on
my list. I'd try an elimination diet, first. Start with starches,
wheat first, then work on through the list. You can google up a
protocol for doing it.

Also consider whether it's truly lupus or an infectious disease causing
lupus like findings, like tick borne diseases can.

Susan
From: Don Wiss on
On Mon, 17 Apr 2006 22:03:47 GMT, "M Dunne" <MarcusDunn(a)homfework.com>
wrote:

>Hope this isn't too OT; but I have a friend with lupus, and was wondering if
>there are any specifically *nutrition-related* insights that people
>hereabouts might have.
>
>He seems to have very badly disrupted digestion: would it be a good idea to
>get him on a high-dose regimen of vitamin and mineral supplements?
>
>All thoughts and ideas gratefully received!

The foreword to _Dangerous Grains_ (forward written by Jonathan Wright,
M.D.) discusses Dr. Chris Reading's treatment of more than one hundred
patients with systemic lupus. These patients eliminated gluten and dairy
from their diets and their symptoms disappeared and their blood tests
normalized.

For the book see: http://www.amazon.com/gp/product/1583331298/

Don <www.donwiss.com> (e-mail link at home page bottom).
From: Hey Rocco on
In article <jbf842d5ijdc4c63v0olplrmgjki0qm87r(a)4ax.com>, Don Wiss
<donwiss(a)no_spam.com> wrote:

> On Mon, 17 Apr 2006 22:03:47 GMT, "M Dunne" <MarcusDunn(a)homfework.com>
> wrote:
>
> >Hope this isn't too OT; but I have a friend with lupus, and was wondering if
> >there are any specifically *nutrition-related* insights that people
> >hereabouts might have.
> >
> >He seems to have very badly disrupted digestion: would it be a good idea to
> >get him on a high-dose regimen of vitamin and mineral supplements?
> >
> >All thoughts and ideas gratefully received!
>
> The foreword to _Dangerous Grains_ (forward written by Jonathan Wright,
> M.D.) discusses Dr. Chris Reading's treatment of more than one hundred
> patients with systemic lupus. These patients eliminated gluten and dairy
> from their diets and their symptoms disappeared and their blood tests
> normalized.
>
> For the book see: http://www.amazon.com/gp/product/1583331298/
>
> Don <www.donwiss.com> (e-mail link at home page bottom).

Eliminating wheat & gluten is a good premise, but Dr Walsh is saying to
go one step further. "Get at the oxidative stress in the gut" which
could be causing it in the first place. Although he does not refer to
Lupus, it's related, so I'll paste it below... Also, if you read
between the lines, there is a zinc-carnosine supplement on the market
that should remedy the oxidative stress in the gut.
Rocco

Celiac Disease, Wheat and Dairy Sensitivity
From William Walsh, Ph.D., Senior Scientist, Pfeiffer Treatment Center
www.hriptc.org

There are classic symptoms/markers of gluten intolerance which enable
you to determine the small percentage of people that have symptoms
consistent with this disorder. Examples are (1) compulsive, ritualistic
behavior, (2) family history of malabsorption, (3) frequent, explosive
bowel movements, (4) lethargy, (5) abdominal pain, and (6) Dermatitis
Herpetiformis (skin disorder). One could screen the population for the
presence of some of these markers of celiac disease & then perform
diagnostic tests to nail it down.

Severe wheat gluten intolerance can cause classic symptoms of
schizophrenia, and amounts to about 4% of all schizophrenia diagnoses
in the U.S. These persons usually become quite normal when placed on a
gluten-free diet. Psychiatry continues to ignore this small, but
significant, population, estimated at 100,000 to 300,000 Americans.
These people are usually treated with atypical anti-psychotic
medications, but simply need a dietary change to become free of
symptoms.

