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From: christkimp on 10 Sep 2008 07:32 On Sep 8, 8:29 am, maur...(a)nohost.com (Maureen) wrote: > http://www.msnbc.msn.com/id/26529310 > > Heavy teens run risk of severe liver damage > Although disease is becoming more common in obese kids, few are tested > The Associated Press > updated 12:07 p.m. MT, Sun., Sept. 7, 2008 > > TRENTON, N.J. - In a new and disturbing twist on the obesity epidemic, some > overweight teenagers have severe liver damage caused by too much body fat, > and a handful have needed liver transplants. > > Many more may need a new liver by their 30s or 40s, say experts warning > that pediatricians need to be more vigilant. The condition, which can lead > to cirrhosis and liver failure or liver cancer, is being seen in kids in > the United States, Europe, Australia and even some developing countries, > according to a surge of recent medical studies and doctors interviewed by > The Associated Press. > > The American Liver Foundation and other experts estimate 2 percent to 5 > percent of American children over age 5, nearly all of them obese or > overweight, have the condition, called nonalcoholic fatty liver disease. > > "It's clearly the most common cause of liver disease," said Dr. Ronald > Sokol, head of public policy at the liver foundation and a liver specialist > at Children's Hospital and University of Colorado Denver. > > Few given necessary test > Some experts think as many as 10 percent of all children and half of those > who are obese may suffer from it, but note that few are given the simple > blood test that can signal its presence. A biopsy is the only sure way to > diagnose this disease. > > As fat builds up, the liver can become inflamed and then scarred over time, > leading to cirrhosis, a serious condition, which in years past was mostly > caused by hepatitis or drinking too much alcohol. Liver failure or liver > cancer can follow, but if cirrhosis has not yet developed, fatty liver > disease can be reversed through weight loss. > > The disease is most common in overweight children with belly fat and > certain warning signs, such as diabetes or cholesterol or heart problems. > However, it's been seen in a few children of normal weight. > > Genetics, diet and exercise level all play a role. It is most prevalent > among Hispanics, relatively rare among African-Americans, and more common > among boys than girls. > > "There are people in their 30s or early 40s that will require a liver > transplant" from developing the condition as a kid, predicts Dr. JosDe > Derdoy, head of liver transplants at Cardinal Glennon Children's Medical > Center in St. Louis. He's treated a 15-year-old, 530-pound boy and many > others with the condition. > > 'There aren't enough livers to go around' > Experts blame obesity, with about two-thirds of all Americans overweight. > With fatty liver disease becoming more common in adults, many experts > predict it will become the top cause of liver transplants by 2020. > > "There aren't enough livers to go around," says Dr. Philip Rosenthal of the > University of California-San Francisco Children's Hospital. > > His patient, Irving Shaffino, a 15-year-old Mexican-American who lives > outside Lubbock, Texas, was lucky to get a transplant a year ago. He was in > end-stage cirrhosis and, at 5-feet-4, weighed 180 pounds. > > Irving had been fat since age 6, thanks to a high-starch, high-fat diet of > Mexican food, pizza and burgers, said his mother, Guadelupe Shaffino. At > age 8, she said, he had a distended stomach and by his early teens, > breathing problems kept him tethered to an oxygen tank at home. > > Without health insurance, the family couldn't find a local hospital that > would do a transplant. > > "My son begged me, 'Don't let me die, Mommy,' so I did everything in my > power to find a place to help him. Thanks be to God, we found a way," said > Guadelupe Shaffino, a restaurant cook. > > UCSF Children's Hospital, with money from a state health program, agreed to > do the transplant. Rosenthal, who oversees the hospital's pediatric liver > transplant program, took over care of Irving. The doctor said without a new > liver Irving would have died, maybe within months. > > "He was in bad shape," said Rosenthal. > > Soon after tests were completed and Irving got on a transplant waiting > list, an organ was found. > > "It felt like a miracle, because people say you could be on the transplant > list for years," Irving said. > > Within a couple of months of the July 26, 2007 operation, Irving had weaned > himself from the oxygen tank and could go on walks, although he got winded > quickly. > > Back home in Texas, his medications are down from 11 to four and Irving > said he's replaced soda and fast food with fruit, vegetables and whole > grains. > > "I want to get into sports again," he said. "I want to get down to maybe > 150" pounds. > > Sadly, however, Irving has made little progress in losing weight. While > he's grown an inch and a half since his operation, he's still obese and his > weight was up to 219 at the start of August. > > Specialists say many kids diagnosed with fatty liver disease come to > subsequent checkups heavier, and at best, just one in four loses > significant weight, the only treatment known to stop and even reverse the > disease. > > "My patients that are successful, the whole family has bought in," > increasing exercise and changing diet, said Dr. Stephanie Abrams, a liver > and obesity specialist at Texas Children's Hospital. "The problem is that > we aren't changing society in favor of becoming lean." > > The scope of the disease has only been realized in recent years. Just a > handful of cases were reported in medical journals in the 1980s, and in the > past, many adult patients were thought to be lying when they denied > drinking alcohol. > > 'More commonplace' > Only three liver transplants on American children with nonalcoholic fatty > liver disease were recorded from 1990 through 2002; two were done last > year. > > "It really has been only in the last two or three years that this has > become more commonplace," said Dr. Ann Scheimann, a pediatric > gastroenterologist at Johns Hopkins Children's Center. "It is scary." > > Like heart disease, liver disease is silent. Kids may feel fine for years.. > Any early symptoms, like fatigue and loss of appetite, are vague and > usually eclipsed by more conspicuous problems, from diabetes to high blood > pressure. > > "The majority of children with this still go undiagnosed," said Dr. Jeffrey > Schwimmer, head of the Fatty Liver Clinic at Rady Children's Hospital in > San Diego. "Some kids have died." > > The number of patients at his clinic has roughly tripled over its six > years, and he's seen one with cirrhosis just 8 years old. > > "Many of these children, their parents have it (fatty liver disease) and > don't know it," said Schwimmer. > > Early intervention is key > Experts say the best way to combat the problem is to intervene early, while > it can still be reversed, with a medical team working with the whole > family, including liver and hormone specialists, a dietitian and > counselors. > > This spring, the American Academy of Pediatrics recommended doctors do a > blood test of liver enzymes every two years on obese children and > overweight ones with high blood pressure or cholesterol or family history > of heart disease. A trade group for children's hospitals last year gave > similar advice. > > Within the last several months, there's been an explosion of research > published on it and the role genes may play. > > Surprisingly, some research comes from countries not known for high obesity > rates: China, India and Iran. More reports come from Australia, England, > Greece, Ireland, Israel, Italy and Japan. Doctors say globalization has > given even poor countries fast food chains and sedentary pastimes: TV, > Internet, video games. > > Scientists now are seeking the best ways to treat it. > > A small study in Rome showed weight loss helped. The U.S. government is > testing the diabetes drug metformin and vitamin E and is funding about 20 > other studies, including one that aims to determine how the disease > progresses and who is most likely to develop cirrhosis or liver failure. > > When her son was diagnosed with advanced liver disease three years ago, > Susan Siegfried recalls being "devastated." Curtis, then 12, was just over > 5-feet-5 and weighed 179 pounds. About 40 percent of his liver was scarred. > > Her husband, Mike, decreed the whole family would change its diet, and all > high-fat and junk food was removed from their home in Chester, Ill. > > Susan Siegfried said her son went from being the "sit-in-front-of-the-TV, > play-video-games kind of kid," tired and sickly, to full of energy and very > active. He now bales hay and does other chores on his uncles' nearby farm.. > Initially, he dropped about 20 pounds. He's shot up 4 inches but only > gained 8 pounds in the past two years. > > A new liver biopsy last fall showed huge improvement in his liver. > > "I'm definitely a lot thinner than I would have been if I hadn't done > anything," said Curtis, who found exercising and cutting out sugar and fat > wasn't that hard. "If you stick with it, you'll get used to it Thanks for the great reading! I really apreciated your efforts. krac(a)live.co.uk krac(a)live.co.uk
