From: Robert W. McAdams on
David wrote:
> Dr. Zarkov wrote:
>
>
>>The government has no ethical right to dictate what we can and cannot
>>put into our own bodies in any case.
>
>
>
> Maybe in principle.............*if* everyone had the necessary amount
> of medical knowledge for making intelligent decisions about what they
> put in their bodies. But in practice, there are a lot of gullible and
> medically uneducated people out there who *need* to be protected from
> certain products which may have dangerous side effects which are not
> mentioned in marketing claims (at least the TV commercials for
> pharmaceuticals have to list the most common and/or dangerous adverse
> effects!!!). People without a medical or science degree don't deserve
> to be harmed just because they don't have such an education.

I agree. But the question is why this protection couldn't be achieved
simply by requiring such products to carry a prominent warning whose
text would be written by the FDA. Are the potential side effects of the
lovastatin in red yeast rice really more serious than those of the
tobacco in cigarettes (which are sold with a warning label).


Bob

From: Chuck on
Is the chemical in Red Yeast Rice identical to lovastatin? If so, how
much is there? Enough to cause the liver toxicity that statin drugs
can, or just trace amounts? I can't take statins. I use Welchol but I
am interested in adding another non-toxic substance if anyone has any
ideas. Chuck

Robert W. McAdams wrote:
> David wrote:
> > Dr. Zarkov wrote:
> >
> >
> >>The government has no ethical right to dictate what we can and cannot
> >>put into our own bodies in any case.
> >
> >
> >
> > Maybe in principle.............*if* everyone had the necessary amount
> > of medical knowledge for making intelligent decisions about what they
> > put in their bodies. But in practice, there are a lot of gullible and
> > medically uneducated people out there who *need* to be protected from
> > certain products which may have dangerous side effects which are not
> > mentioned in marketing claims (at least the TV commercials for
> > pharmaceuticals have to list the most common and/or dangerous adverse
> > effects!!!). People without a medical or science degree don't deserve
> > to be harmed just because they don't have such an education.
>
> I agree. But the question is why this protection couldn't be achieved
> simply by requiring such products to carry a prominent warning whose
> text would be written by the FDA. Are the potential side effects of the
> lovastatin in red yeast rice really more serious than those of the
> tobacco in cigarettes (which are sold with a warning label).
>
>
> Bob

From: Juhana Harju on
Rouz wrote:
Tim Campbell wrote:

:: High Cholesterol: Red Yeast Rice is Better, Safer, and Cheaper
::
:: Dr. Wright sounds off on Red Yeast Rice
::
:: The drug giants knew they'd be in trouble if word got out about red
:: yeast rice...
::
:: Not only did studies show that this ancient Asian edible slashed
:: cholesterol an average of 40 points in just 3 months, it did so
:: without any side effects whatsoever. What's more, it was growing more
:: and more widely available, for far less money than statin drugs - and
:: without the need for a prescription...
::
:: So what did those fat-cat drug executives do? They went to court...
::
:: Their "grounds" for suing? Red yeast rice extract contains a natural
:: form of lovastatin , the same active ingredient found in patented
:: Mevacor, one of the major cholesterol drugs...
::
:: The first time the drug companies took red yeast rice makers to court,
:: however, the judge quite rightly threw the case out . But the
:: pharmaceutical industry's deep pockets ensured that they'd be able to
:: press the case until they got what they wanted. After appealing, they
:: got their verdict...
::
:: And with one stroke of the gavel, makers of safe, natural,
:: un-patent-able red yeast rice extract suddenly found themselves in
:: violation of Federal law.
::
:: When the decision was handed down, the FDA was waiting in the wings.
:: As though on command from the patent-drug cartel, they quickly banned
:: red yeast rice extract from stores, mail-order sellers and all other
:: sources - before its makers could regroup and file an appeal or suit
:: of their own.
::
:: http://jeffsutherland.com/complementary/

: Lovastatin is an extremely powerful and useful drug. It extends life
: for many users.
:
: However, like many powerful drugs it will cause dangerous side
: effects in a small portion of users.
:
: Since Red Yeast Rice extract contains Lovastatin, it must be assumed
: that Red Yeast Rice extract will cause the same dangerous side effects
: as Lovastatin in some small portion of users, especially since the
: Lovastatin content in the extract is neither controlled or monitored.
:
: Therefore, drugs such as Lovastatin or Red Yeast Rice extract must be
: taken by knowledgeable persons, or under the supervision of
: knowledgeable persons. Most non-medical users are not sufficiently
: knowledgeable. Therefore, we restrict such drugs to dispensation
: via prescription and regulate the manufacturers stringently.

Lovastatin and red yeast rice are not exactly same as fermentation of rice
produces a whole family of compounds called monacolins. "One of these
compounds called Monacolin K was isolated by a drug manufacturer from a
different species by a drug manufacturer from a different species of fungus
and purified and crystallized to purity. The drug, Mevacor (Merck) initiated
a generation of medical research that has developed many drugs in the
category called statins through novel chemical modifications. These drugs
have been shown to reduce mortality from heart disease and may someday have
benefits for bone disease and cancer. The key difference between drugs and
herbs is that herbs are a combination of multiple compounds while drugs
consist of a single purified crystallized compound. Our research shows that
only 5 mg of Monacolin K in the matrix of this yeast has the same
cholesterol-lowering effect as 20 mg of Mevacor demonstrating that the
entire family of compounds has an effect not just the one species which
became a drug."

http://www.cancercurecoalition.org/articles/nutritionandcancer2.html

Still I do agree that the concerns of statin adverse effects apply to red
yeast rice as well.

--
Juhana


From: David on

Robert W. McAdams wrote:
> Are the potential side effects of the
> lovastatin in red yeast rice really more serious than those of the
> tobacco in cigarettes (which are sold with a warning label)?


Potentially yes, albeit rarely. Rhabdomyolysis is an acute and
life-threatening side effect of statin compounds. I don't know if
there are any documented cases of it in persons taking red yeast rice,
but it's certainly possible and should be investigated thoroughly. A
prominent warning label would be a good start, at the very least.

From: backon on
In article <1153060898.891027.298140(a)b28g2000cwb.googlegroups.com>, "David" <david.sprouse(a)gmail.com> writes:
>
> Robert W. McAdams wrote:
>> Are the potential side effects of the
>> lovastatin in red yeast rice really more serious than those of the
>> tobacco in cigarettes (which are sold with a warning label)?
>
>
> Potentially yes, albeit rarely. Rhabdomyolysis is an acute and
> life-threatening side effect of statin compounds. I don't know if
> there are any documented cases of it in persons taking red yeast rice,
> but it's certainly possible and should be investigated thoroughly. A
> prominent warning label would be a good start, at the very least.


L-carnitine has been found to prevent the statin-induced myopathy.
See: Improvement of statin-associated myotoxicity by L-carnitine.
J Thromb Haemost. 2004 Dec;2(12):2270-1

Josh


>