Our Center has evaluated and treated nearly 20,000 persons. About 1,500
of them have reported terrible reactions to wheat and/or dairy. The
wheat/dairy sensitive population is composed of two major groups:

Group A consists of those people who are truly allergic to these foods
& must make the lifetime commitment to total avoidance of these foods.
Failure to accomplish this could result in irritability, violent
behavior, ADD, depression, anxiety, bipolar disorder, delusional
disorder, schizophrenia, not to mention malabsorption & terrible
physical health.

Group B consists of persons who have severe reactions to wheat and/or
dairy solely because of a genetic or acquired oxidative stress
condition. Fix the oxidative stress in the G.I. tract & the food
sensitivities disappear. Moreover, merely avoiding wheat/dairy will
provide only partial benefits to this group..... because the untreated
oxidative stress could result in toxic metal overload, yeast
overgrowth, copper dysregulation, weakened immune system, abnormal
levels of dopamine and norepinephrine, impaired hippocampal and
amygdala function, etc. The net result can be behavior disorders,
depression, severe mental illness, frequent infections, and an
increased tendency for cancer. Persons in Group B must have therapy
which focuses of normalizing the level of oxidative stress.

Oxidative Stress and Gastrointestinal Health

It's essential for digestive enzyme preparations to survive stomach
acid. However, digestive enzymes won't help if there is too much
oxidative stress in the gut, as this can wipe out many of the key
enzymes. Oxidative stresses often are the cause of malabsorption or
maldigestion problems. Sending in more enzymes can have limited effect
in this case. The oxidative stress would doom supplemented enzymes to
an early death. The result can be similar to Pickett's Charge at the
battle of Gettysburg: The digestive enzymes are mowed down as soon as
they enter the G.I. tract. We find that zinc therapy and
metallothionein-promotion therapy can be effective in easing oxidative
stress in the G.I. tract and overcoming these problems.

Tests for plasma zinc, serum copper and serum ceruloplasmin can give a
good indication of "metal" oxidative stress. A hair analysis for the
metals can provide some information also. A Cu/Zn ratio greater than
1.20 or an excessive amount of "unbound" copper (copper not bound to
ceruloplasmin) are indicators of excessive free radical metal ions
which can suppress or destroy many digestive enzymes, cause diarrhea,
digestive pain, maldigestion, malabsorption and multiple food
sensitivities. The Cu/Zn levels will be abnormal in the presence of
toxic overloads of mercury, cadmium, lead, antimony, etc. The toxic
metals are not the cause of the condition, but rather a consequence of
genetic abnormality in metal-metabolism.

The high incidence of oxidative stress in the G.I. tract can destroy
key digestive enzymes such as DPP-IV (needed to break down casein &
gluten). This condition is especially common in autism-spectrum
disorders.

A casein-free, gluten-free (CF/GF) diet often results in rapid striking
improvements. However, nutritional supplements, which overcome G.I.
tract oxidative stress, can make the CF/GF diet unnecessary. We've had
many patients who were extremely sensitive to dairy and wheat who did
marvelously after the CF/GF diet.
Many of these same patients completely lost their sensitivity to casein
and gluten after the antioxidant supplementation, and now can eat a
normal diet without a problem.

Normalization of zinc, metallothionein, and glutathione in the G.I.
tract isn't difficult to accomplish. It's a lot easier to take a couple
of capsules daily than this difficult diet. It takes about 6-8 weeks
for the G.I. tract to get "fixed" using this therapy.

It's becoming increasingly clear that oxidative stress has an important
role in mental illness. Since psychic stress increases oxidative stress
in the brain, sudden easing of emotional trauma would be expected to
have a direct and beneficial chemical effect on the brain.

It's true that mercury can be devastating to the brain and chelation
cleans up peripheral mercury. However, most of us have a very effective
system to protect us from mercury, namely glutathione & metallothionein
in intestinal barriers, liver, blood/brain barrier, and the brain
itself. Chelation to remove metals should be helpful only (a) in cases
involving massive poisoning by heavy metals, or (b) in cases in which
the normal protective systems fail to function properly. However,
chelation can provide 2-3 weeks of benefits just from the antioxidant
effect, whether or not there are nasty metals present.