Acute Backache and Moderate Sciatica
in [Nutrition]
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From: ironjustice on 3 Aug 2008 03:53 "Alpha-lipoic acid (thioctic acid) can also bind to, or chelate, metals like iron and copper." Summary# 46512 Alpha-Lipoic Acid and Acetyl-L-Carnitine in the Treatment of Sciatica "Thioctic Acid and acetyl-L-carnitine in the treatment of sciatic pain caused by a herniated disc: a randomized, double-blind, comparative study," Memeo A, Loiero M, et al, Clin Drug Investig, 2008; 28(8): 495-500. (Address: Ortopedia Pediatrica, Istituto Ortopedico Gaetano Pini, Milan, Italy). Summary: In a randomized, double-blind study involving 64 patients (mean age: 61 years) with acute backache and moderate sciatica, supplementation with 600 mg/d alpha-lipoic acid (thioctic acid) was found to be more effective than supplementation with 1180 mg/d acetyl-L-carnitine (ALC) in improving symptoms of sciatica over a 60 day intervention period. Greater improvements were found in patients who received thioctic acid, as compared to ALC, in terms of: neuropathy on electromyography (-0.19 vs. -0.09), score on the Neuropathy Impairment Score in the Lower Limbs (-2.52 vs. -1.48), score on the Neuropathy Symptoms and Change in the Lower Limbs (-2.16 vs. -1.42), and the Total Symptom Score (-1.90 vs. 1.18). Furthermore, a reduced need for analgesia was found among 71% of patients taking thioctic acid, and only 45.5% of patients taking ALC. The authors conclude that, "Thioctic acid 600 mg/day appears to be at least as effective as ALC in the treatment of sciatic pain caused by a herniated disc and may be associated with an improvement in symptom scores and reduced need for analgesia. However, because of the limited number of patients evaluated and the lack of a placebo control in this trial, further studies are warranted in order to provide more definitive results." Keywords: SCIATICA, CHRONIC PAIN, HERNIATED DISC - Alpha-Lipoic Acid, Thioctic Acid, Acetyl-L-Carnitine, Carnitine, Back, Buttocks, Legs Reference: Copyright © Vitasearch. All rights reserved. --------------------------- http://lpi.oregonstate.edu/ss03/lipoicacid.html The Role of Lipoic Acid in Inflammation and Atherosclerosis Alpha-lipoic acid can also bind to, or chelate, metals like iron and copper. Who loves ya. Tom Jesus Was A Vegetarian! http://tinyurl.com/2r2nkh Man Is A Herbivore! http://tinyurl.com/4rq595 DEAD PEOPLE WALKING http://tinyurl.com/zk9fk
From: Marcus Aurelius on 4 Aug 2008 18:25 An acute back ache can have many etiologies inclusive of osteoporosis,osteomyleitis, avascular necrosis of the bone, infectious arthritis, osteoarthritis, bone tumors (benign and cancerous) of the spine, spinal fractures, and other causes.The understanding of this factor should, concomittantly be expressed as a limited applicability of any medical procedure and/or treatment.
From: ironjustice on 4 Aug 2008 19:39 On Aug 4, 3:25 pm, Marcus Aurelius <alexander...(a)hotmail.com> wrote:Alpha-Lipoic Acid and Acetyl-L-Carnitine in the Treatment of Sciatica << Sciatica .. Sciatica is treated successfully with .. an iron chelator .. Don't like it .. ? Place an article which says .. "sciatica doesn't respond to the iron chelator alpha-lipoic acid" .. or something like that .. On Aug 4, 3:25 pm, Marcus Aurelius <alexander...(a)hotmail.com> wrote:limited applicability of any medical procedure and/or treatment << Sciatica treated with an iron chelator .. Take home message .. ? Sciatica treated with an iron chelator .. Who loves ya. Tom Jesus Was A Vegetarian! http://tinyurl.com/2r2nkh Man Is A Herbivore! http://tinyurl.com/4rq595 DEAD PEOPLE WALKING http://tinyurl.com/zk9fk > An acute back ache can have many etiologies inclusive of > osteoporosis,osteomyleitis, avascular necrosis of the bone, infectious > arthritis, osteoarthritis, bone tumors (benign and cancerous) of the > spine, spinal fractures, and other causes.The understanding of this > factor should, concomittantly be expressed as a limited applicability > of any medical procedure and/or treatment.
From: jay on 4 Aug 2008 21:34 > An acute back ache can have many etiologies inclusive of > osteoporosis,osteomyleitis, avascular necrosis of the bone, infectious > arthritis, osteoarthritis, bone tumors (benign and cancerous) of the > spine, spinal fractures, and other causes.The understanding of this > factor should, concomittantly be expressed as a limited applicability > of any medical procedure and/or treatment. Also, various lipophilic Persistent Organic Pollutants (ie dioxin) can cause sciatica. After being released into atmosphere, land, rivers and lakes, it biomagnifies as it moves up the food chain. Meat, fish, poultry, egg and dairy fats provide the most POPs. Fish raised in polluted waters or animals raised on contaminated feed can be especially high. In humans, POPs accumulate in body fat and nervous system. TCDD, a potent form of dioxin, can cause cellular ROS via multiple pathways including one that uses iron. Ingestion of low levels of POPs over many year can result in slowing developing symptoms that are very difficult to track down.
From: ironjustice on 4 Aug 2008 21:58
On Aug 4, 6:34 pm, jay <jaym1...(a)hotmail.com> wrote: snip << Iron chelator relieves .. sciatica .. You really are making it rather hard to understand what the article .. says .. Iron chelator relieves .. sciatica .. If you .. wish .. to .. wax .. onnnnn .. about HOW sciatica is .. caused .. or how it CAN be caused .. or HOW .. mannnnnyyyyyy .. ways it .. can be .. caused .. it really is .. unproductive .. If your doctor mentions sciatica TO .. you .. or if you EVER .. 'wondered' IF you DO .. have ..sciatica .. then .. ? Remember this .. Iron chelator relieves .. sciatica. THAT is **all** the article .. says. Which means .. again .. cup half full .. that an iron chelator MAY .. possibly .. work .. IN .. sciatica. Sciatica .. is .. painful .. ? Who loves ya. Tom Jesus Was A Vegetarian! http://tinyurl.com/2r2nkh Man Is A Herbivore! http://tinyurl.com/4rq595 DEAD PEOPLE WALKING http://tinyurl.com/zk9fk > > An acute back ache can have many etiologies inclusive of > > osteoporosis,osteomyleitis, avascular necrosis of the bone, infectious > > arthritis, osteoarthritis, bone tumors (benign and cancerous) of the > > spine, spinal fractures, and other causes.The understanding of this > > factor should, concomittantly be expressed as a limited applicability > > of any medical procedure and/or treatment. > > Also, various lipophilic Persistent Organic Pollutants (ie dioxin) can > cause sciatica. After being released into atmosphere, land, rivers and > lakes, it biomagnifies as it moves up the food chain. Meat, fish, > poultry, egg and dairy fats provide the most POPs. Fish raised in > polluted waters or animals raised on contaminated feed can be > especially high. In humans, POPs accumulate in body fat and nervous > system. TCDD, a potent form of dioxin, can cause cellular ROS via > multiple pathways including one that uses iron. Ingestion of low > levels of POPs over many year can result in slowing developing > symptoms that are very difficult to track down. |