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From: Frank Emens on 16 Jan 2008 23:12
I seem to have dropped in on the tail end of am exchange that
mentioned some problem with combining melatonin and the benadryl sleep
inducers.

Can someone fill me in on what is supposed to be the problem? the
combination works extremely well for me and has for some time.
From: Sue Morton on 17 Jan 2008 09:29
Hi Frank, I see you're using Forte Agent, you can retrieve older posts with
your newsreader to see the whole thread (assuming your provider hasn't
purged them yet.)

Below is what I posted, in case your server's posts have already been
purged:
--
Sue Morton

Frank Emens wrote:
> I seem to have dropped in on the tail end of am exchange that
> mentioned some problem with combining melatonin and the benadryl sleep
> inducers.
>
> Can someone fill me in on what is supposed to be the problem? the
> combination works extremely well for me and has for some time.


Thread: No rest from Benadryl or Melatonin
Sue Morton wrote:
> Be sure you are using your CPAP all night if trying sedation,
> especially if combining two or more that can interact and can
> suppress respiration. The CPAP is not a respirator and so not a
> guarantee, but think of it as insurance to help you keep breathing
> freely if necessary.
>
> Your pressure needs may also increase if using some types of sedation
> or combinations. Use a fully data capable CPAP if at al possible, to
> see if pressure needs to be increased while using these forms of
> sedation.
>
> This is one of several good sites for checking drug interactions:
> http://www.drugdigest.org/DD/Interaction/ChooseDrugs/1,4109,,00.html
>
> An excerpt from above site:
>
> "MELATONIN may interact with DIPHENHYDRAMINE, ORAL (in
> Diphenhydramine Oral)
>
> Both diphenhydramine, which is included in many non-prescription cold
> products and sleeping pills, and melatonin contain substances that may
> promote sedation. If they are used together, excessive drowsiness,
> slowed breathing, loss of muscle control, and even coma may result.
> In general, diphenhydramine and supplemental melatonin should not be
> taken at the same time. If they are used together and sedation
> increases to an unsafe level, either diphenhydramine or supplemental
> melatonin or both may need to be stopped. Discuss this potential
> interaction with your healthcare provider at your next appointment,
> or sooner if you think you are having problems.
>
> This interaction is well-documented and is considered moderate in
> severity."
>
> Be safe.


From: Frank Emens on 17 Jan 2008 09:38
On Thu, 17 Jan 2008 06:29:00 -0800, "Sue Morton"
<867-5309(a)domain.invalid> wrote:

>Hi Frank, I see you're using Forte Agent, you can retrieve older posts with
>your newsreader to see the whole thread (assuming your provider hasn't
>purged them yet.)
>
>Below is what I posted, in case your server's posts have already been
>purged:

Thanks. that is just what I needed to see. I'll double check with my
MD though he already knows I'm using the combination.
From: Sue Morton on 17 Jan 2008 09:52
Quite a few people are using this combination. I imagine how much risk that
is entailing depends on the individual, what might be fairly safe levels for
you might increase the risks too far for me, dunno. Speaking strictly for
myself I don't want to trade my insomnia and apnea for the risk of coma or
expiring in my sleep (not yet anyway). If I go long enough with this
insomnia (four years and counting now), then the risks may begin to look
more attractive to me. However, I *did* try for one week the standard dose
of diphenhydramine hcl (50mg) and 3mg melatonin with no effect. So for me
it's a bust.
--
Sue Morton

Frank Emens wrote:
> On Thu, 17 Jan 2008 06:29:00 -0800, "Sue Morton"
> <867-5309(a)domain.invalid> wrote:
>
>> Hi Frank, I see you're using Forte Agent, you can retrieve older
>> posts with your newsreader to see the whole thread (assuming your
>> provider hasn't purged them yet.)
>>
>> Below is what I posted, in case your server's posts have already been
>> purged:
>
> Thanks. that is just what I needed to see. I'll double check with my
> MD though he already knows I'm using the combination.


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