From: christkimp on 10 Sep 2008 07:33 On Sep 10, 8:32 pm, christkimp <christoper....(a)gmail.com> wrote: > On Sep 8, 8:29 am, maur...(a)nohost.com (Maureen) wrote: > > > > > > >http://www.msnbc.msn.com/id/26529310 > > > Heavy teens run risk of severe liver damage > > Although disease is becoming more common in obese kids, few are tested > > The Associated Press > > updated 12:07 p.m. MT, Sun., Sept. 7, 2008 > > > TRENTON, N.J. - In a new and disturbing twist on the obesity epidemic, some > > overweight teenagers have severe liver damage caused by too much body fat, > > and a handful have needed liver transplants. > > > Many more may need a new liver by their 30s or 40s, say experts warning > > that pediatricians need to be more vigilant. The condition, which can lead > > to cirrhosis and liver failure or liver cancer, is being seen in kids in > > the United States, Europe, Australia and even some developing countries, > > according to a surge of recent medical studies and doctors interviewed by > > The Associated Press. > > > The American Liver Foundation and other experts estimate 2 percent to 5 > > percent of American children over age 5, nearly all of them obese or > > overweight, have the condition, called nonalcoholic fatty liver disease.. > > > "It's clearly the most common cause of liver disease," said Dr. Ronald > > Sokol, head of public policy at the liver foundation and a liver specialist > > at Children's Hospital and University of Colorado Denver. > > > Few given necessary test > > Some experts think as many as 10 percent of all children and half of those > > who are obese may suffer from it, but note that few are given the simple > > blood test that can signal its presence. A biopsy is the only sure way to > > diagnose this disease. > > > As fat builds up, the liver can become inflamed and then scarred over time, > > leading to cirrhosis, a serious condition, which in years past was mostly > > caused by hepatitis or drinking too much alcohol. Liver failure or liver > > cancer can follow, but if cirrhosis has not yet developed, fatty liver > > disease can be reversed through weight loss. > > > The disease is most common in overweight children with belly fat and > > certain warning signs, such as diabetes or cholesterol or heart problems. > > However, it's been seen in a few children of normal weight. > > > Genetics, diet and exercise level all play a role. It is most prevalent > > among Hispanics, relatively rare among African-Americans, and more common > > among boys than girls. > > > "There are people in their 30s or early 40s that will require a liver > > transplant" from developing the condition as a kid, predicts Dr. JosDe > > Derdoy, head of liver transplants at Cardinal Glennon Children's Medical > > Center in St. Louis. He's treated a 15-year-old, 530-pound boy and many > > others with the condition. > > > 'There aren't enough livers to go around' > > Experts blame obesity, with about two-thirds of all Americans overweight. > > With fatty liver disease becoming more common in adults, many experts > > predict it will become the top cause of liver transplants by 2020. > > > "There aren't enough livers to go around," says Dr. Philip Rosenthal of the > > University of California-San Francisco Children's Hospital. > > > His patient, Irving Shaffino, a 15-year-old Mexican-American who lives > > outside Lubbock, Texas, was lucky to get a transplant a year ago. He was in > > end-stage cirrhosis and, at 5-feet-4, weighed 180 pounds. > > > Irving had been fat since age 6, thanks to a high-starch, high-fat diet of > > Mexican food, pizza and burgers, said his mother, Guadelupe Shaffino. At > > age 8, she said, he had a distended stomach and by his early teens, > > breathing problems kept him tethered to an oxygen tank at home. > > > Without health insurance, the family couldn't find a local hospital that > > would do a transplant. > > > "My son begged me, 'Don't let me die, Mommy,' so I did everything in my > > power to find a place to help him. Thanks be to God, we found a way," said > > Guadelupe Shaffino, a restaurant cook. > > > UCSF Children's Hospital, with money from a state health program, agreed to > > do the transplant. Rosenthal, who oversees the hospital's pediatric liver > > transplant program, took over care of Irving. The doctor said without a new > > liver Irving would have died, maybe within months. > > > "He was in bad shape," said Rosenthal. > > > Soon after tests were completed and Irving got on a transplant waiting > > list, an organ was found. > > > "It felt like a miracle, because people say you could be on the transplant > > list for years," Irving said. > > > Within a couple of months of the July 26, 2007 operation, Irving had weaned > > himself from the oxygen tank and could go on walks, although he got winded > > quickly. > > > Back home in Texas, his medications are down from 11 to four and Irving > > said he's replaced soda and fast food with fruit, vegetables and whole > > grains. > > > "I want to get into sports again," he