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Fasting (via FOXO) upregulates innate antimicrobials like cathelicidin
Fasting upregulates innate antimicrobials? Well, you heard it from me first. I stated quite a while back that fasting upregulates OCTN2 and this should, in turn, upregulate carnitine uptake, butyrate uptake and histone acetylation leading to enhanced expression of those genes under HDAC control - including de... 24 Jan 2010 03:35
The TLR2/macrophage/sympathetic response inhibits autoimmunity/promotes self-tolerance
This provides the final pieces of evidence in a relationship I've suspected for a few years now. The macrophage/TLR2/TLR4/sympathetic nervous system suppresses autoimmunity directly through means like IL-10 secretion. Dysfunction in this system - whether via defects in the TLR2/macrophage signal cascade or vi... 22 Jan 2010 23:04
FREE Animations you can e-mail
FREE Animations you can e-mail (click link): THOUSANDS of FREE Animations Enjoy, Fitz ... 21 Jan 2010 18:06
bleeding hemorrhoids not dangerous?
I was reading that people seem to think that bleeding hemorrhoids are not dangerous. However, the bleeding is happening in a spot where there are alot more bacteria than other parts of the body. Also, it seems that the membranes of the intestines are almost as permeable as the nose which is why suppositories ar... 10 Jan 2010 06:25
HDAC1 upregulation in neurodegneration impairs neuronal mitochondrial transport
This points to a defective OCTN2/carnitine/butyrate uptake mechanism which perhaps accounts for the gender bias in multiple sclerosis. Testosterone is a carnitine transporter and given how the movement of mitochondria is vital in neurotransmission, this might help link testosterone and NGF signaling. In any c... 3 Jan 2010 07:17
SDF-1alpha as an immunosuppressant
J Exp Med. 2008 Oct 27;205(11):2643-55. Epub 2008 Oct 13. CXCL12 (SDF-1alpha) suppresses ongoing experimental autoimmune encephalomyelitis by selecting antigen-specific regulatory T cells. Meiron M, Zohar Y, Anunu R, Wildbaum G, Karin N. Department of Immunology, Bruce Rappaport Faculty of Medicine, Technion, ... 23 Dec 2009 21:52
Scar/Cicatrix Healing?
Hello, Simplly, I want o know, How our body system can resist scar formaton and can remove formed scar? Can our medical interventions in natural healing cause scar formations? Whether scars are formed in all other species? Best wishes. ... 21 Dec 2009 23:34
I wonder who tested the shots and found them to be too weak? The kids? .........Trig ... 16 Dec 2009 04:44
"800,000 doses of kids’ H1N1 vaccine recalled" "Tests show the shots may not be potent enough to protect against virus" December 15, 2009 updated 2 hours, 7 minutes ago ATLANTA - Hundreds of thousands of swine flu shots for children have been recalled because tests indicate the vaccine dose... 15 Dec 2009 15:38
Thinking SWINE FLU Vaccine? How About A Guillain-Barré [GEE-yan bah-RAY] Syndrome SURPRISE?
Uh, but we don't wish to put a crimp in your mobility ... just a few thoughts ... ------------------------ "Is there a history lesson from the swine flu of '76?" "Scientists look closely for side effects of vaccine after earlier version caused outbreak of rare form of paralysis" By David Brown Saturday, No... 28 Nov 2009 13:29
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