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From: Gloria Koshinski on 3 Jul 2008 08:40
An update on husband with colon cancer, stage 4 with mets to lungs and lymph
nodes. Got the results of last scan and not good. The chemo is no longer
working after almost a year. Tumors are now growing so stopping it for 4
weeks total then starting a new trial with Folfiri and if he is in the 50%
lucky portion he will also receive Aflibercept. This is a drug company trial
but at this stage we don't care. According to the onc. Folfiri is the next
thing she would use anyway so this way he has a 50% chance of getting the
new drug compared to no chance without the trial. Next Wednesday we go and
get more blood work done and an EKG to make sure no heart problems, then the
following week if he is accepted we will start the chemo again. Keeping our
fingers crossed and a lot of prayer in our hearts. Also I had read about a
new treatment going on in Cuba where they take blood from young healthy
volunteers with a lot of cancer fighting cells and inject it into cancer
patients. Didn't book mark it and was wondering if somebody had it. Don't
remember if it was this list that had it or one of the others I read. Thanks
for listening and any help you can give.

From: J on 3 Jul 2008 17:27
Gloria Koshinski wrote:

> An update on husband with colon cancer, stage 4 with mets to lungs and lymph
> nodes. Got the results of last scan and not good. The chemo is no longer
> working after almost a year. Tumors are now growing so stopping it for 4
> weeks total then starting a new trial with Folfiri and if he is in the 50%
> lucky portion he will also receive Aflibercept. This is a drug company trial
> but at this stage we don't care. According to the onc. Folfiri is the next
> thing she would use anyway so this way he has a 50% chance of getting the
> new drug compared to no chance without the trial. Next Wednesday we go and
> get more blood work done and an EKG to make sure no heart problems, then the
> following week if he is accepted we will start the chemo again. Keeping our
> fingers crossed and a lot of prayer in our hearts. Also I had read about a
> new treatment going on in Cuba where they take blood from young healthy
> volunteers with a lot of cancer fighting cells and inject it into cancer
> patients. Didn't book mark it and was wondering if somebody had it. Don't
> remember if it was this list that had it or one of the others I read. Thanks
> for listening and any help you can give.

Hello Gloria,
The Cuban one did not mention colon cancer; only NSCLC (lung cancer), melanoma
and glioblastoma.

There are other vaccine studies, some of which involve colon and some of which
are in the US.
Search on montanide http://clinicaltrials.gov/ct2/results?term=montanide&pg=2
Found 43 studies with search of: montanide | Open Studies
Click on "Hide studies that are not seeking new volunteers. " then look through
the summaries for colon.

http://clinicaltrials.gov/ct2/results?term=vaccine+AND+colon
Found 42 studies with search of: vaccine AND colon
Click on "Hide studies that are not seeking new volunteers. " then look at the
details of each..

http://clinicaltrials.gov/ct2/results?term=immunotherapy+AND+colon
Found 20 studies with search of: immunotherapy AND colon
Click on "Hide studies that are not seeking new volunteers. " then look at the
details of each..

There may be some duplicates; but looking through will show you what's available
now, in the US and elsewhere.
If you find something interesting which may apply to your husband, save it
without a bunch of letters/number after, just the "simple" study number :
Example:http://clinicaltrials.gov/ct2/show/NCT00656123?term=vaccine+AND+colon&recr=Open&rank=1

So I remove the question mark and what follows that to become
http://clinicaltrials.gov/ct2/show/NCT00656123
I'm not saying that's the right one for your husband, just showing how to clean
up the study url.

The people or places to contact about what is or isn't available with the Cuban
one may be on this report
http://jco.ascopubs.org/cgi/content/abstract/26/9/1452

Best of luck with your husband's new regimen.
J


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