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From: trigonometry1972 on 3 Jul 2008 21:08
Also notice they don't set the "bar" very high
so more people in this population are in
need of additional vitamin then suggested
the paper.

Arch Iran 2008 Jul;11(4):377-81.

Effects of age and renal function on vitamin D
status in men.

Masoompour SM, Sadegholvaad A, Larijani B,
Ranjbar-Omrani G.

Endocrine and Metabolism Research Center,
Nemazee Hospital,
Shiraz University of Medical Sciences,
Shiraz, Iran.
hormone(a)sums.ac.ir.

BACKGROUND:
In general, no study has examined the relationship
between vitamin D status and key parameters of bone
mineral homeostasis in healthy men in Iran. The
effects of age and renal function on vitamin D status
were determined in a cross-sectional study on a
healthy population of Iranian men.

METHODS:
From January through February 2001, 520 men,
aged 20 - 74 years were selected through
a cluster randomized sampling from Shiraz.
Serum 25-hydroxyvitamin D, intact
parathyroid hormone, calcium, phosphorus,
alkaline phosphatase, creatinine, and albumin
were measured. Pearson and partial correlation
coefficients were used to determine the association
between variables.

RESULTS:
Five hundred twenty men with a mean+/-SD age of
45+/-15 years and a mean+/-SD 25-hydroxyvitamin D
level of 35+/-17 nmol/L were enrolled into the
study. Over 33.9% of men in Shiraz had a
low level of 25-hydroxyvitamin D (</=25 nmol/L).
Serum 25-hydroxyvitamin D did not decline with age
in men. Serum parathyroid hormone increased significantly
by age in men, but it did not correlate with the
decline in creatinine clearance. Men had a decline
in serum phosphorus (r=0.23, P<0.0001) and calcium
(r=0.14,P=0.001) concentrations by age.
Creatinine clearance declined with age.

CONCLUSION:
In healthy men, the serum level of
25-hydroxyvitamin D did not decline with age.
Nonetheless, the prevalence of vitamin D
deficiency is high which warrants consideration
of dietary vitamin D supplement in men.


PMID: 18588368
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