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Increasing infections...
Archives of Internal Medicine 2010;170(4):347-353 "Clinical and Economic Outcomes Attributable to Health Care-Associated Sepsis and Pneumonia" It is my hypothesis that the "secular trend," the increase in size and earlier puberty occurring in children, is caused by an increase in the percentage of individuals ... 27 Feb 2010 18:50
Schizophrenia vs. Celiac: different sets of antibodies to wheat?
A link between Celiac and schizophrenia has been postulated before. Some schizophrenics have even been cured with a gluten-free diet. Now we have evidence that Celiac and some forms of schizophrenia may both be driven by antibodies to different antigen targets in wheat. Given that wheat, rice, red meat and c... 20 Feb 2010 12:27
Antibodies, sympathetic drive and the development of Type I diabetes
I think the lack of specific antibodies against infectious diseases may indicate a failure of sympathetic-mediated immune responses. In M.S., it looks like a history of sympathetic overdrive is protective - a previous TB infection, for example. This study pointing to the lack of antibodies with Type I diabete... 20 Feb 2010 03:42
Infectious diseases induce anti-TG antibodies, similar to Celiac
Further fleshing out this line of thought... Clin Exp Immunol. 2010 Feb;159(2):217-23. Epub 2009 Nov 12. � Anti-transglutaminase antibodies in non-coeliac children suffering from infectious diseases. Ferrara F, Quaglia S, Caputo I, Esposito C, Lepretti M, Pastore S, Giorgi R, Martelossi S, Dal Molin G, Di To... 20 Feb 2010 04:49
Could Celiac anti-TG autoantibodies cause Crohn's-like colitis by impairing macrophages?
If you've followed my posts in, you know there is plenty of evidence piling up that Crohn's is due to defective innate immunity. Innate pathways that synthesize antimicrobials like cathelicidin are defective via impaired butyrate uptake or low levels of Vitamin D3 - sometimes even hi... 20 Feb 2010 01:30
PPARalpha stimulation limits lymphocyte proliferation
As I pointed out several years ago, the mu opioid/cannabinoid complex is under epigenetic control (via OCTN2/butyrate/carnitine uptake) and there was evidence even back then that cannabinoid signals limited lymphocyte proliferation. Now we have more direct evidence of this via PPARalpha, a regulator of OCTN2. ... 18 Feb 2010 07:15
Order Affordable Health Insurance Online without an Agent
Order Affordable Health Insurance Online without an Agent People with pre-existing conditions can also get covered. Watch Video Details at: Order Major Medical Coverage at: or Call for Assistance: 641-715-3900 ext. 30782 Quit ... 14 Feb 2010 03:04
Folic acid receptor antibodies, vitamin D3 and milk consumption in autoimmune disease
For Kofi: Some articles on folic acid metabolism, its relation to cancer, and some related patents: http://www.patentsto... 8 Feb 2010 22:36
Restorative yoga
You know when you feel exhausted all the time and keep on having low grade infections or chronic pain that no amount of therapy will shift? ... 4 Feb 2010 11:12
The role of SIRT6, glucose metabolism, lifespan and inflammation
Nicotinamide phosphoribosyltransferase (Nampt) inhibitors such as FK866 are potent inhibitors of NAD+ synthesis that show promise for the treatment of different forms of cancer. Based on Nampt upregulation in activated T lymphocytes and on preliminary reports of lymphopenia in FK866 treated patients, we have in... 25 Jan 2010 21:53
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