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From: kumar on 14 Dec 2005 23:22 "Cancer Causes Tumors are caused by mutations in DNA of cells. An accumulation of mutations is needed for a tumor to emerge. Mutations that activate oncogenes or repress tumor supressor genes can eventually lead to tumors. Cells have mechanisms that repair DNA and other mechanisms that cause the cell to destroy itself by apoptosis if DNA damage gets too severe. Mutations that repress the genes for these mechanisms can also eventually lead to cancer. A mutation in one oncogen or one tumor repressor gene is usually not enough for a tumor to occur. A combination of a number of mutations is necessary. DNA microarrays can be used to determine if oncogenes or tumor repressor genes have been mutated. Possibly in the future tumors can be treated better by using DNA microarrays to determine the exact characteristics of the tumor. http://en.wikipedia.org/wiki/Tumor " "Tumor antigens Tumor antigens are those antigens that are presented by the MHC I molecules on the surface of tumor cells. These antigens can sometimes be presented only by tumor cells and never by the normal ones. In this case, they are called tumor-specific antigens and typically result from a tumor specific mutation. More common are antigens that are presented by tumor cells and normal cells, and they are called tumor-associated antigens. Cytotoxic T lymphocytes that recognized these antigens may be able to destroy the tumor cells before they proliferate or metastasize. Tumor antigens can also be on the surface of the tumor in the form of, for example, a mutated receptor, in which case they will be recognized by B cells. http://en.wikipedia.org/wiki/Antigen#Tumor_antigens " Hello, The following two factors as mentioned in above links are important for reversal of cancer cells or cancer cure:- "Cells have mechanisms that repair DNA and other mechanisms that cause the cell to destroy itself by apoptosis if DNA damage gets too severe. Mutations that repress the genes for these mechanisms can also eventually lead to cancer." "Tumor antigens are those antigens that are presented by the MHC I molecules on the surface of tumor cells. These antigens can sometimes be presented only by tumor cells and never by the normal ones. In this case, they are called tumor-specific antigens and typically result from a tumor specific mutation.." I want to know that:- 1. Can cancer cells be mediated/encouraged to reverse/supress their DNA damages? If yes, how? 2. Can cancer cells be mediated/encouraged to produce tumor-specific antigens or mutations/cancer specific antigens? How? In short I want to know the possibilities of that, can cancer or maligencies be reversed by any mean instead of killing cancer cells by medical aid? I have some clues(CAMs based) that fluorine, sulphur and silicon as cal.fluoride, cal.sulphate, pot.sulphate and silicic acid may have some relations to it. Best wishes.
From: Mike McWilliams on 15 Dec 2005 11:31 kumar wrote: > I want to know that:- > > > 1. Can cancer cells be mediated/encouraged to reverse/supress their DNA > > damages? If yes, how? If DNA damage has been passed down to a few generations, and you have a clump of a million cancer cells with the same sequence damaged, you will probably not be able to reverse the damage. It may be possible one day with gene therapy, but I wouldn't bet on that. > > > 2. Can cancer cells be mediated/encouraged to produce tumor-specific > antigens or mutations/cancer specific antigens? How? > > Not really, either the damage results in a change in a normal self protein to a non-self recognized protein, or it doesn't. Certain cancer types can be seen readily by the immune system, others can't. > In short I want to know the possibilities of that, can cancer or > maligencies be reversed by any mean instead of killing cancer cells by > medical aid? I have some clues(CAMs based) that fluorine, sulphur and > silicon as cal.fluoride, cal.sulphate, pot.sulphate and silicic acid > may have some relations to it. > I haven't heard about anything like that. It sounds like bunk to me
