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From: sheder1 on 1 Aug 2008 16:11
Czech anti-cancer drug put to the test
By ÈTK / Published 1 August 2008

Antonín Holý also developed a drug that helps combat AIDS.


Prague, July 31 (CTK) - The haematological oncological clinic of
Teaching Hospital in Brno started testing an anti-cancer substance
developed by Czech chemist Professor Antonin Holy, Hospodarske noviny
(HN) wrote Thursday.

Probably tens of Czech patients will participate in the clinical tests
of the preparation against lymphatic nodes and chronic leukaemia
cancer that U.S. firm Gilead Sciences has produced from Holy's
effective substance GS-9219, HN writes.

It says further Czech clinics in Prague, Hradec Kralove and Olomouc
will join Brno in the course of August.

Testing the new medicine is much cheaper in the Czech Republic than in
the United States, Jiri Vorlicek, chairman of the Czech Oncological
Society, is quoted as saying.

Besides, Czech hospitals have experience with international

tests, the paper writes.

It says the Americans will spend 11 billion crowns on the tests in
people.

The main advantage of the effective substance, developed in the
Organic Chemistry and Biochemistry Institute, is that it does not harm
healthy cells, HN writes.

The current stage is to check whether the substance can be applied to
people at all. It has been successfully tested in dogs in the United
States.

If the first clinical tests that can last about a year are successful,
second and third testing in which the substance's efficacy is checked
could follow, HN writes.

It says, however, the medicine could only reach the market after
several years if the tests are successful.

It says one quarter of people who fall ill with cancer in the Czech
Republic annually have tumours of lymphatic nodes or chronic
leukaemia.

The paper writes that Holy previously participated in the preparation
of substances for five viral medicines that today help HIV and
hepatitis patients.

He signed a five-year agreement with the Americans two years ago that
provides his institute with one million dollars annually, HN writes.
From: J on 2 Aug 2008 05:31
sheder1 wrote:

> Czech anti-cancer drug put to the test
> By �TK / Published 1 August 2008
>
> Anton�n Hol� also developed a drug that helps combat AIDS.
>
> Prague, July 31 (CTK) - The haematological oncological clinic of
> Teaching Hospital in Brno started testing an anti-cancer substance
> developed by Czech chemist Professor Antonin Holy, Hospodarske noviny
> (HN) wrote Thursday.
>
> Probably tens of Czech patients will participate in the clinical tests
> of the preparation against lymphatic nodes and chronic leukaemia
> cancer that U.S. firm Gilead Sciences has produced from Holy's
> effective substance GS-9219, HN writes.
>
> It says further Czech clinics in Prague, Hradec Kralove and Olomouc
> will join Brno in the course of August.
>
> Testing the new medicine is much cheaper in the Czech Republic than in
> the United States, Jiri Vorlicek, chairman of the Czech Oncological
> Society, is quoted as saying.
>
> Besides, Czech hospitals have experience with international
> tests, the paper writes.
>
> It says the Americans will spend 11 billion crowns on the tests in
> people.
>
> The main advantage of the effective substance, developed in the
> Organic Chemistry and Biochemistry Institute, is that it does not harm
> healthy cells, HN writes.

That has yet to be proven
http://clinicaltrials.gov/ct2/show/related/NCT00499239 ; but great news
for people of another newsgroup. http://www.radio.cz/en/article/81290

maybe the Czechs will use the money for radiation treatment equipment.
http://www.praguepost.com/articles/2007/12/26/czech-republic-lags-in-cancer-treatment.php

J

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