From: Mike on
Mark Probert wrote:
> On Oct 18, 9:46 am, bigvince <vince.mirag...(a)> wrote:
>> Not really......
>> Probably not.
> This is precisely why people who come in contact with the elderly, ill
> and immunocompromised should be vaccinated against the flu, i.e. to
> prevent infecting the elderly, ill and immunocompromised.

Yep, mandate flu vaccinations for their children, grandchildren,
great-grandchildren, home attendants, pharmacists, grocers etc and
soon that will cover everyone - a vax flack dream. But would it help?

"Only four studies were properly designed to pin down the
effectiveness of flu vaccine, [epidemiologist Tom Jefferson] says, and
two of those showed that it might be effective in certain groups of
patients, such as school-age children with no underlying health issues
like asthma. The other two showed equivocal results or no benefit."

>> Cochrane Database Syst Rev. 2006 Jul 19;3:CD004876.Click here to read
>> Substance (MeSH Keyword), Cited in PMC
>> Vaccines for preventing influenza in the elderly.
>> Rivetti D, Jefferson T, Thomas R, Rudin M, Rivetti A, Di Pietrantonj
>> C, Demicheli V.
>> Servizio di Igiene e Sanita' Pubblica, Public Health Department, ASL
>> 19 Asti, C. so Dante 202, Asti, Italy 14100..........
>> BACKGROUND: Influenza vaccination of elderly individuals is
>> recommended worldwide and has been targeted toward the elderly and
>> those at serious risk of complications. OBJECTIVES: Our aim was to
>> review the evidence of efficacy, effectiveness and safety of influenza
>> vaccines in individuals aged 65 years or older.......
>> ....SELECTION CRITERIA: We considered randomised, quasi-randomised,
>> cohort and case-control studies assessing efficacy against influenza
>> (laboratory-confirmed cases) or effectiveness against influenza-like
>> illness (ILI)...
>> .....MAIN RESULTS: Sixty-four studies were included in the efficacy /
>> effectiveness assessment, resulting in 96 data sets. In homes for
>> elderly individuals (with good vaccine match and high viral
>> circulation) the effectiveness of vaccines against ILI was 23% (6% to
>> 36%) and non-significant against influenza (RR 1.04: 95% CI 0.43 to
>> 2.51)....
>> ........In elderly individuals living in the community, vaccines were
>> not significantly effective against influenza (RR 0.19; 95% CI 0.02 to
>> 2.01), ILI (RR 1.05: 95% CI 0.58 to 1.89), or pneumonia (RR 0.88; 95%
>> CI 0.64 to 1.20). Well matched vaccines prevented hospital admission
>> for influenza and pneumonia (VE 26%; 12% to 38%) and all-cause
>> mortality (VE 42%; 24% to 55%).....
>> ......AUTHORS' CONCLUSIONS: In long-term care facilities, where
>> vaccination is most effective against complications, the aims of the
>> vaccination campaign are fulfilled, at least in part. However,
>> according to reliable evidence the usefulness of vaccines in the
>> community is modest. The apparent high effectiveness of the vaccines
>> in preventing death from all causes may reflect a baseline imbalance
>> in health status and other systematic differences in the two groups of
>> participants.
>> PMID: 16856068 [PubMed -
>> How does a flu shot that does not protect against the flu reduce the
>> complications of the flu?
>> 'The apparent high effectiveness of the vaccines in preventing death
>> from all causes may reflect a baseline imbalance in health status and
>> other systematic differences in the two groups of participants.'
>> 1: Lancet Infect Dis. 2007 Oct;7(10):658-66....
>> Mortality benefits of influenza vaccination in elderly people: an
>> ongoing controversy.
>> Simonsen L, Taylor RJ, Viboud C, Miller MA, Jackson LA.
>> National Institute of Allergy and Infectious Diseases, National
>> Institutes of Health, Bethesda, MD, USA. iph...(a)
>> Influenza vaccination policy in most high-income countries attempts to
>> reduce the mortality burden of influenza by targeting people aged at
>> least 65 years for vaccination. However, the effectiveness of this
>> strategy is under debate........
>> .......Recent excess mortality studies were unable to confirm a
>> decline in influenza-related mortality since 1980, even as vaccination
>> coverage increased from 15% to 65%. Paradoxically, whereas those
>> studies attribute about 5% of all winter deaths to influenza, many
>> cohort studies report a 50% reduction in the total risk of death in
>> winter--a benefit ten times greater than the estimated influenza
>> mortality burden. New studies, however, have shown substantial
>> unadjusted selection bias in previous cohort studies........
>> ....We conclude that frailty selection bias and use of non-specific
>> endpoints such as all-cause mortality have led cohort studies to
>> greatly exaggerate vaccine benefits. The remaining evidence base is
>> currently insufficient to indicate the magnitude of the mortality
>> benefit, if any, that elderly people derive from the vaccination
>> programme.
>> PMID: 17897608 [PubMed - indexed for MEDLINE]
From: t on

"Happy Oyster" <happy.oyster(a)> wrote in message news:0jnnd5tmkv