said. "I want to get down to maybe > > 150" pounds. > > > Sadly, however, Irving has made little progress in losing weight. While > > he's grown an inch and a half since his operation, he's still obese and his > > weight was up to 219 at the start of August. > > > Specialists say many kids diagnosed with fatty liver disease come to > > subsequent checkups heavier, and at best, just one in four loses > > significant weight, the only treatment known to stop and even reverse the > > disease. > > > "My patients that are successful, the whole family has bought in," > > increasing exercise and changing diet, said Dr. Stephanie Abrams, a liver > > and obesity specialist at Texas Children's Hospital. "The problem is that > > we aren't changing society in favor of becoming lean." > > > The scope of the disease has only been realized in recent years. Just a > > handful of cases were reported in medical journals in the 1980s, and in the > > past, many adult patients were thought to be lying when they denied > > drinking alcohol. > > > 'More commonplace' > > Only three liver transplants on American children with nonalcoholic fatty > > liver disease were recorded from 1990 through 2002; two were done last > > year. > > > "It really has been only in the last two or three years that this has > > become more commonplace," said Dr. Ann Scheimann, a pediatric > > gastroenterologist at Johns Hopkins Children's Center. "It is scary." > > > Like heart disease, liver disease is silent. Kids may feel fine for years. > > Any early symptoms, like fatigue and loss of appetite, are vague and > > usually eclipsed by more conspicuous problems, from diabetes to high blood > > pressure. > > > "The majority of children with this still go undiagnosed," said Dr. Jeffrey > > Schwimmer, head of the Fatty Liver Clinic at Rady Children's Hospital in > > San Diego. "Some kids have died." > > > The number of patients at his clinic has roughly tripled over its six > > years, and he's seen one with cirrhosis just 8 years old. > > > "Many of these children, their parents have it (fatty liver disease) and > > don't know it," said Schwimmer. > > > Early intervention is key > > Experts say the best way to combat the problem is to intervene early, while > > it can still be reversed, with a medical team working with the whole > > family, including liver and hormone specialists, a dietitian and > > counselors. > > > This spring, the American Academy of Pediatrics recommended doctors do a > > blood test of liver enzymes every two years on obese children and > > overweight ones with high blood pressure or cholesterol or family history > > of heart disease. A trade group for children's hospitals last year gave > > similar advice. > > > Within the last several months, there's been an explosion of research > > published on it and the role genes may play. > > > Surprisingly, some research comes from countries not known for high obesity > > rates: China, India and Iran. More reports come from Australia, England, > > Greece, Ireland, Israel, Italy and Japan. Doctors say globalization has > > given even poor countries fast food chains and sedentary pastimes: TV, > > Internet, video games. > > > Scientists now are seeking the best ways to treat it. > > > A small study in Rome showed weight loss helped. The U.S. government is > > testing the diabetes drug metformin and vitamin E and is funding about 20 > > other studies, including one that aims to determine how the disease > > progresses and who is most likely to develop cirrhosis or liver failure.. > > > When her son was diagnosed with advanced liver disease three years ago, > > Susan Siegfried recalls being "devastated." Curtis, then 12, was just over > > 5-feet-5 and weighed 179 pounds. About 40 percent of his liver was scarred. > > > Her husband, Mike, decreed the whole family would change its diet, and all > > high-fat and junk food was removed from their home in Chester, Ill. > > > Susan Siegfried said her son went from being the "sit-in-front-of-the-TV, > > play-video-games kind of kid," tired and sickly, to full of energy and very > > active. He now bales hay and does other chores on his uncles' nearby farm. > > Initially, he dropped about 20 pounds. He's shot up 4 inches but only > > gained 8 pounds in the past two years. > > > A new liver biopsy last fall showed huge improvement in his liver. > > > "I'm definitely a lot thinner than I would have been if I hadn't done > > anything," said Curtis, who found exercising and cutting out sugar and fat > > wasn't that hard. "If you stick with it, you'll get used to it > > Thanks for the great reading! I really apreciated your efforts. > krac(a)live.co.uk > krac(a)live.co.uk- Hide quoted text - > > - Show quoted text - I wnated that to show monkey
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