From: kumar on 15 Dec 2005 21:48 Mike McWilliams wrote: > kumar wrote: > > > I want to know that:- > > > > > > 1. Can cancer cells be mediated/encouraged to reverse/supress their DNA > > > > damages? If yes, how? > > If DNA damage has been passed down to a few generations, and you have a > clump of a million cancer cells with the same sequence damaged, you will > probably not be able to reverse the damage. > > It may be possible one day with gene therapy, but I wouldn't bet on that. Are we sure that cancer's DNA damages can be passed down to next generations? How? What about possibility of repairing these DNA damages with in one's lifetime? > > 2. Can cancer cells be mediated/encouraged to produce tumor-specific > > antigens or mutations/cancer specific antigens? How? > > > > > > Not really, either the damage results in a change in a normal self > protein to a non-self recognized protein, or it doesn't. > Certain cancer types can be seen readily by the immune system, others can't. Can it mean that immune system don't do or can't do anything to kill/control most of cancer cells? > > In short I want to know the possibilities of that, can cancer or > > maligencies be reversed by any mean instead of killing cancer cells by > > medical aid? I have some clues(CAMs based) that fluorine, sulphur and > > silicon as cal.fluoride, cal.sulphate, pot.sulphate and silicic acid > > may have some relations to it. > > > I haven't heard about anything like that. It sounds like bunk to me Can cancer causing agents result into calcifications, fats deposits(alike fatty degeneration), foreign material depositions, cell membrane changes, truma to cells causing somewhat scarring type effects to cell membrane...causing somewhat suffocations and DNA damages?
From: Mike McWilliams on 16 Dec 2005 11:30 kumar wrote: > Mike McWilliams wrote: > >>kumar wrote: >> >> >>>I want to know that:- >>> >>> >>>1. Can cancer cells be mediated/encouraged to reverse/supress their DNA >>> >>>damages? If yes, how? >> >>If DNA damage has been passed down to a few generations, and you have a >>clump of a million cancer cells with the same sequence damaged, you will >>probably not be able to reverse the damage. >> >>It may be possible one day with gene therapy, but I wouldn't bet on that. > > > Are we sure that cancer's DNA damages can be passed down to next > generations? How? > What about possibility of repairing these DNA damages with in one's > lifetime? > Yes you can be sure that errors in one generation propogate to the next. This is essential to the progression of evolution. The chances of spontaneous repair depend. If the error is a base transversion, the chance of the correct base coming back in a future generation is low, but could happen in a statistically large population. The only way it would come back is through another error at the same base. This is a low probability. If the error is a deletion, the chances of repair are pretty well 0 if the error is a translocation, the chances are also pretty well 0 > >>>2. Can cancer cells be mediated/encouraged to produce tumor-specific >>>antigens or mutations/cancer specific antigens? How? >>> >>> >> >>Not really, either the damage results in a change in a normal self >>protein to a non-self recognized protein, or it doesn't. >>Certain cancer types can be seen readily by the immune system, others can't. > > > Can it mean that immune system don't do or can't do anything to > kill/control most of cancer cells? > Yes, thats the problem. Cancers are often entirely unrecognized. They only get recognized if they are producing signals which make them conspicuous. > >>>In short I want to know the possibilities of that, can cancer or >>>maligencies be reversed by any mean instead of killing cancer cells by >>>medical aid? I have some clues(CAMs based) that fluorine, sulphur and >>>silicon as cal.fluoride, cal.sulphate, pot.sulphate and silicic acid >>>may have some relations to it. >>> >> >>I haven't heard about anything like that. It sounds like bunk to me > > > Can cancer causing agents result into calcifications, fats > deposits(alike fatty degeneration), foreign material depositions, cell > membrane changes, truma to cells causing somewhat scarring type effects > to cell membrane...causing somewhat suffocations and DNA damages? > I'm not sure what you mean in that question
From: kumar on 16 Dec 2005 20:43 > I'm not sure what you mean in that question Mike, That is somewhat CAMs related. Few healing agents indicated for cancer do those jobs. So I just tried to check the link. Anyway just leave it. Pls clear this point. Can cencer's mutations or DNA dmages be reversed/corrected within the lifetime of a cancer patient?
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