From: Kofi on
> I am just wondering if anyone has experienced muscle twitching when your
> Crohns is flaring?

I'll skip the footnotes.

Magnesium deficiency should be at the top of your suspect list. I had
severe muscle twitching until I started taking magnesium. If this is
the cause of your problem, it's probably a disturbance in your TRPM
transporters either in the gut or kidneys. It's vital you take
magnesium with calcium and phosphorus for good absorption - but this
won't necessarily help you retain it if the transporters in your kidney
are boxed.

As far as the transporters go, you need adequate intakes or levels of
vitamin D3, omega 3 fish oils and inulin (which may ultimately indicate
butyrate) to make them work properly.

Cyclosporine A and other drugs that knock down c-Fos or EGF expression
in the gut (green tea and curcumin fall into this camp) tend to inhibit
magnesium absorption. Interfering with aldosterone, ACE or angiotensin
II might also do that.

Estrogen deficiency can cause magnesium deficiency. There's good
evidence DHEA deficiency might cause it too - pointing to a general need
for proper sympathoadrenal tone (i.e., good function in your adrenal
glands). I'm working on a paper now about that.

Oddly, some food dyes can interfere with vitamin D3 in the gut.
Brilliant Blue G blocks the cathlicidin receptor P2X7 and that then
would block EGF which you need for magnesium absorption and gut barrier
function.

I think acetyl-l-carnitine is an excellent suggestion. It can, however,
directly stoke your neurotrophins which then affects cancer risk
(raising it for some, lowering it for others) and, of course, it sends
hair follicles into premature catagen. So high doses of ALCAR (~
3g/daily) might cause hair loss and/or brain tumors. Then again,
magnesium deficiency is no picnic either. It raises substance P levels
which then exacerbates neuropathy and allergic inflammation (which
should also cause hair loss through excessive mast cell degranulation).
Other carnitines might accomplish the same goal without the same side
effects.

FYI, magnesium deficiency is a contributor to obesity, hypertension and
other metabolic diseases.
From: Beez on
On Aug 6, 12:06 pm, Kofi <k...(a)anon.un> wrote:
> FYI, magnesium deficiency is a contributor to obesity, hypertension and
> other metabolic diseases.

Kofi,

What is the best form of magnesium to supplement with?

Ever heard of Natural Calm? Do you think it is worth the extra $$$, or
are their claims just marketing hype?

TIA,
Dave
From: Joesepi on
Just stay away from massive doses of magnesium oxide unless you like bone
spurs.

"Beez" <beasdg(a)yahoo.com> wrote in message
news:41c8c01d-a987-4353-9a60-8abe7ec27423(a)l31g2000vbp.googlegroups.com...
On Aug 6, 12:06 pm, Kofi <k...(a)anon.un> wrote:
> FYI, magnesium deficiency is a contributor to obesity, hypertension and
> other metabolic diseases.

Kofi,

What is the best form of magnesium to supplement with?

Ever heard of Natural Calm? Do you think it is worth the extra $$$, or
are their claims just marketing hype?

TIA,
Dave


From: trigonometry1972 on
On Aug 6, 1:27 pm, Beez <bea...(a)yahoo.com> wrote:
> On Aug 6, 12:06 pm, Kofi <k...(a)anon.un> wrote:
>
> > FYI, magnesium deficiency is a contributor to obesity, hypertension and
> > other metabolic diseases.
>
> Kofi,
>
> What is the best form of magnesium to supplement with?
>
> Ever heard of Natural Calm? Do you think it is worth the extra $$$, or
> are their claims just marketing hype?
>
> TIA,
> Dave

I am not Kofi but I'll offer a comment or two. I'd avoid magnesium
oxide as it rather low availability. Magnesium carbonate as I recall
is pretty soluble so it should be good. A really low cost source is
epsoms salts which is magnesium sulfate plus the waters of
hydration. It is highly soluble though you'll need to keep the
magnesium doses down around a couple hundred milligrams.
An 1/8 of teaspoonful should be OK as I dimly recall.
More will loosen the stool.
It has been a long time since I've use the latter. Plus if you
take other powders that can loosen the stool this can be an issue
again by way of an additive effect.

I also have a rather inferior product on my counter that was
supposedly magnesium ascorbate but is really vitamin C crystals
with magnesium oxide. I can let this stand after I dissolve it in
water and the oxide never full dissolves to neutralize the
acidity.

Trig
From: Kofi on
In article
<41c8c01d-a987-4353-9a60-8abe7ec27423(a)l31g2000vbp.googlegroups.com>,
Beez <beasdg(a)yahoo.com> wrote:

> On Aug 6, 12:06�pm, Kofi <k...(a)anon.un> wrote:
> > FYI, magnesium deficiency is a contributor to obesity, hypertension and
> > other metabolic diseases.
>
> Kofi,
>
> What is the best form of magnesium to supplement with?

I don't know. If nothing else works, you can try I.M. shots.

> Ever heard of Natural Calm?

Nope.