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From: Chip on 4 May 2008 16:18

"Irishgirl" <LSCARTER08(a)gmail.com> wrote in message
news:a31ed243-7d81-42c1-80ca-5f9c141dc3a3(a)m3g2000hsc.googlegroups.com...
> I am currently on Effexor XR 300mg, Risperdal 2mg , xanax 1.5 mg per
> day, I have been on these meds for about 10 years and they did help.
> However in the last 6 months I have had more panic attacks and severe
> depression to include suicidal thoughts. I have been seeing a doctor
> and schedule to go on May 7th something has to change or I am not
> going to make it
>
> My questions is do you become immune to anti depressant medications,
> dose it stop working for you?

they can become less effective with time, so that one has breakthrough
symptoms.

> I am wondering why I am feeling so bad when the meds helped me before
> The only thing that has changed is more stress due to illness in the
> family. I am trying to cope,

Your worsening depression could be cause the meds are less effective, or
you have more stress, or a combo of both.

Which brings up an interesting question: what are the non-med things a
person can do to cope better?

Maybe someone can jump in and give some suggestions.

Jogging always helped me with depression and feeling better.

Chip



From: Chip on 4 May 2008 16:21

"Erin" <squiggle(a)sympatico.ca> wrote in message
news:f21568a5-6635-4fa5-8166-ba0b2d2a0234(a)l42g2000hsc.googlegroups.com...
>
>
> Irishgirl wrote:
> > I am currently on Effexor XR 300mg, Risperdal 2mg , xanax 1.5 mg per
> > day, I have been on these meds for about 10 years and they did help.
> > However in the last 6 months I have had more panic attacks and severe
> > depression to include suicidal thoughts. I have been seeing a doctor
> > and schedule to go on May 7th something has to change or I am not
> > going to make it
> >
> > My questions is do you become immune to anti depressant medications,
> > dose it stop working for you?
> > I am wondering why I am feeling so bad when the meds helped me before
> > The only thing that has changed is more stress due to illness in the
> > family. I am trying to cope,
> >
> > Any feed back would be appreciated
> >
> > Irishgirl
>
>
> I can't speak for the antidepressants as they are not classified
> as addicting, but from personal experience i can say for sure that
> being on Xanax for 10 yrs. at 1.5 may go past tolerance and into
> withdrawals.

How can one suffer withdrawal from Xanax if they're still taking it?

I've been on Klonopin for 21 years and the only time I had withdrawal
symptoms was when I tapered completely off the KLonopin.

Chip



From: Erin on 4 May 2008 19:11


Chip wrote:
> "Erin" <squiggle(a)sympatico.ca> wrote in message
> news:f21568a5-6635-4fa5-8166-ba0b2d2a0234(a)l42g2000hsc.googlegroups.com...
> >
> >
> > Irishgirl wrote:
> > > I am currently on Effexor XR 300mg, Risperdal 2mg , xanax 1.5 mg per
> > > day, I have been on these meds for about 10 years and they did help.
> > > However in the last 6 months I have had more panic attacks and severe
> > > depression to include suicidal thoughts. I have been seeing a doctor
> > > and schedule to go on May 7th something has to change or I am not
> > > going to make it
> > >
> > > My questions is do you become immune to anti depressant medications,
> > > dose it stop working for you?
> > > I am wondering why I am feeling so bad when the meds helped me before
> > > The only thing that has changed is more stress due to illness in the
> > > family. I am trying to cope,
> > >
> > > Any feed back would be appreciated
> > >
> > > Irishgirl
> >
> >
> > I can't speak for the antidepressants as they are not classified
> > as addicting, but from personal experience i can say for sure that
> > being on Xanax for 10 yrs. at 1.5 may go past tolerance and into
> > withdrawals.
>
> How can one suffer withdrawal from Xanax if they're still taking it?

Because the dose becomes less effective as time goes by; it has
all the common addicting properties; as far as your body is
concerned your 1.5 is no longer pacifying the GABA receptors;
you need more or to withdraw to stop the withdrawals. Valium and most
benzos
are the same but not Klonopin. I have switched the Klonopin dose
about 3 times
in my life, taking it for close to 20 yrs. It is an uncommon benzo.

Erin
>
> I've been on Klonopin for 21 years and the only time I had withdrawal
> symptoms was when I tapered completely off the KLonopin.
>
> Chip
From: Nom dePlume on 4 May 2008 20:08


"Chip" <no_spam_chipmonk___36(a)hotmail.com> wrote in message
news:fvl5nc$b86$1(a)aioe.org...
>
> "Irishgirl" <LSCARTER08(a)gmail.com> wrote in message
> news:a31ed243-7d81-42c1-80ca-5f9c141dc3a3(a)m3g2000hsc.googlegroups.com...
>> I am currently on Effexor XR 300mg, Risperdal 2mg , xanax 1.5 mg per
>> day, I have been on these meds for about 10 years and they did help.
>> However in the last 6 months I have had more panic attacks and severe
>> depression to include suicidal thoughts. I have been seeing a doctor
>> and schedule to go on May 7th something has to change or I am not
>> going to make it
>>
>> My questions is do you become immune to anti depressant medications,
>> dose it stop working for you?
>
> they can become less effective with time, so that one has breakthrough
> symptoms.
>
>> I am wondering why I am feeling so bad when the meds helped me before
>> The only thing that has changed is more stress due to illness in the
>> family. I am trying to cope,
>
> Your worsening depression could be cause the meds are less effective, or
> you have more stress, or a combo of both.
>
> Which brings up an interesting question: what are the non-med things a
> person can do to cope better?
>
> Maybe someone can jump in and give some suggestions.
>
> Jogging always helped me with depression and feeling better.
>
> Chip

As Chip says, the benefits of particular antidepressants do decrease over
time for some people. In your case, I'd guess that either this process, or
your increased stress, or a combination could be responsible for your
worsening symptoms.

The usual medical approach for this kind of thing is to increase the dosage
of your antidepressant, or switch to another one. You are doing the right
thing in going to see your doctor about the problem.
--
Nom dePlume, Ph.D.
Why, yes, in fact, I am a rocket scientist.

Find my book, Medicines for Mental health, and free drug information, at
www.MentalMeds.org

=====


From: Chip on 6 May 2008 14:31

"Erin" <squiggle(a)sympatico.ca> wrote

> > How can one suffer withdrawal from Xanax if they're still taking it?
>
> Because the dose becomes less effective as time goes by;


In 1992 Romach and colleagues reported that dose escalation was not a
characteristic of long-term alprazolam users, and the majority of patients
indicated that alprazolam continued to be effective. [45]

A 2003 study did not support the hypothesis that long-term use of
benzodiazepines frequently results in notable dose escalation. [46]

In a 1-year follow-up study of patients with panic disorder continuing
treatment with clonazepam, 90% maintained a positive response without
developing significant tolerance. In a 2.5-year follow-up study of
alprazolam therapy, little evidence of tolerance emerged. [47]

^ Romach MK, Somer GR, Sobell LC, Sobell MB, Kaplan HL, Sellers EM (1992).
"Characteristics of long-term alprazolam users in the community". J Clin
Psychopharmacol 12 (5): 316-21. PMID 1479048.

^ Soumerai SB, Simoni-Wastila L, Singer C, et al (2003). "Lack of
relationship between long-term use of benzodiazepines and escalation to
high dosages". Psychiatr Serv 54 (7): 1006-11. PMID 12851438.

^ Pollack MH (1990). "Long-term management of panic disorder". J Clin
Psychiatry 51 Suppl: 11-3; discussion 50-3. PMID 1970813.





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